WB (Western Blot)
(Western blot analysis analysis of different tissue and cell lysates using rabbit pAb against DJ1/Park7, RA22132, dilution 1:2,000 in green. [1] protein standard, [2] rat brain, [3] mouse brain, [4] rat embryonic neuron-glial cells, [5] NIH-3T3, [6] HEK293, and [7] HeLa cells.)
Rabbit DJ1/Park7 Polyclonal Antibody | anti-DJ1/Park7 antibody
DJ1/Park7 Polyclonal Rabbit Antibody
Gene Names
PARK7; DJ1; DJ-1; GATD2; HEL-S-67p
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, Immunocytochemistry
Synonyms
DJ1/Park7, Antibody; DJ1/Park7 Polyclonal Rabbit Antibody; anti-DJ1/Park7 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Form/Format
Liquid; Whole Serum
Sequence Length
189
Applicable Applications for anti-DJ1/Park7 antibody
IF (Immunofluorescence), WB (Western Blot), ICC (Immunocytochemistry)
Immunogen
Full length recombinant human DJ-1 expressed in and purified from E Coli
WB (Western Blot)
(Western blot analysis analysis of different tissue and cell lysates using rabbit pAb against DJ1/Park7, RA22132, dilution 1:2,000 in green. [1] protein standard, [2] rat brain, [3] mouse brain, [4] rat embryonic neuron-glial cells, [5] NIH-3T3, [6] HEK293, and [7] HeLa cells.)
WB (Western Blot)
(Western blot analysis analysis of different tissue and cell lysates using rabbit pAb against DJ1/Park7, RA22132, dilution 1:2,000 in green. [1] protein standard, [2] rat brain, [3] mouse brain, [4] rat embryonic neuron-glial cells, [5] NIH-3T3, [6] HEK293, and [7] HeLa cells.)
IF (Immunofluorescence)
(Immunofluorescent analysis analysis of SH-SY5Y cells stained with rabbit pAb against DJ1/Park7, RA22132, dilution 1:1,000 in red, and costained with mouse actin, dilution 1:200 in green. The blue is Hoechst staining of nuclear DNA.)
IF (Immunofluorescence)
(Immunofluorescent analysis analysis of SH-SY5Y cells stained with rabbit pAb against DJ1/Park7, RA22132, dilution 1:1,000 in red, and costained with mouse actin, dilution 1:200 in green. The blue is Hoechst staining of nuclear DNA.)
Related Product Information for anti-DJ1/Park7 antibody
DJ1, also known as PARK7, is a soluble protein which belongs to the ThiJ/Pfp1/DJ1 superfamily. DJ1 was originally cloned as an oncogene that cooperatively transforms cells together with H-ras (1). Mutations in the DJ1 gene are associated with rare forms of autosomal recessive early-onset Parkinson's disease (2). DJ-1 is a multifunctional protein that participates in transcriptional regulation, anti oxidative stress reaction, and chaperone, protease, and mitochondrial regulation. DJ1 may also function as an sensor for oxidative stress, and it protects neurons against oxidative stress and cell death (3-5). DJ-1 is expressed in almost all cells and tissues. DJ-1 is located in the cytoplasm, nucleus, and mitochondria in cells, and secreted DJ-1 has been observed in various cultured cells and tissues. Augmenting DJ1 activity might provide novel approaches to treating chronic neurodegenerative illnesses such as Parkinson's disease and acute damage such as stroke (6). The HGNC name for this protein is PARK7. The antibody was generated against full length recombinant human DJ1 protein expressed in and purified from E Coli. This antibody binds to the human, rat and mouse DJ1 proteins. The rodent protein is about 91% identical to the human protein.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
protein/nucleic acid deglycase DJ-1
NCBI Official Synonym Full Names
Parkinsonism associated deglycase
NCBI Official Symbol
PARK7
NCBI Official Synonym Symbols
DJ1; DJ-1; GATD2; HEL-S-67p
NCBI Protein Information
protein/nucleic acid deglycase DJ-1
UniProt Protein Name
Protein DJ-1
UniProt Gene Name
PARK7
UniProt Entry Name
PARK7_HUMAN
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Product Notes
The DJ1/Park7 park7 (Catalog #AAA76615) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DJ1/Park7 Polyclonal Rabbit Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DJ1/Park7 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ICC (Immunocytochemistry). Researchers should empirically determine the suitability of the DJ1/Park7 park7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DJ1/Park7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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