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product-image-AAA303891_IF11.jpg IF (Immunofluorescence) (Immunofluorescence analysis of methanol-fixed HeLa, using DNA polymerase gamma antibody at 1: 200 dilution.)

Rabbit anti-Human DNA Polymerase gamma Polyclonal Antibody | anti-POLG antibody

DNA Polymerase gamma antibody

Gene Names
POLG; PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Purified by antigen-affinity chromatography.
Synonyms
DNA Polymerase gamma, Antibody; DNA Polymerase gamma antibody; anti-POLG antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 1XPBS, 1%BSA, 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Concentration
0.67 mg/ml (varies by lot)
Sequence Length
1239
Applicable Applications for anti-POLG antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant protein
Immunogen Description
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 779 and 1191 (P54098) of DNA polymerase gamma
Target Name
DNA Polymerase gamma
Preparation and Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

IF (Immunofluorescence)

(Immunofluorescence analysis of methanol-fixed HeLa, using DNA polymerase gamma antibody at 1: 200 dilution.)

product-image-AAA303891_IF11.jpg IF (Immunofluorescence) (Immunofluorescence analysis of methanol-fixed HeLa, using DNA polymerase gamma antibody at 1: 200 dilution.)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded Skeletal Muscle, using DNA polymerase gamma antibody(10 ug/ml).)

product-image-AAA303891_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemical analysis of paraffin-embedded Skeletal Muscle, using DNA polymerase gamma antibody(10 ug/ml).)

SDS-PAGE

(Sample (30 ug of whole cell lysate) A: MCF-7 5% SDS PAGE Primary antibody diluted at 1: 1000)

product-image-AAA303891_SDS_PAGE15.jpg SDS-PAGE (Sample (30 ug of whole cell lysate) A: MCF-7 5% SDS PAGE Primary antibody diluted at 1: 1000)
Related Product Information for anti-POLG antibody
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Product Categories/Family for anti-POLG antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
140kd
NCBI Official Full Name
DNA polymerase subunit gamma-1
NCBI Official Synonym Full Names
polymerase (DNA directed), gamma
NCBI Official Symbol
POLG
NCBI Official Synonym Symbols
PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B
NCBI Protein Information
DNA polymerase subunit gamma-1
UniProt Protein Name
DNA polymerase subunit gamma-1
UniProt Gene Name
POLG
UniProt Synonym Gene Names
MDP1; POLG1; POLGA
UniProt Entry Name
DPOG1_HUMAN

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Product Notes

The POLG polg (Catalog #AAA303891) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DNA Polymerase gamma antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DNA Polymerase gamma can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the POLG polg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNA Polymerase gamma, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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