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IHC (Immunohistochemistry)
(Immunohistochemical staining of paraffin-embedded Skeletal Muscle using DNA polymerase gamma antibody)
Rabbit DNA polymerase gamma Polyclonal Antibody | anti-DNA antibody
DNA polymerase gamma antibody
Gene Names
POLG; PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
Purity
DNA polymerase gamma antibody was purified by antigen-affinity chromatography
Synonyms
DNA polymerase gamma, Antibody; DNA polymerase gamma antibody; Polyclonal DNA polymerase gamma; Anti-DNA polymerase gamma; PolG-alpha; FLJ27114; MIRAS; MTDPS4A; PEO; POLG1; SANDO; MTDPS4B; MDP1; mitochondrial DNA polymerase catalytic subunit; PolG catalytic subunit; POLG; POLGA; SCAE; DNA polymerase subunit gamma-1; anti-DNA antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
DNA polymerase gamma antibody was purified by antigen-affinity chromatography
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
0.67 mg/ml (varies by lot)
Sequence Length
1239
Applicable Applications for anti-DNA antibody
WB (Western Blot), IHC (Immunohistochemistry), ICC (Immunocytochemistry), IF (Immunofluorescence)
Biological Significance
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE).
Cross-Reactivity
Human
Immunogen
DNA polymerase gamma antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 779 and 1231 of DNA polymerase gamma
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
IHC (Immunohistochemistry)
(Immunohistochemical staining of paraffin-embedded Skeletal Muscle using DNA polymerase gamma antibody)
IHC (Immunohistochemistry)
(Immunohistochemical staining of paraffin-embedded Skeletal Muscle using DNA polymerase gamma antibody)
IF (Immunofluorescence)
(Immunofluorescence analysis of methanol-fixed HeLa, using DNA polymerase gamma antibody at 1:200 dilution.)
IF (Immunofluorescence)
(Immunofluorescence analysis of methanol-fixed HeLa, using DNA polymerase gamma antibody at 1:200 dilution.)
WB (Western Blot)
(Western blot analysis of 30 ug of whole cell lysate (A: MCF-7) using a 5 % SDS PAGE gel and DNA polymerase gamma antibody at a dilution of 1:1000)
WB (Western Blot)
(Western blot analysis of 30 ug of whole cell lysate (A: MCF-7) using a 5 % SDS PAGE gel and DNA polymerase gamma antibody at a dilution of 1:1000)
WB (Western Blot)
(Western blot analysis of A. 50 ug Rat testis lysate/extract using a 5 % SDS PAGE gel and DNA polymerase gamma antibody at a dilution of 1:1000)
WB (Western Blot)
(Western blot analysis of A. 50 ug Rat testis lysate/extract using a 5 % SDS PAGE gel and DNA polymerase gamma antibody at a dilution of 1:1000)
Related Product Information for anti-DNA antibody
Affinity purified Rabbit polyclonal DNA polymerase gamma antibody
Product Categories/Family for anti-DNA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
140 kDa
NCBI Official Full Name
DNA polymerase gamma
NCBI Official Synonym Full Names
polymerase (DNA directed), gamma
NCBI Official Symbol
POLG
NCBI Official Synonym Symbols
PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B
NCBI Protein Information
DNA polymerase subunit gamma-1
UniProt Protein Name
DNA polymerase subunit gamma-1
UniProt Gene Name
POLG
UniProt Synonym Gene Names
MDP1; POLG1; POLGA
UniProt Entry Name
DPOG1_HUMAN
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Product Notes
The DNA polg (Catalog #AAA107940) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DNA polymerase gamma can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ICC (Immunocytochemistry), IF (Immunofluorescence). Researchers should empirically determine the suitability of the DNA polg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNA polymerase gamma, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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