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product-image-AAA49939_AD13.jpg Application Data (Immunocytochemical staining of Jurkat cells with Rabbit anti Human DR3 (AAA49939))

Rabbit anti-Mouse DR3 Polyclonal Antibody | anti-DR3 antibody

RABBIT ANTI HUMAN DR3 (ED)

Gene Names
TNFRSF25; DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12
Reactivity
Mouse
Applications
Western Blot, Immunohistochemistry
Synonyms
DR3, Antibody; RABBIT ANTI HUMAN DR3 (ED); anti-DR3 antibody
Ordering
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 0.5mg/ml (varies by lot)
Sequence Length
181
Applicable Applications for anti-DR3 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Perservative Stabilisers
0.02% Sodium Azide
Buffer Solution
Phosphate buffered saline
Antiserum Preparation
Antisera to DR3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Application Data

(Immunocytochemical staining of Jurkat cells with Rabbit anti Human DR3 (AAA49939))

product-image-AAA49939_AD13.jpg Application Data (Immunocytochemical staining of Jurkat cells with Rabbit anti Human DR3 (AAA49939))

Application Data

(Western blot analysis of Jurkat whole cell lysate probed with Rabbit anti Human DR3 (AAA49939))

product-image-AAA49939_AD15.jpg Application Data (Western blot analysis of Jurkat whole cell lysate probed with Rabbit anti Human DR3 (AAA49939))
Related Product Information for anti-DR3 antibody
Rabbit anti Human DR3 recognizes death receptor 3. DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas/CD95 (Chinnaiyan, A. et al. 1996). The receptor for DR3 has very recently been identified and has been termed Apo-3L (Marsters, S. et al. 1998). DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, a functionally induces apoptosis and NF-KB activation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,111 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 25 isoform 12
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 25
NCBI Official Symbol
TNFRSF25
NCBI Official Synonym Symbols
DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12
NCBI Protein Information
tumor necrosis factor receptor superfamily member 25; apoptosis inducing receptor; apoptosis-inducing receptor AIR; apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; death domain receptor 3 soluble form; death receptor beta; lymphocyte-associated receptor of death; protein WSL-1; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 25
UniProt Gene Name
TNFRSF25
UniProt Synonym Gene Names
APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; LARD
UniProt Entry Name
TNR25_HUMAN

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Product Notes

The DR3 tnfrsf25 (Catalog #AAA49939) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI HUMAN DR3 (ED) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DR3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the DR3 tnfrsf25 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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