ICC (Immunocytochemistry)
(Immunocytochemistry of DR3 in Jurkat cells with DR3 antibody at 10 ug/mL.)
Rabbit anti-Human, Mouse DR3 Polyclonal Antibody | anti-DR3 antibody
DR3 Antibody
Gene Names
TNFRSF25; DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
DEAE purified
Synonyms
DR3, Antibody; DR3 Antibody; Wsl-1 Apo-3; anti-DR3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
DEAE purified
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
417
Applicable Applications for anti-DR3 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a peptide corresponding to amino acids in extracellular domain of human DR3 precusor.
Target Name
DR3
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of DR3 in Jurkat cells with DR3 antibody at 10 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of DR3 in Jurkat cells with DR3 antibody at 10 ug/mL.)
WB (Western Blot)
(Western blot analysis of DR3 in Jurkat total cell lysate with DR3 antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of DR3 in Jurkat total cell lysate with DR3 antibody at 1:1000 dilution.)
Related Product Information for anti-DR3 antibody
Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kB activation.
Product Categories/Family for anti-DR3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
29,111 Da
NCBI Official Full Name
DR3
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 25
NCBI Official Symbol
TNFRSF25
NCBI Official Synonym Symbols
DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12
NCBI Protein Information
tumor necrosis factor receptor superfamily member 25
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 25
UniProt Gene Name
TNFRSF25
UniProt Synonym Gene Names
APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; LARD
UniProt Entry Name
TNR25_HUMAN
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Product Notes
The DR3 tnfrsf25 (Catalog #AAA301721) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DR3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DR3 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the DR3 tnfrsf25 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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