IF (Immunofluorescence)
(Immunofluorescence of ESR1 in rat brain tissue with ESR1 antibody at 20 μg/mL.)
Rabbit ESR1 Polyclonal Antibody | anti-ESR1 antibody
ESR1 Antibody
Gene Names
ESR1; ER; ESR; Era; ESRA; ESTRR; NR3A1
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
ESR1 Antibody is affinity chromatography purified via peptide column.
Synonyms
ESR1, Antibody; ESR1 Antibody; ESR1; ER; ESR; Era; ESRA; ESTRR; NR3A1; Estrogen receptor; ER-alpha; estrogen receptor 1; anti-ESR1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
ESR1 antibody is human, mouse and rat reactive.
Purity/Purification
ESR1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
595
Applicable Applications for anti-ESR1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
ESR1 antibody was raised against an 18 amino acid peptide near the center of human ESR1.
Buffer
ESR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ESR1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IF (Immunofluorescence)
(Immunofluorescence of ESR1 in rat brain tissue with ESR1 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of ESR1 in rat brain tissue with ESR1 antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of ESR1 in rat brain tissue with ESR1 antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of ESR1 in rat brain tissue with ESR1 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of ESR1 in rat brain tissue lysate with ESR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of ESR1 in rat brain tissue lysate with ESR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-ESR1 antibody
ESR1 Antibody: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors (1). Estrogen receptors, including ESR1, also known as ER-alpha and ESR2 (ER-beta), contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ESR1 is a widely expressed nuclear protein and serves as a strong activator of estrogen responsive genes (1,2). Phosphorylation of serines 104 and 106, located in the N-terminal transcription activation function-1 domain (AF-1), plays a large role in regulating ER alpha activity (3).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 65 kDa
Observed: 62 kDa
Observed: 62 kDa
NCBI Official Full Name
estrogen receptor isoform 1
NCBI Official Synonym Full Names
estrogen receptor 1
NCBI Official Symbol
ESR1
NCBI Official Synonym Symbols
ER; ESR; Era; ESRA; ESTRR; NR3A1
NCBI Protein Information
estrogen receptor; ER-alpha; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; nuclear receptor subfamily 3 group A member 1
UniProt Protein Name
Estrogen receptor
UniProt Gene Name
ESR1
UniProt Synonym Gene Names
ESR; NR3A1; ER
UniProt Entry Name
ESR1_HUMAN
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Product Notes
The ESR1 esr1 (Catalog #AAA40763) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ESR1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ESR1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ESR1 esr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ESR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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