IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human breast cancer using AAA119333 at dilution 1:100)
Rabbit anti-Human GTP-binding nuclear protein Ran Polyclonal Antibody | anti-RAN antibody
Rabbit anti-human GTP-binding nuclear protein Ran polyclonal Antibody(RAN)
Gene Names
RAN; TC4; Gsp1; ARA24
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Antigen Affinity Purified
Synonyms
GTP-binding nuclear protein Ran, Antibody; Rabbit anti-human GTP-binding nuclear protein Ran polyclonal Antibody(RAN); Androgen receptor-associated protein 24; GTPase Ran; Ras-like protein TC4; Ras-related nuclear protein; RAN; ARA24; anti-RAN antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
128
Applicable Applications for anti-RAN antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human GTP-binding nuclear protein Ran protein (1-216aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1156 / sc-1155 / sc-20802
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human breast cancer using AAA119333 at dilution 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human breast cancer using AAA119333 at dilution 1:100)
WB (Western Blot)
(All lanes: GTP-binding nuclear protein Ran antibody at 2ug/mlLane 1:Hela whole cell lysateLane 2:jurkat whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 24kDaObserved band size: 24kDa)
WB (Western Blot)
(All lanes: GTP-binding nuclear protein Ran antibody at 2ug/mlLane 1:Hela whole cell lysateLane 2:jurkat whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 24kDaObserved band size: 24kDa)
Related Product Information for anti-RAN antibody
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,423 Da
NCBI Official Full Name
GTP-binding nuclear protein Ran isoform 2
NCBI Official Synonym Full Names
RAN, member RAS oncogene family
NCBI Official Symbol
RAN
NCBI Official Synonym Symbols
TC4; Gsp1; ARA24
NCBI Protein Information
GTP-binding nuclear protein Ran
UniProt Protein Name
GTP-binding nuclear protein Ran
UniProt Gene Name
RAN
UniProt Synonym Gene Names
ARA24
UniProt Entry Name
RAN_HUMAN
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Product Notes
The RAN ran (Catalog #AAA119333) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human GTP-binding nuclear protein Ran polyclonal Antibody(RAN) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GTP-binding nuclear protein Ran can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the RAN ran for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GTP-binding nuclear protein Ran, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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