IHC (Immunohiostchemistry)
(Anti-HLA DMB antibody, AAA44950, IHC(P)IHC(P): Human Mammary Cancer Tissue)
Rabbit anti-Human HLA DMB Polyclonal Antibody | anti-HLA-DMB antibody
Anti-HLA DMB antibody
Gene Names
HLA-DMB; RING7; D6S221E
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
HLA DMB, Antibody; Anti-HLA DMB antibody; HLA class II histocompatibility antigen, DM beta chain; major histocompatibility complex, class II, DM beta; class II antigen HLA-DM beta chain antibody; class II histocompatibility antigen antibody; Class II histocompatibility antigen M beta chain antibody; D6S221E antibody; DMB antibody; HLA class II histocompatibility antigen DM beta chain antibody; HLA-DM histocompatibility type, beta chain antibody; M beta chain antibody; Major histocompatibility complex class II DM beta antibody; MHC class II antigen DMB antibody; MHC class II antigen HLA DM beta chain antibody; MHC class II HLA DMB antibody; OTTHUMP00000029257 antibody; Really interesting new gene 7 protein antibody; RING 7 antibody; RING7 antibody; anti-HLA-DMB antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
263
Applicable Applications for anti-HLA-DMB antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human HLA DMB (81-100aa NQKDTLMQRLRNGLQNCATH).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-HLA DMB antibody, AAA44950, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-HLA DMB antibody, AAA44950, IHC(P)IHC(P): Human Mammary Cancer Tissue)
WB (Western Blot)
(Anti-HLA DMB antibody, AAA44950, Western blottingAll lanes: Anti HLA DMB (AAA44950) at 0.5ug/mlLane 1: JURKAT Whole Cell Lysate at 40ugLane 2: JURKAT Whole Cell Lysate at 40ugLane 3: RAJI Whole Cell Lysate at 40ugLane 4: HUT Whole Cell Lysate at 40ugPredicted bind size: 29KDObserved bind size: 29KD)
WB (Western Blot)
(Anti-HLA DMB antibody, AAA44950, Western blottingAll lanes: Anti HLA DMB (AAA44950) at 0.5ug/mlLane 1: JURKAT Whole Cell Lysate at 40ugLane 2: JURKAT Whole Cell Lysate at 40ugLane 3: RAJI Whole Cell Lysate at 40ugLane 4: HUT Whole Cell Lysate at 40ugPredicted bind size: 29KDObserved bind size: 29KD)
Related Product Information for anti-HLA-DMB antibody
Description: Rabbit IgG polyclonal antibody for HLA class II histocompatibility antigen, DM beta chain(HLA-DMB) detection. Tested with WB, IHC-P in Human.
Background: HLA-DMB(major histocompatibility complex, class II, DM beta), also known as D6S221E, RING7, HLA-DM histocompatibility type, beta chain, HLADMB or RING7, is a protein that in humans is encoded by the HLA-DMB gene. The HLA-DMB gene is mapped on 6p21.32. HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha(DMA) and a beta(DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP(class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa and its gene contains 6 exons. HLA-DMA and -DMB appear to encode subunits of a functional heterodimer that is critical in the pathway of class II antigen presentation.
Background: HLA-DMB(major histocompatibility complex, class II, DM beta), also known as D6S221E, RING7, HLA-DM histocompatibility type, beta chain, HLADMB or RING7, is a protein that in humans is encoded by the HLA-DMB gene. The HLA-DMB gene is mapped on 6p21.32. HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha(DMA) and a beta(DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP(class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa and its gene contains 6 exons. HLA-DMA and -DMB appear to encode subunits of a functional heterodimer that is critical in the pathway of class II antigen presentation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
28,943 Da
NCBI Official Full Name
HLA class II histocompatibility antigen, DM beta chain
NCBI Official Synonym Full Names
major histocompatibility complex, class II, DM beta
NCBI Official Symbol
HLA-DMB
NCBI Official Synonym Symbols
RING7; D6S221E
NCBI Protein Information
HLA class II histocompatibility antigen, DM beta chain; MHC class II HLA-DMB; MHC class II antigen DMB; really interesting new gene 7 protein; MHC class II antigen HLA-DM beta chain; class II histocompatibility antigen, M beta chain
UniProt Protein Name
HLA class II histocompatibility antigen, DM beta chain
UniProt Gene Name
HLA-DMB
UniProt Synonym Gene Names
DMB; RING7
UniProt Entry Name
DMB_HUMAN
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Product Notes
The HLA-DMB hla-dmb (Catalog #AAA44950) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-HLA DMB antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HLA DMB can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the HLA-DMB hla-dmb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HLA DMB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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