IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human breast cancer using AAA229864 at dilution 1:100)
Rabbit anti-Human, mouse KEAP1 Polyclonal Antibody | anti-KEAP1 antibody
KEAP1 Antibody
Gene Names
KEAP1; INrf2; KLHL19
Reactivity
Human, mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
KEAP1, Antibody; KEAP1 Antibody; Kelch-like ECH-associated protein 1; Cytosolic inhibitor of Nrf2; INrf2; Kelch-like protein 19; KEAP1; INRF2; KIAA0132; KLHL19; anti-KEAP1 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Liquid
Sequence Length
624
Applicable Applications for anti-KEAP1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Recombinant human Kelch-like ECH-associated protein 1 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-15244 / sc-15246 / sc-33894 / sc-33569
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human breast cancer using AAA229864 at dilution 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human breast cancer using AAA229864 at dilution 1:100)
WB (Western Blot)
(Western blotAll lanes: KEAP1 antibody at 2ug/mlLane 1:mouse kidney tissueLane 2:NIH3T3 cellsSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 70kDaObserved band size: 70kDa)
WB (Western Blot)
(Western blotAll lanes: KEAP1 antibody at 2ug/mlLane 1:mouse kidney tissueLane 2:NIH3T3 cellsSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 70kDaObserved band size: 70kDa)
Related Product Information for anti-KEAP1 antibody
Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,666 Da
NCBI Official Full Name
kelch-like ECH-associated protein 1
NCBI Official Synonym Full Names
kelch like ECH associated protein 1
NCBI Official Symbol
KEAP1
NCBI Official Synonym Symbols
INrf2; KLHL19
NCBI Protein Information
kelch-like ECH-associated protein 1
UniProt Protein Name
Kelch-like ECH-associated protein 1
UniProt Gene Name
KEAP1
UniProt Synonym Gene Names
INRF2; KIAA0132; KLHL19; INrf2
UniProt Entry Name
KEAP1_HUMAN
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Product Notes
The KEAP1 keap1 (Catalog #AAA229864) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KEAP1 Antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KEAP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the KEAP1 keap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KEAP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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