IHC (Immunohiostchemistry)
(Immunohistochemistry of Livin in human small intestine tissue with Livin antibody at 5 ug/mL.)
Rabbit anti-Human Livin Polyclonal Antibody | anti-Livin antibody
Livin Antibody
Gene Names
BIRC7; KIAP; LIVIN; MLIAP; RNF50; ML-IAP
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Livin, Antibody; Livin Antibody; KIAP; anti-Livin antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
A lower but much weaker band at 30 kDa was detected in Raji cell lysate, which may represent the short form of Livin.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
280
Applicable Applications for anti-Livin antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Livin antibody was raised with a synthetic peptide corresponding to amino acids 264 to 280 of. The short form and 281 to 298 of the long form of human Livin. This sequence is identical between a and b forms of the Livin proteins.
Target Name
Livin
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of Livin in human small intestine tissue with Livin antibody at 5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of Livin in human small intestine tissue with Livin antibody at 5 ug/mL.)
WB (Western Blot)
(Western blot analysis of Livin expression in human Raji cell lysate with Livin antibody at 0.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of Livin expression in human Raji cell lysate with Livin antibody at 0.5 ug/mL.)
Related Product Information for anti-Livin antibody
Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel member in the IAP protein family was recently identified and designated Livin and KIAP for kidney IAP. Livin/XIAP contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin-alpha and Livin-beta. Transfection of Livin in cells resulted in protection from apoptosis induced by FADD, BAX, RIP, RIP3 and DR6. Livin has direct interaction with several caspases including caspase-3, -7, and -9. Livin inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP. The two isoforms of Livin appear to have different functions and tissue distributions.
Product Categories/Family for anti-Livin antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,866 Da
NCBI Official Full Name
baculoviral IAP repeat-containing protein 7 isoform beta
NCBI Official Synonym Full Names
baculoviral IAP repeat containing 7
NCBI Official Symbol
BIRC7
NCBI Official Synonym Symbols
KIAP; LIVIN; MLIAP; RNF50; ML-IAP
NCBI Protein Information
baculoviral IAP repeat-containing protein 7
UniProt Protein Name
Baculoviral IAP repeat-containing protein 7
UniProt Gene Name
BIRC7
UniProt Synonym Gene Names
KIAP; LIVIN; MLIAP; RNF50; KIAP; ML-IAP; Truncated livin; p30-Livin; tLivin
UniProt Entry Name
BIRC7_HUMAN
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Product Notes
The Livin birc7 (Catalog #AAA303020) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Livin Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Livin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Livin birc7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Livin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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