IHC (Immunohiostchemistry)
(NKX6-1 Antibody-Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human NKX6-1 Polyclonal Antibody | anti-NKX6-1 antibody
NKX6-1 Rabbit anti-Human Polyclonal Antibody
Gene Names
NKX6-1; NKX6A; NKX6.1
Reactivity
Human
Applications
Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
NKX6-1, Antibody; NKX6-1 Rabbit anti-Human Polyclonal Antibody; PathPlus NKX6-1 Antibody; NKX6-1; NKX6A; NK homeobox; family 6; A; NK6 homeobox 1; Homeobox protein Nkx-6.1; NKX6.1; anti-NKX6-1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.1% Sodium Azide
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-NKX6-1 antibody
IHC (Immunohistochemistry)
Target
Human NKX6-1
Immunogen
LP-11011, synthetic peptide
Conjugation
Unconjugated
Preparation and Storage
Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze-thaw cycles.
IHC (Immunohiostchemistry)
(NKX6-1 Antibody-Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(NKX6-1 Antibody-Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(NKX6-1 Antibody-Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(NKX6-1 Antibody-Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-NKX6-1 antibody
NKX6-1 antibody is an unconjugated rabbit polyclonal antibody to NKX6-1 from human. Validated for IHC.
NKX6-1 (NK6 homeobox 1) is a neuronal progenitor transcription factor that is induced by SHH signals. It binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. It functions in transcriptional regulation in islet beta cells, and binds to the insulin promoter and is involved in regulation of insulin. It restricts the generation of motor neurons to the appropriate region of the neural tube. It is considered a tumor suppressor via its ability to suppress the epithelial-to-mesenchymal transition, and loss of expression is correlated with metastasis in cervical cancer. In immunohistochemistry of normal tissue, NKX6-1 has nuclear positivity in islets of Langerhans in the pancreas, and is also found in the brain, thyroid, stomach, breast and testis.
NKX6-1 (NK6 homeobox 1) is a neuronal progenitor transcription factor that is induced by SHH signals. It binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. It functions in transcriptional regulation in islet beta cells, and binds to the insulin promoter and is involved in regulation of insulin. It restricts the generation of motor neurons to the appropriate region of the neural tube. It is considered a tumor suppressor via its ability to suppress the epithelial-to-mesenchymal transition, and loss of expression is correlated with metastasis in cervical cancer. In immunohistochemistry of normal tissue, NKX6-1 has nuclear positivity in islets of Langerhans in the pancreas, and is also found in the brain, thyroid, stomach, breast and testis.
References
The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; Oncogene. 2016 Apr 28;35(17):2266-78, PMID: 26257059;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,849 Da
NCBI Official Full Name
homeobox protein Nkx-6.1
NCBI Official Synonym Full Names
NK6 homeobox 1
NCBI Official Symbol
NKX6-1
NCBI Official Synonym Symbols
NKX6A; NKX6.1
NCBI Protein Information
homeobox protein Nkx-6.1
UniProt Protein Name
Homeobox protein Nkx-6.1
UniProt Gene Name
NKX6-1
UniProt Synonym Gene Names
NKX6A
Similar Products
Product Notes
The NKX6-1 nkx6-1 (Catalog #AAA163024) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NKX6-1 Rabbit anti-Human Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NKX6-1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the NKX6-1 nkx6-1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NKX6-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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