WB (Western Blot)
(Western Blot analysis of extracts from MCF cells untreated or treated with Anisomycin using p53 (Phospho-Ser46) antibody)
Rabbit p53 Polyclonal Antibody | anti-p53 antibody
p53 antibody
Gene Names
TP53; P53; BCC7; LFS1; TRP53
Applications
Western Blot, Immunofluorescence
Purity
Purified by immunoaffinity chromatography.
Synonyms
p53, Antibody; p53 antibody; Rabbit polyclonal p53 antibody; Polyclonal p53 antibody; Anti-p53 antibody; p53 Oncoprotein antibody; Phospho Ser46 antibody; p-53; p 53; p 53 antibody; p-53 antibody; p53; fb40d06 antibody; LFS1 antibody; Li-Fraumeni syndrome antibody; p53 tumor suppressor antibody; p53 tumor suppressor phosphoprotein antibody; phosphoprotein p53 antibody; transformation related protein 53 antibody; anti-p53 antibody
Host
Rabbit
Clonality
Polyclonal
Purity/Purification
Purified by immunoaffinity chromatography.
Form/Format
Liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl,0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
393
Applicable Applications for anti-p53 antibody
WB (Western Blot), IF (Immunofluorescence)
Immunogen
p53 antibody was raised in Rabbit using the peptide sequence around phosphorylation site of serine 46 (M-L-S(p)-P-D) derived from Human p53 as the immunogen.
Cross-Reactivity
Human, Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
WB (Western Blot)
(Western Blot analysis of extracts from MCF cells untreated or treated with Anisomycin using p53 (Phospho-Ser46) antibody)
WB (Western Blot)
(Western Blot analysis of extracts from MCF cells untreated or treated with Anisomycin using p53 (Phospho-Ser46) antibody)
IF (Immunofluorescence)
(Immunofluorescence staining of methanol-fixed Hela cells using p53 (Phospho-Ser46) antibody)
IF (Immunofluorescence)
(Immunofluorescence staining of methanol-fixed Hela cells using p53 (Phospho-Ser46) antibody)
Related Product Information for anti-p53 antibody
TP53 is found in increased amounts in a wide variety of transformed cells. TP53 is frequently mutated or inactivated in about 60% of cancers. TP53 defects are found in Barrett metaplasia a condition in which the normally stratified squamous epithelium of the lower esophagus is replaced by a metaplastic columnar epithelium. The condition develops as a complication in approximately 10% of patients with chronic gastroesophageal reflux disease and predisposes to the development of esophageal adenocarcinoma.
Product Categories/Family for anti-p53 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
24,401 Da
NCBI Official Full Name
P53
NCBI Official Synonym Full Names
tumor protein p53
NCBI Official Symbol
TP53
NCBI Official Synonym Symbols
P53; BCC7; LFS1; TRP53
NCBI Protein Information
cellular tumor antigen p53
UniProt Protein Name
Cellular tumor antigen p53
UniProt Gene Name
TP53
UniProt Synonym Gene Names
P53
Similar Products
Product Notes
The p53 tp53 (Catalog #AAA224795) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's p53 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence). Researchers should empirically determine the suitability of the p53 tp53 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p53, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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