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product-image-AAA179194_IP13.jpg IP (Immunoprecipitation) (Immunoprecipitation analysis of 900ug extracts of PC-3 cells usingug Pan Cadherin Polyclonal Antibody.Western blot was performed from the immunoprecipitate using Pan Cadherin Polyclonal Antibody at a dilution of 1:3000.)

Rabbit Pan Cadherin Polyclonal Antibody | anti-CDH1 antibody

Pan Cadherin Polyclonal Antibody

Gene Names
CDH1; UVO; CDHE; ECAD; LCAM; Arc-1; CD324
Reactivity
Human, Mouse, Rat
Applications
Immunoprecipitation, Western Blot
Purity
Affinity purification
Synonyms
Pan Cadherin, Antibody; Pan Cadherin Polyclonal Antibody; anti-CDH1 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-CDH1 antibody
IP (Immunoprecipitation), WB (Western Blot)
Immunogen
A synthetic peptide of human pan-cadherin
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.

IP (Immunoprecipitation)

(Immunoprecipitation analysis of 900ug extracts of PC-3 cells usingug Pan Cadherin Polyclonal Antibody.Western blot was performed from the immunoprecipitate using Pan Cadherin Polyclonal Antibody at a dilution of 1:3000.)

product-image-AAA179194_IP13.jpg IP (Immunoprecipitation) (Immunoprecipitation analysis of 900ug extracts of PC-3 cells usingug Pan Cadherin Polyclonal Antibody.Western blot was performed from the immunoprecipitate using Pan Cadherin Polyclonal Antibody at a dilution of 1:3000.)

WB (Western Blot)

(Western blot analysis of extracts of various cell lines using Pan Cadherin Polyclonal Antibody at 1:3000 dilution.)

product-image-AAA179194_WB15.jpg WB (Western Blot) (Western blot analysis of extracts of various cell lines using Pan Cadherin Polyclonal Antibody at 1:3000 dilution.)
Related Product Information for anti-CDH1 antibody
Cadherin is one of a class of integral-membrane glycoproteins that are involved in cell to cell attachment for preserving the integrity of all solid tissues. Cadherins have three major regions: the Ca2+ -dependent extracellular region that mediates adhesion (cadherin to cadherin) for cell to cell binding; the transmembrane region; and the cytoplasmic region that extends into the cell and interacts with catenins, which in turn are linked to the actin of the cytoskeleton. Cadherins are differentially expressed during development and in adult organs. Since many cell types express multiple cadherin subclasses simultaneously (the combination differs with cell type), it can be inferred that the adhesion properities of individual cells are thus governed by varying the combinations of cadherins. Altered expression of cadherins are involved in invasion and metastasis of tumour cells. The classical cadherins (e.g. E-, N-, and P-cadherins) are the most common family members. E-cadherin (also known as uvomorulin) is concentrated in the belt desmosome in epithelial cells; N-cadherin is found in nerve, muscle, and lens cells and helps maintain the integrity of neuronal aggregates; P-cadherin is expressed in placental and epidermal cells.
Product Categories/Family for anti-CDH1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
999
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
97,456 Da
NCBI Official Full Name
cadherin-1 preproprotein
NCBI Official Synonym Full Names
cadherin 1, type 1, E-cadherin (epithelial)
NCBI Official Symbol
CDH1
NCBI Official Synonym Symbols
UVO; CDHE; ECAD; LCAM; Arc-1; CD324
NCBI Protein Information
cadherin-1; CAM 120/80; E-Cadherin; uvomorulin; cell-CAM 120/80; epithelial cadherin; cadherin 1, E-cadherin (epithelial); calcium-dependent adhesion protein, epithelial
UniProt Protein Name
Cadherin-1
UniProt Gene Name
CDH1
UniProt Synonym Gene Names
CDHE; UVO; E-cadherin
UniProt Entry Name
CADH1_HUMAN

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Product Notes

The CDH1 cdh1 (Catalog #AAA179194) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Pan Cadherin Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Pan Cadherin can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the CDH1 cdh1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pan Cadherin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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