Rabbit anti-Mouse, Rat TIM-1 Polyclonal Antibody | anti-TIM-1 antibody

RABBIT ANTI TIM-1

Cat. Num. AAA49934

• Gene Names: HAVCR1; TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1
• Reactivity: Mouse, Rat
• Applications: Western Blot
• Synonyms: TIM-1, Antibody; RABBIT ANTI TIM-1; anti-TIM-1 antibody

• Host: Rabbit
• Reactivity: Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This item detects T cell immunoglobulin mucin-1 (TIM-1), which was first identified as the receptor used by hepatitis A for viral entry (it is also known as the hepatitis A virus cellular receptor- HAVCR). TIM-1 is a key cell surface protein that binds TIM-4, leading to T cell proliferation and T helper type 2 (Th2) cytokine production. TIM-1 has also been shown to bind and activate macrophages. ; ; Two splice variants for human TIM-1 exist; TIM-1a is predominantly expressed in the liver, whilst TIM-1b is expressed in the kidney. Expression of TIM-1 in the kidney is thought to be upregulated in damaged tissue, and is thought to assist healing. ; ; TIM-1 polymorphisms are associated with asthma.
• Form/Format: Purified; Purified IgG - liquid
• Concentration: IgG concentration 1.0mg/ml (varies by lot)
• Sequence Length: 364

• Applicable Applications for anti-TIM-1 antibody: WB (Western Blot)
• Perservative Stabilisers: 0.02% Sodium Azide
• Immunogen: 16 amino acid peptide sequence near the centre of human TIM-1.; Buffer Solution
• Antiserum Preparation: Antisera to human TIM-1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
• Target Species: Human
• Preparation and Storage: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.; Shelf Life: 18 months from date of despatch.

Application Data

(Western blot analysis of human uterine lysate probed with Rabbit anti Human TIM-1 (AAA49934) at 1(A) and 2(B) ug/ml)

Related Product Information for anti-TIM-1 antibody

MBS221475 detects T cell immunoglobulin mucin-1 (TIM-1), which was first identified as the receptor used by hepatitis A for viral entry (it is also known as the hepatitis A virus cellular receptor- HAVCR). TIM-1 is a key cell surface protein that binds TIM-4, leading to T cell proliferation and T helper type 2 (Th2) cytokine production. TIM-1 has also been shown to bind and activate macrophages. Two splice variants for human TIM-1 exist; TIM-1a is predominantly expressed in the liver, whilst TIM-1b is expressed in the kidney. Expression of TIM-1 in the kidney is thought to be upregulated in damaged tissue, and is thought to assist healing. TIM-1 polymorphisms are associated with asthma.

NCBI and Uniprot Product Information

• NCBI GI #: 153085429
• NCBI GeneID: 26762
• NCBI Accession #: NP_001092884.1
• NCBI GenBank Nucleotide #: NM_001099414.1
• UniProt Accession #: Q96D42; O43656
• Molecular Weight: 38,720 Da
• NCBI Official Full Name: hepatitis A virus cellular receptor 1
• NCBI Official Synonym Full Names: hepatitis A virus cellular receptor 1
• NCBI Official Symbol: HAVCR1
• NCBI Official Synonym Symbols: TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1
• NCBI Protein Information: hepatitis A virus cellular receptor 1; T cell immunoglobin domain and mucin domain protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; kidney injury molecule 1
• UniProt Protein Name: Hepatitis A virus cellular receptor 1
• UniProt Gene Name: HAVCR1
• UniProt Synonym Gene Names: KIM1; TIM1; TIMD1; HAVcr-1; KIM-1; TIMD-1; TIM; TIM-1
• UniProt Entry Name: HAVR1_HUMAN