Rabbit anti-Human TNFSF18 Polyclonal Antibody | anti-TNFSF18 antibody
TNFSF18 Polyclonal Antibody
Gene Names
TNFSF18; TL6; AITRL; GITRL; TNLG2A; hGITRL
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
TNFSF18, Antibody; TNFSF18 Polyclonal Antibody; Activation-inducible TNF-related ligand; AITRL; Glucocorticoid-induced TNF-related ligand; hGITRL; TNFSF18; GITRL; TL6; UNQ149/PRO175; anti-TNFSF18 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total TNFSF18 polyclonal antibody.
Purity/Purification
Antigen Affinity Purified
Form/Format
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
199
Applicable Applications for anti-TNFSF18 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein (72-199aa)
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
Related Product Information for anti-TNFSF18 antibody
Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells.Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation.
Product Categories/Family for anti-TNFSF18 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,724 Da
NCBI Official Full Name
tumor necrosis factor ligand superfamily member 18
NCBI Official Synonym Full Names
tumor necrosis factor superfamily member 18
NCBI Official Symbol
TNFSF18
NCBI Official Synonym Symbols
TL6; AITRL; GITRL; TNLG2A; hGITRL
NCBI Protein Information
tumor necrosis factor ligand superfamily member 18
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 18
UniProt Gene Name
TNFSF18
UniProt Synonym Gene Names
AITRL; GITRL; TL6; AITRL; hGITRL
UniProt Entry Name
TNF18_HUMAN
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Product Notes
The TNFSF18 tnfsf18 (Catalog #AAA309065) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TNFSF18 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TNFSF18 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TNFSF18 tnfsf18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNFSF18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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