Standard Curve (Sample)
Mouse GITRL ELISA Kit | TNFSF18 elisa kit
Mouse GITRL ELISA Kit
Gene Names
Tnfsf18; Gitrl; Tnlg2a
Reactivity
Mouse
Applications
ELISA
Synonyms
GITRL; N/A; Mouse GITRL ELISA Kit; AITRL; TL6; Tumor necrosis factor ligand superfamily member 18; Activation-inducible TNF-related ligand; Glucocorticoid-induced TNF-related ligand; hGITRL; TNFSF18 elisa kit
Reactivity
Mouse
Specificity
The Mouse GITRL ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse GITRL proteins within the range of 31.2 pg/ml - 2000 pg/ml.
Sequence Length
173
Samples
Cell Culture Supernatants, Serum, Plasma.
Sensitivity
10 pg/ml.
Applicable Applications for TNFSF18 elisa kit
ELISA (Sandwich ELISA)
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Standard Curve (Sample)
Standard Curve (Sample)
Related Product Information for TNFSF18 elisa kit
Principle of the Assay||The Mouse GITRL ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse GITRL in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Mouse GITRL coated on a 96-well plate. Standards and samples are pipetted into the wells and GITRL present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Mouse GITRL antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of GITRL bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background/Introduction: Tumor necrosis factor ligand superfamily member 18, also known as AITRL or GITRL, is a protein that in humans is encoded by the TNFSF18 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor(TNF) ligand family. It is mapped to 1q25.1. TNFSF18 is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. TNFSF18-dependent modulation of tryptophan catabolism may represent an important mechanism of action of glucocorticoids, both physiologically and therapeutically.
Background/Introduction: Tumor necrosis factor ligand superfamily member 18, also known as AITRL or GITRL, is a protein that in humans is encoded by the TNFSF18 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor(TNF) ligand family. It is mapped to 1q25.1. TNFSF18 is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. TNFSF18-dependent modulation of tryptophan catabolism may represent an important mechanism of action of glucocorticoids, both physiologically and therapeutically.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
19,732 Da
NCBI Official Full Name
Tumor necrosis factor ligand superfamily member 18
NCBI Official Synonym Full Names
tumor necrosis factor (ligand) superfamily, member 18
NCBI Official Symbol
Tnfsf18
NCBI Official Synonym Symbols
Gitrl; Tnlg2a
NCBI Protein Information
tumor necrosis factor ligand superfamily member 18
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 18
UniProt Gene Name
Tnfsf18
UniProt Synonym Gene Names
Gitrl; GITRL
UniProt Entry Name
TNF18_MOUSE
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Product Notes
The Mouse TNFSF18 tnfsf18 (Catalog #AAA261774) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA261774 ELISA Kit recognizes Mouse TNFSF18. AAA Biotech's GITRL can be used in a range of immunoassay formats including, but not limited to, ELISA (Sandwich ELISA). Researchers should empirically determine the suitability of the TNFSF18 tnfsf18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GITRL, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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