Standard Curve (Sample)
Human GITRL ELISA Kit | TNFSF18 elisa kit
Human GITRL ELISA Kit
Gene Names
TNFSF18; TL6; AITRL; GITRL; TNLG2A; hGITRL
Reactivity
Human
Synonyms
GITRL; N/A; Human GITRL ELISA Kit; AITRL; TL6; Tumor necrosis factor ligand superfamily member 18; Activation-inducible TNF-related ligand; Glucocorticoid-induced TNF-related ligand; hGITRL; TNFSF18 elisa kit
Reactivity
Human
Specificity
The Human GITRL ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human GITRL proteins within the range of 125 pg/ml - 8000 pg/ml.
Sequence Length
199
Samples
Cell Culture Supernates, Serum, Plasma
Sensitivity
<4 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Standard Curve (Sample)
Standard Curve (Sample)
Related Product Information for TNFSF18 elisa kit
Principle of the Assay: The Human GITRL ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human GITRL in Cell Culture Supernates, Serum, Plasma. This assay employs an antibody specific for Human GITRL coated on a 96-well plate. Standards and samples are pipetted into the wells and GITRL present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human GITRL antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of GITRL bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background: Tumor necrosis factor ligand superfamily member 18, also known as AITRL or GITRL, is a protein that in humans is encoded by the TNFSF18 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor(TNF) ligand family. It is mapped to 1q25.1. TNFSF18 is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. TNFSF18-dependent modulation of tryptophan catabolism may represent an important mechanism of action of glucocorticoids, both physiologically and therapeutically.
Background: Tumor necrosis factor ligand superfamily member 18, also known as AITRL or GITRL, is a protein that in humans is encoded by the TNFSF18 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor(TNF) ligand family. It is mapped to 1q25.1. TNFSF18 is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. TNFSF18-dependent modulation of tryptophan catabolism may represent an important mechanism of action of glucocorticoids, both physiologically and therapeutically.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,724 Da
NCBI Official Full Name
tumor necrosis factor ligand superfamily member 18
NCBI Official Synonym Full Names
tumor necrosis factor superfamily member 18
NCBI Official Symbol
TNFSF18
NCBI Official Synonym Symbols
TL6; AITRL; GITRL; TNLG2A; hGITRL
NCBI Protein Information
tumor necrosis factor ligand superfamily member 18
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 18
UniProt Gene Name
TNFSF18
UniProt Synonym Gene Names
AITRL; GITRL; TL6; AITRL; hGITRL
UniProt Entry Name
TNF18_HUMAN
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Product Notes
The Human TNFSF18 tnfsf18 (Catalog #AAA263094) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA263094 ELISA Kit recognizes Human TNFSF18. It is sometimes possible for the material contained within the vial of "GITRL, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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