Rabbit TOLLIP Polyclonal Antibody | anti-TOLLIP antibody

TOLLIP Antibody

Cat. Num. AAA39492

• Gene Names: TOLLIP; IL-1RAcPIP
• Reactivity: Human, Mouse, Rat
• Applications: Immunocytochemistry, Western Blot, ELISA
• Purity: TOLLIP Antibody is affinity chromatography purified via peptide column.
• Synonyms: TOLLIP, Antibody; TOLLIP Antibody; TOLLIP; IL-1RAcPIP; Toll-interacting protein; toll interacting protein; anti-TOLLIP antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: TOLLIP Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 274

• Applicable Applications for anti-TOLLIP antibody: ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: TOLLIP antibody was raised against a 16 amino acid synthetic peptide from near the center of human TOLLIP.
• Buffer: TOLLIP Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: TOLLIP antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

ICC (Immunocytochemistry)

(Immunocytochemistry of TOLLIP in THP-1 cells with TOLLIP antibody at 2 μg/mL.)

WB (Western Blot)

(Western blot analysis of TOLLIP in rat brain cell lysate with TOLLIP antibody at (A) 0.5, (B) 1 and (C) 2μg/mL.)

Related Product Information for anti-TOLLIP antibody

TOLLIP Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.

NCBI and Uniprot Product Information

• NCBI GI #: 17390641
• NCBI GeneID: 54472
• UniProt Accession #: Q9H0E2; Q9H9E6; Q9UJ69; B3KXC6
• Molecular Weight: 22,812 Da
• NCBI Official Full Name: Toll interacting protein
• NCBI Official Synonym Full Names: toll interacting protein
• NCBI Official Symbol: TOLLIP
• NCBI Official Synonym Symbols: IL-1RAcPIP
• NCBI Protein Information: toll-interacting protein; adapter protein
• UniProt Protein Name: Toll-interacting protein
• UniProt Gene Name: TOLLIP
• UniProt Entry Name: TOLIP_HUMAN