IHC (Immunohiostchemistry)
(Anti-Tollip antibody, AAA45484, IHC(P)IHC(P): Human Prostatic Cancer Tissue)
Rabbit anti-Human Tollip Polyclonal Antibody | anti-TOLLIP antibody
Anti-Tollip antibody
Gene Names
TOLLIP; IL-1RAcPIP
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Tollip, Antibody; Anti-Tollip antibody; Toll-interacting protein; toll interacting protein; Adapter protein antibody; FLJ33531 antibody; IL 1RAcPIP antibody; IL1RAcPIP antibody; TOLIP antibody; TOLIP_HUMAN antibody; Toll interacting protein antibody; Toll-interacting protein antibody; tollip antibody; anti-TOLLIP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
274
Applicable Applications for anti-TOLLIP antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Tollip (224-243aa NAQPRCSEEDLKAIQDMFPN).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-Tollip antibody, AAA45484, IHC(P)IHC(P): Human Prostatic Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-Tollip antibody, AAA45484, IHC(P)IHC(P): Human Prostatic Cancer Tissue)
WB (Western Blot)
(Anti-Tollip antibody, AAA45484, Western blottingLane 1: PANC Cell LysateLane 2: HELA Cell LysateLane 3: U87 Cell Lysate)
WB (Western Blot)
(Anti-Tollip antibody, AAA45484, Western blottingLane 1: PANC Cell LysateLane 2: HELA Cell LysateLane 3: U87 Cell Lysate)
Related Product Information for anti-TOLLIP antibody
Description: Rabbit IgG polyclonal antibody for Toll-interacting protein(TOLLIP) detection. Tested with WB, IHC-P in Human.
Background: TOLLIP(TOLL-Interacting Protein), is an inhibitory adaptor protein that in humans is encoded by the TOLLIP gene. Lo et al.(2009) stated that the TOLLIP gene maps to chromosome 11. The mouse gene maps to chromosome 7. By Western blot analysis of embryonic kidney cells, Burns et al.(2000) confirmed the binding of TOLLIP to IL1RAP, to a complex of IL1RAP-IL1R1, and to IL18R. Burns et al.(2000) proposed that IL1B stimulation induces aggregation of IL1Rs, recruitment of MYD88 followed by TOLLIP-IRAK complexes, and the phosphorylation of IRAK by MYD88. This leads to the dissociation of TOLLIP from IRAK, which can then transmit the IL1-induced signals.
Background: TOLLIP(TOLL-Interacting Protein), is an inhibitory adaptor protein that in humans is encoded by the TOLLIP gene. Lo et al.(2009) stated that the TOLLIP gene maps to chromosome 11. The mouse gene maps to chromosome 7. By Western blot analysis of embryonic kidney cells, Burns et al.(2000) confirmed the binding of TOLLIP to IL1RAP, to a complex of IL1RAP-IL1R1, and to IL18R. Burns et al.(2000) proposed that IL1B stimulation induces aggregation of IL1Rs, recruitment of MYD88 followed by TOLLIP-IRAK complexes, and the phosphorylation of IRAK by MYD88. This leads to the dissociation of TOLLIP from IRAK, which can then transmit the IL1-induced signals.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
22,812 Da
NCBI Official Full Name
Toll-interacting protein
NCBI Official Synonym Full Names
toll interacting protein
NCBI Official Symbol
TOLLIP
NCBI Official Synonym Symbols
IL-1RAcPIP
NCBI Protein Information
toll-interacting protein; adapter protein
UniProt Protein Name
Toll-interacting protein
UniProt Gene Name
TOLLIP
UniProt Entry Name
TOLIP_HUMAN
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Product Notes
The TOLLIP tollip (Catalog #AAA45484) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Tollip antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Tollip can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TOLLIP tollip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tollip, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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