WB (Western Blot)
(Western blot analysis of extracts of various cell lines using TRAF2 Polyclonal Antibody at 1:1000 dilution.)
Rabbit anti-Human TRAF2 Polyclonal Antibody | anti-TRAF2 antibody
TRAF2 Polyclonal Antibody
Gene Names
TRAF2; TRAP; TRAP3; MGC:45012
Reactivity
Human
Applications
Western Blot
Purity
Affinity purification
Synonyms
TRAF2, Antibody; TRAF2 Polyclonal Antibody; TRAF2; MGC:45012; TRAP; TRAP3; TNF receptor-associated factor 2; anti-TRAF2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-TRAF2 antibody
WB (Western Blot)
Immunogen
Recombinant fusion protein of human TRAF2
Research Area
Cancer, Cell Biology, Cardiovascular, Signal Transduction
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using TRAF2 Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using TRAF2 Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of mouse thymus using TRAF2 Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of mouse thymus using TRAF2 Polyclonal Antibody at 1:1000 dilution.)
Related Product Information for anti-TRAF2 antibody
The protein encoded by this gene is member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.
Product Categories/Family for anti-TRAF2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,859 Da
NCBI Official Full Name
TNF receptor-associated factor 2
NCBI Official Synonym Full Names
TNF receptor-associated factor 2
NCBI Official Symbol
TRAF2
NCBI Official Synonym Symbols
TRAP; TRAP3; MGC:45012
NCBI Protein Information
TNF receptor-associated factor 2; E3 ubiquitin-protein ligase TRAF2; tumor necrosis factor type 2 receptor associated protein 3; tumor necrosis factor type 2 receptor-associated protein 3
UniProt Protein Name
TNF receptor-associated factor 2
UniProt Gene Name
TRAF2
UniProt Synonym Gene Names
TRAP3
UniProt Entry Name
TRAF2_HUMAN
Similar Products
Product Notes
The TRAF2 traf2 (Catalog #AAA179346) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRAF2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRAF2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the TRAF2 traf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRAF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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