IF (Immunofluorescence)
(Immunofluorescence of TRIM5 alpha in human breast tissue with TRIM5 alpha antibody at 10 ug/mL.)
Rabbit anti-Human TRIM5 alpha Polyclonal Antibody | anti-TRIM5 alpha antibody
TRIM5 alpha Antibody
Gene Names
TRIM5; RNF88; TRIM5alpha
Reactivity
Human
Applications
Immunofluorescence, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
TRIM5 alpha, Antibody; TRIM5 alpha Antibody; TRIM5a; anti-TRIM5 alpha antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Anti-TRIM5 alpha is human specific but should presumably also react with rhesus protein.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
493
Applicable Applications for anti-TRIM5 alpha antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a synthetic peptide corresponding to amino acids near the C-terminus of rhesus monkey TRIM5 alpha.
Target Name
TRIM5 alpha
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of TRIM5 alpha in human breast tissue with TRIM5 alpha antibody at 10 ug/mL.)
IF (Immunofluorescence)
(Immunofluorescence of TRIM5 alpha in human breast tissue with TRIM5 alpha antibody at 10 ug/mL.)
WB (Western Blot)
(Western blot analysis of TRIM5 alpha expression in human stomach (A), thymus (B), and uterus (C) cell lysate with TRIM5 alpha antibody at 2 ug /ml.)
WB (Western Blot)
(Western blot analysis of TRIM5 alpha expression in human stomach (A), thymus (B), and uterus (C) cell lysate with TRIM5 alpha antibody at 2 ug /ml.)
Related Product Information for anti-TRIM5 alpha antibody
TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. Expression of TRIM5a variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. All TRIM5a variants could inhibit at least two different retroviruses, but not from those viruses isolated from the same species, suggesting that TRIM5a acts as a natural barrier to cross-species retrovirus transmission.
Product Categories/Family for anti-TRIM5 alpha antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,677 Da
NCBI Official Full Name
tripartite motif-containing protein 5 isoform alpha
NCBI Official Synonym Full Names
tripartite motif containing 5
NCBI Official Symbol
TRIM5
NCBI Official Synonym Symbols
RNF88; TRIM5alpha
NCBI Protein Information
tripartite motif-containing protein 5
UniProt Protein Name
Tripartite motif-containing protein 5
UniProt Gene Name
TRIM5
UniProt Synonym Gene Names
RNF88
UniProt Entry Name
TRIM5_HUMAN
Similar Products
Product Notes
The TRIM5 alpha trim5 (Catalog #AAA302497) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRIM5 alpha Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRIM5 alpha can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TRIM5 alpha trim5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRIM5 alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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