Rabbit anti-Human TRIM5 gamma Polyclonal Antibody | anti-TRIM5 antibody

TRIM5 gamma Antibody

Cat. Num. AAA39225

• Gene Names: TRIM5; RNF88; TRIM5alpha
• Reactivity: Human
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: TRIM5 gamma Antibody is affinity chromatography purified via peptide column.
• Synonyms: TRIM5 gamma, Antibody; TRIM5 gamma Antibody; TRIM5 gamma; RNF88; TRIM5alpha; Tripartite motif-containing protein 5; RING finger protein 88; tripartite motif-containing 5; anti-TRIM5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: TRIM5 gamma Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 347

• Applicable Applications for anti-TRIM5 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: TRIM5 gamma antibody was raised against a synthetic peptide corresponding to 15 amino acids near the carboxy terminus of human TRIM5 gamma.
• Buffer: TRIM5 gamma Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: TRIM5 gamma antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of TRIM5 gamma in human bladder tissue with TRIM5 gamma antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of TRIM5 gamma in human bladder tissue with TRIM5 gamma antibody at 2 μg/mL.)

WB (Western Blot)

(Western blot analysis of TRIM5 gamma expression in human bladder (A) and colon (B) cell lysate with TRIM5 gamma antibody at 2 μg /ml.)

Related Product Information for anti-TRIM5 antibody

TRIM5 gamma Antibody: TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has five alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. While a function has not yet been assigned to TRIM5gamma, it is known that expression of TRIM5α variants from humans, rhesus monkeys, and African green monkeys enable resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. Furthermore, the TRIM5δ isoform appears to serve as a scaffold for the assembly of endogenous BTBD1 and BTBD2 proteins and also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner.

NCBI and Uniprot Product Information

• NCBI GI #: 15011944
• NCBI GeneID: 85363
• NCBI Accession #: NP_149083
• NCBI GenBank Nucleotide #: NM_033092.1
• UniProt Accession #: Q9C035; Q2MLV4; Q2MLV8; Q2MLV9; Q2MLW1; Q2MLW3; Q2MLW4; A6NGQ1; A8WFA8; D3DQS8; D3DQS9; G3GJY1
• Molecular Weight: 29,677 Da
• NCBI Official Full Name: tripartite motif protein TRIM5 isoform gamma
• NCBI Official Synonym Full Names: tripartite motif containing 5
• NCBI Official Symbol: TRIM5
• NCBI Official Synonym Symbols: RNF88; TRIM5alpha
• NCBI Protein Information: tripartite motif-containing protein 5; ring finger protein 88; tripartite motif protein TRIM5; tripartite motif containing 5 transcript variant iota; tripartite motif containing 5 transcript variant kappa
• UniProt Protein Name: Tripartite motif-containing protein 5
• UniProt Gene Name: TRIM5
• UniProt Synonym Gene Names: RNF88
• UniProt Entry Name: TRIM5_HUMAN