IF (Immunofluorescence)
(Immunofluorescence of XAF-1 in Human Spleen cells with XAF-1 antibody at 20 μg/mL.)
Rabbit anti-Human XAF-1 Polyclonal Antibody | anti-XAF1 antibody
XAF-1 Antibody
Gene Names
XAF1; BIRC4BP; XIAPAF1; HSXIAPAF1
Reactivity
Human
Applications
Immunofluorescence, Western Blot, ELISA
Purity
XAF-1 Antibody is affinity chromatography purified via peptide column.
Synonyms
XAF-1, Antibody; XAF-1 Antibody; XAF-1; BIRC4BP; XIAPAF1; HSXIAPAF1; XIAP-associated factor 1; BIRC4-binding protein; XIAP associated factor 1; anti-XAF1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
XAF-1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
317
Applicable Applications for anti-XAF1 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
XAF-1 antibody was raised against a synthetic peptide corresponding to 16 amino acids near the middle of human XAF-1.
Buffer
XAF-1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
XAF-1antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of XAF-1 in Human Spleen cells with XAF-1 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of XAF-1 in Human Spleen cells with XAF-1 antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of XAF-1 in human brain tissue lysate with XAF-1 antibody at (A) 0.5 and (B) 1 μg/mL..)
WB (Western Blot)
(Western blot analysis of XAF-1 in human brain tissue lysate with XAF-1 antibody at (A) 0.5 and (B) 1 μg/mL..)
Related Product Information for anti-XAF1 antibody
XAF-1 Antibody: XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, and -9, and triggers its relocation from the cytosol to the nucleus. Overexpression of XAF-1 results in the neutralization of XIAP's ability to inhibit cell death. XAF-1 is normally expressed in all adult and fetal tissues but was found to be present in very low levels in a variety of cancer cell lines. In contrast, XIAP levels have been shown to be high in a majority of cell lines. Low XAF-1 and high basal expression of XIAP may therefore play a critical role in maintaining survival of cancer cell lines. Both IFN-alpha2 and IFN-beta can induce XAF-1 mRNA in all cells examined but induction of XAF-1 protein (as observed by immunoblot analysis) was seen only in cell lines sensitive to the apoptotic effects of IFNs.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
34,543 Da
NCBI Official Full Name
XIAP associated factor-1 (ZAP-1)
NCBI Official Synonym Full Names
XIAP associated factor 1
NCBI Official Symbol
XAF1
NCBI Official Synonym Symbols
BIRC4BP; XIAPAF1; HSXIAPAF1
NCBI Protein Information
XIAP-associated factor 1; BIRC4 binding protein; BIRC4-binding protein
UniProt Protein Name
XIAP-associated factor 1
UniProt Gene Name
XAF1
UniProt Synonym Gene Names
BIRC4BP; XIAPAF1
UniProt Entry Name
XAF1_HUMAN
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Product Notes
The XAF1 xaf1 (Catalog #AAA39782) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XAF-1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's XAF-1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the XAF1 xaf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "XAF-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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