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product-image-AAA62233_AD11.jpg Application Data (Figure 3. Pseudoviral Particle (PP) Infection assays(SARS-CoV-2-Lambda variant pseudoviral particles on HEK293-ACE2 cells)Legends: SARS-2-CoV-Lambda: SARS-CoV-2 Lambda variant MLV Pseudovirus Particles (SCV2-PsV-Lambda)(-): MLV control (w/o envelope spike protein))

SARS-CoV-2 Pseudoviral Particles, Lambda Variant (Lineage C.37) Pseudovirus

SARS-CoV-2 Pseudoviral Particles, Lambda Variant (Lineage C.37)

Synonyms
SARS-CoV-2 Pseudoviral Particles, Lambda Variant (Lineage C.37); N/A; SARS-CoV-2 Pseudoviral Particles, Lambda Variant (Lineage C.37) pseudovirus
Ordering
Form/Format
10 ml (2 tubes, 5 mL/tube), for 2 multi-well plates
Features
Robust: Excellent signal to noise (basal) ratio
Easy to use: Amenable to HTS format (96-well, 384-well and 1536-well format)
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Upon receiving it, store at -70 degree C right away. Thaw before immediate use (Do not aliquot and refreeze). Shelf Life: Six months from the date of shipping when stored at -70 degree C

Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.

Shipping Note: Product is available for shipment in the United States, Canada and European countries. Please inquire for shipment to other countries.

Application Data

(Figure 3. Pseudoviral Particle (PP) Infection assays(SARS-CoV-2-Lambda variant pseudoviral particles on HEK293-ACE2 cells)Legends: SARS-2-CoV-Lambda: SARS-CoV-2 Lambda variant MLV Pseudovirus Particles (SCV2-PsV-Lambda)(-): MLV control (w/o envelope spike protein))

product-image-AAA62233_AD11.jpg Application Data (Figure 3. Pseudoviral Particle (PP) Infection assays(SARS-CoV-2-Lambda variant pseudoviral particles on HEK293-ACE2 cells)Legends: SARS-2-CoV-Lambda: SARS-CoV-2 Lambda variant MLV Pseudovirus Particles (SCV2-PsV-Lambda)(-): MLV control (w/o envelope spike protein))

Gene Sequence

(Figure 2. Protein sequence of the Lambda spike in SCV2-PsV-Lambda pseudoviral particles)

product-image-AAA62233_SEQUENCE13.jpg Gene Sequence (Figure 2. Protein sequence of the Lambda spike in SCV2-PsV-Lambda pseudoviral particles)

Application Data

(Figure 1. Illustration of the replication-deficient MLV particle pseudotyped with SARS-CoV-2 Spike protein)

product-image-AAA62233_AD15.jpg Application Data (Figure 1. Illustration of the replication-deficient MLV particle pseudotyped with SARS-CoV-2 Spike protein)
Related Product Information for SARS-CoV-2 Pseudoviral Particles, Lambda Variant (Lineage C.37) pseudovirus
It has been known that SARS coronavirus 2 (SARS-CoV-2) uses human ACE2 as entry receptor and human proteases as entry activators. The virus surface spike protein (S) mediates SARS-CoV-2 entry into cells. To fulfill its function, SARS-CoV-2 spike binds to its human ACE2 (hACE2) receptor through its receptor-binding domain (RBD) and is proteolytically activated by human proteases.

Our SARS-CoV-2-Lambda Pseudoviral Particles are replication-deficient MLV pseudotyped with the SARS-CoV-2 spike protein (Accession ID: EPI_ISL_3274616) of the Lamdba variant, originally known as lineage C.37. They also contain the ORF for firefly luciferase as a reporter. They establish a pseudovirus cell entry assay mediated by the SARS-CoV-2 spike protein that can be conveniently measured via luciferase reporter activity. This pseudovirus assay isolates the SARS-CoV-2 viral entry from other steps of the viral infection cycle.

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Product Notes

The SARS-CoV-2 Pseudoviral Particles, Lambda Variant (Lineage C.37) (Catalog #AAA62233) is a Pseudovirus and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SARS-CoV-2 Pseudoviral Particles, Lambda Variant (Lineage C.37), Pseudovirus" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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