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product-image-AAA174596_SDS_PAGE15.jpg SDS-PAGE

Nogo-66 Receptor/Reticulon 4 Receptor Recombinant Protein | RTN4R recombinant protein

Recombinant Human Nogo-66 Receptor/Reticulon 4 Receptor Protein

Gene Names
RTN4R; NGR; NOGOR
Purity
> 95 % as determined by reducing SDS-PAGE.
Synonyms
Nogo-66 Receptor/Reticulon 4 Receptor; N/A; Recombinant Human Nogo-66 Receptor/Reticulon 4 Receptor Protein; Reticulon-4 Receptor; Nogo Receptor; NgR; Nogo-66 Receptor; RTN4R; NOGOR; RTN4R recombinant protein
Ordering
Host
Human Cells
Purity/Purification
> 95 % as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Sequence Positions
Cys27-Ser447
Species
Human
Tag
C-6His
Endotoxin
< 1.0 EU per ?g as determined by the LAL method.
Reconstitution
We recommend that the vial be centrifuged to opening to bring the contents to the bottom. Do not mix by vortex. It is recommended that sterile water(200?l) be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV-Vis.
Preparation and Storage
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C.
Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

SDS-PAGE

product-image-AAA174596_SDS_PAGE15.jpg SDS-PAGE
Related Product Information for RTN4R recombinant protein
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Mol_Mass: 46.3 kDa
AP_Mol_Mass: 60-90 kDa
NCBI Official Full Name
reticulon-4 receptor
NCBI Official Synonym Full Names
reticulon 4 receptor
NCBI Official Symbol
RTN4R
NCBI Official Synonym Symbols
NGR; NOGOR
NCBI Protein Information
reticulon-4 receptor
UniProt Protein Name
Reticulon-4 receptor
UniProt Gene Name
RTN4R
UniProt Synonym Gene Names
NOGOR; NgR

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Product Notes

The RTN4R rtn4r (Catalog #AAA174596) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Cys27-Ser447. It is sometimes possible for the material contained within the vial of "Nogo-66 Receptor/Reticulon 4 Receptor, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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