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AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 600-650 of 2567 product results
Bioactivity
(Figure 2. Inhibition of A549 cells proliferation after stimulated with TNF-beta.)
Tumor Necrosis Factor Beta (TNFb), Active Protein (Cat# AAA152995)
Full Name
Active Tumor Necrosis Factor Beta (TNFb)
Gene Names
LTA; TNFB
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Plasminogen Activator, Urokinase Receptor (uPAR) is the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasmi)
Plasminogen Activator, Urokinase Receptor (uPAR), Active Protein (Cat# AAA152998)
Full Name
Active Plasminogen Activator, Urokinase Receptor (uPAR)
Gene Names
Plaur; Cd87; uPAR; u-PAR
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. The hemagglutination assay of GAL4 in V- bottom shaped 96-well microtiter plate.)
Galectin 4 (GAL4), Active Protein (Cat# AAA153017)
Full Name
Active Galectin 4 (GAL4)
Gene Names
Lgals4; gal-4
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. The hemagglutination assay of GAL4 in V- bottom shaped 96-well microtiter plate.)
Galectin 4 (GAL4), Active Protein (Cat# AAA153018)
Full Name
Active Galectin 4 (GAL4)
Gene Names
LGALS4; L36LBP
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. The hemagglutination assay of GAL4 in V- bottom shaped 96-well microtiter plate.)
Galectin 4 (GAL4), Active Protein (Cat# AAA153019)
Full Name
Active Galectin 4 (GAL4)
Gene Names
Lgals4; L-36; L36LBI
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(The galectins constitute a large family of carbohydrate-binding proteins with specificity for N-acetyl-lactosamine-containing glycoproteins. At least 14 mammalian galectins, which share structural similarities in their carbohydrate recognition domains (CR)
Galectin 7 (GAL7), Active Protein (Cat# AAA153021)
Full Name
Active Galectin 7 (GAL7)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
Bioactivity
(Galectin 9 (GAL9) is a member of the beta-galactoside-binding galectin family. Galectin-9 is found outside of cells and may be exported by non-classical pathways. Galectin 9 exhibits a variety of biological activities, the majority of which have focused o)
Galectin 9 (GAL9), Active Protein (Cat# AAA153025)
Full Name
Active Galectin 9 (GAL9)
Gene Names
Lgals9; gal-9; Lgals5; LGALS35; AA407335; AI194909; AI265545; galectin-9
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. The hemagglutination assay of GAL12 in V- bottom shaped 96-well microtiter plate.)
Galectin 12 (GAL12), Active Protein (Cat# AAA153029)
Full Name
Active Galectin 12 (GAL12)
Applications
Activity Assay, Cell Culture
Purity
Greater than 80% by SDS-PAGE
Pricing
Bioactivity
(Luteinizing Hormone (LH) is a 42 kDa heterodimer belonging to the glycoprotein hormone family. It is composed of noncovalently linked glycosylated alpha and beta chains. The alpha subunit (CG alpha ) is also a component of Follicle-Stimulating Hormone (FS)
Luteinizing Hormone (LH), Active Protein (Cat# AAA153035)
Full Name
Active Luteinizing Hormone (LH)
Gene Names
UCP1; UCP; SLC25A7
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Interleukin 1 beta (IL-1beta) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a member of the interleukin 1 family of cytokines. This cytokine is an important medi)
Interleukin 1 Beta (IL1b), Active Protein (Cat# AAA153041)
Full Name
Active Interleukin 1 Beta (IL1b)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Caspase 3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at co)
Caspase 3 (CASP3), Active Protein (Cat# AAA153051)
Full Name
Active Caspase 3 (CASP3)
Gene Names
Casp3; Lice; Yama; CPP32-beta
Applications
Activity Assay, Cell Culture
Purity
Greater than 80% by SDS-PAGE
Pricing
Bioactivity
(TLR4 is a 100 kDa type I transmembrane glycoprotein that belongs to the mammalian Toll-Like Receptor family of pathogen pattern recognition molecules. TLRs plays a fundamental role in pathogen recognition and activation of innate immunity. Besides, TLR4 i)
Toll Like Receptor 4 (TLR4), Active Protein (Cat# AAA153056)
Full Name
Active Toll Like Receptor 4 (TLR4)
Gene Names
TLR4; TOLL; CD284; TLR-4; ARMD10
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(TLR4 is a 100 kDa type I transmembrane glycoprotein that belongs to the mammalian Toll-Like Receptor family of pathogen pattern recognition molecules. TLRs plays a fundamental role in pathogen recognition and activation of innate immunity. Besides, TLR4 i)
Toll Like Receptor 4 (TLR4), Active Protein (Cat# AAA153057)
Full Name
Active Toll Like Receptor 4 (TLR4)
Gene Names
TLR4; TOLL; CD284; TLR-4; ARMD10
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, whose levels rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages a)
C ReProtein (CRP), Active Protein (Cat# AAA153061)
Full Name
Active C Reactive Protein (CRP)
Gene Names
Crp; Aa1249; Ac1262; Ab1-341; Ab2-196; Ac1-114; Ac2-069; Ba2-693
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Neurosecretory protein VGF is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The protein shares similarities with the secretogranin/chromogranin family, however, its exact function is not know)
VGF Nerve Growth Factor Inducible (VGF), Active Protein (Cat# AAA153076)
Full Name
Active VGF Nerve Growth Factor Inducible (VGF)
Gene Names
Vgf; Gm1052
Applications
Activity Assay, Cell Culture
Purity
Greater than 80% by SDS-PAGE
Pricing
Bioactivity
(Neurosecretory protein VGF is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The protein shares similarities with the secretogranin/chromogranin family, however, its exact function is not know)
VGF Nerve Growth Factor Inducible (VGF), Active Protein (Cat# AAA153077)
Full Name
Active VGF Nerve Growth Factor Inducible (VGF)
Gene Names
Vgf; Gm1052
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(B-Lymphocyte Activation Antigen B7-1 (CD80) is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B)
B-Lymphocyte Activation Antigen B7-1 (LAB7-1), Active Protein (Cat# AAA153083)
Full Name
Active B-Lymphocyte Activation Antigen B7-1 (LAB7-1)
Gene Names
CD80; B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), was originally identified as a component of neutrophil granules. It is a 25 kDa protein existing in monomeric and homo- and heterodimeric forms, the latter as a dimer with human)
Neutrophil gelatinase-associated lipocalin (NGAL), Active Protein (Cat# AAA153086)
Full Name
Active Neutrophil gelatinase-associated lipocalin (NGAL)
Gene Names
Lcn2; 24p3; Sip24; AW212229
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Interleukin 3 receptor alpha (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a subunit of the functional high-affinity human IL-3 receptor which is a heterodimer. The alpha subunit alone binds IL-3 with low affinity. The beta subunit doe)
Interleukin 3 Receptor Alpha (IL3Ra), Active Protein (Cat# AAA153090)
Full Name
Active Interleukin 3 Receptor Alpha (IL3Ra)
Gene Names
IL3RA; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
SDS-PAGE
(Sample: Active recombinant GNLY, Human)
Granulysin (GNLY), Active Protein (Cat# AAA153093)
Full Name
Active Granulysin (GNLY)
Gene Names
GNLY; 519; LAG2; NKG5; LAG-2; D2S69E; TLA519
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>80%
Pricing
Bioactivity
(Extracellular matrix metalloproteinase (MMP) inducer (EMMPRIN), also known as basigin and CD147, is a 4466 kDa, variably N and Oglycosylated, type I transmembrane protein that belongs to the immunoglobulin superfamily. Human EMMPRIN is 269 amino acids (aa)
Cluster Of Differentiation 147 (CD147), Active Protein (Cat# AAA153095)
Full Name
Active Cluster Of Differentiation 147 (CD147)
Gene Names
BSG; M6; OK; 5F7; TCSF; CD147; EMMPRIN
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Sonic Hedgehog (Shh) is expressed in embryonic tissues that are critical for the patterning of the developing central nervous system, somite, and limb. It is also involved in whisker, hair, foregut, tooth, and bone development. Shh regulates neural and he)
Hedgehog Homolog, Sonic (SHH), Active Protein (Cat# AAA153105)
Full Name
Active Hedgehog Homolog, Sonic (SHH)
Gene Names
SHH; TPT; HHG1; HLP3; HPE3; SMMCI; TPTPS; MCOPCB5
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
Bioactivity
(Extracellular superoxide dismutase [Cu-Zn] is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide r)
Superoxide Dismutase 1 (SOD1), Active Protein (Cat# AAA153107)
Full Name
Active Superoxide Dismutase 1 (SOD1)
Gene Names
Sod1; Ipo1; SODC; Ipo-1; Sod-1; CuZnSOD; Cu/Zn-SOD; MGC107553; B430204E11Rik; Sod1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Interleukin-29 (IL-29) is a member of the helical cytokine family and is a type III interferon. It is also known as IFNlambda1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon. IL-29 plays an important role in host)
Interleukin 29 (IL29), Active Protein (Cat# AAA153110)
Full Name
Active Interleukin 29 (IL29)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(DHCR7 (7-dehydrocholesterol reductase) is a rate-limiting enzyme in cholesterol synthesis, which is mainly involved in the conversion of 7-dehydrocholesterol (7-DHC) to cholesterol. In the cholesterol biosynthetic pathway, this protease can reduce the C7-)
7-Dehydrocholesterol Reductase (DHCR7), Active Protein (Cat# AAA153112)
Full Name
Active 7-Dehydrocholesterol Reductase (DHCR7)
Gene Names
DHCR7; SLOS
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Carbonic Anhydrase IX (CA9) also known as membrane antigen MN and renal cell carcinoma (RCC) associated antigen G250, is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. rhCA9 correspond)
Carbonic Anhydrase IX (CA9), Active Protein (Cat# AAA153125)
Full Name
Active Carbonic Anhydrase IX (CA9)
Gene Names
CA9; MN; CAIX
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Interleukin 37, also known as Interleukin 1 Zeta (IL1z), is an anti-inflammatory cytokine. Interleukines are cytokines that make an important part of immune signaling. It belongs to the interleukin-1 family. IL-37 plays a role in protecting the body again)
Interleukin 1 Zeta (IL1z), Active Protein (Cat# AAA153128)
Full Name
Active Interleukin 1 Zeta (IL1z)
Gene Names
IL37; FIL1; FIL1Z; IL-1H; IL-37; IL1F7; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1; FIL1(ZETA)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(IL36G (Interleukin 36 gamma), also known as IL-1F9 and IL-1H1 is a member of the IL-1 family of cytokines. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferati)
Interleukin 1 Family, Member 9 (IL1F9), Active Protein (Cat# AAA153138)
Full Name
Active Interleukin 1 Family, Member 9 (IL1F9)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Application Data
IL22, Active Protein (Cat# AAA214257)
Full Name
Recombinant Human IL22
Gene Names
IL22; TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; TIFIL-23
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
GMFB, Active Protein (Cat# AAA214263)
Full Name
Recombinant Human GMFB
Gene Names
GMFB; GMF
Purity
>95% as determined by SDS-PAGE
Pricing
SDS-PAGE
Carbonic Anhydrase IX / CA9, Active Protein (Cat# AAA173576)
Full Name
Recombinant Human Carbonic Anhydrase IX / CA9 Protein (His tag)
Gene Names
CA9; MN; CAIX
Purity
> 95 % as determined by SDS-PAGE
Pricing
SDS-PAGE
IL1R1 / CD121a, Active Protein (Cat# AAA173585)
Full Name
Recombinant Mouse IL1R1 / CD121a Protein (His tag)
Gene Names
Il1r1; IL-iR; CD121a; CD121b; IL-1R1; Il1r-1
Purity
> 95 % as determined by SDS-PAGE
Pricing
Bioactivity
Tumor-associated Calcium Signal Transducer 2/TROP-2, Active Protein (Cat# AAA177964)
Full Name
Recombinant Human Tumor-associated Calcium Signal Transducer 2/TROP-2 (248AA, C-Fc)
Gene Names
TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Application Data
Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF), Active Protein (Cat# AAA146599)
Full Name
Active Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF)
Gene Names
Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
Application Data
Interferon Gamma (IFNg), Active Protein (Cat# AAA146602)
Full Name
Active Interferon Gamma (IFNg)
Gene Names
Ifng; Ifg; IFN-g
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Application Data
Macrophage Inflammatory Protein 1 Alpha (MIP1a), Active Protein (Cat# AAA146611)
Full Name
Active Macrophage Inflammatory Protein 1 Alpha (MIP1a)
Gene Names
CCL3; MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
SDS-PAGE
Matrix Metalloproteinase 2 (MMP2), Active Protein (Cat# AAA146612)
Full Name
Active Matrix Metalloproteinase 2 (MMP2)
Gene Names
MMP2; CLG4; MONA; CLG4A; MMP-2; TBE-1; MMP-II
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>98%
Pricing
Application Data
Insulin (INS), Active Protein (Cat# AAA146619)
Full Name
Active Insulin (INS)
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
Interleukin 17 Receptor C (IL17RC), Active Protein (Cat# AAA148123)
Full Name
Active Interleukin 17 Receptor C (IL17RC)
Gene Names
IL17RC; CANDF9; IL17RL; IL17-RL
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
V-Myc Myelocytomatosis Viral Oncogene Homolog (MYC), Active Protein (Cat# AAA148128)
Full Name
Active V-Myc Myelocytomatosis Viral Oncogene Homolog (MYC)
Gene Names
MYC; MRTL; MYCC; c-Myc; bHLHe39
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
Neuraminidase (NEU), Active Protein (Cat# AAA148148)
Full Name
Active Neuraminidase (NEU)
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
Bioactivity
(Figure 2. Cell proliferation of 3T3 cells after stimulated with AGE.)
Advanced Glycation End Product (AGE), Active Protein (Cat# AAA148250)
Full Name
Active Advanced Glycation End Product (AGE)
Applications
Activity Assay, Cell Culture
Purity
Purity: >90% as determined by SDS-PAGE.
Purification Methods: Salt co-precipitation and ionic-Exchange chromatography.
Purification Methods: Salt co-precipitation and ionic-Exchange chromatography.
Pricing
Bioactivity
(Figure 2. Inhibition of A549 cells proliferation after stimulated with IFN-.)
Interferon Alpha, Active Protein (Cat# AAA150049)
Full Name
Active Interferon Alpha (IFNa)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Application Data
(Figure. The chemotactic effect of recombinant human MIP1-on Jurkat cells.)
Macrophage Inflammatory Protein 1 Beta, Active Protein (Cat# AAA150067)
Full Name
Active Macrophage Inflammatory Protein 1 Beta (MIP1b)
Gene Names
CCL4; ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
Bioactivity
(Figure. The binding activity of TIMP3 with MMP2.Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) is an protein belongs to the tissue inhibitor of metalloproteinases family. They are inhibitors of the matrix metalloproteinases. TIMP-3 is the only member of the TIMP family which is found exclusively in the extracellular matrix (ECM). It is regulated in a cell cycle-dependent fashion in certain cell types and may serve as a marker for terminal differentiation. Besides, Matrix Metalloproteinase 2 (MMP2) has been identified as an interactor of TIMP3, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse TIMP3 and recombinant mouse MMP2. Briefly, TIMP3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100ul were then transferred to MMP2-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-TIMP3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of TIMP3 and MMP2 was shown in Figure 1, and this effect was in a dose dependent manner.)
Tissue Inhibitors Of Metalloproteinase 3, Active Protein (Cat# AAA150076)
Full Name
Active Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
Gene Names
Timp3; Timp-3
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
Bioactivity
(Figure. The binding activity of IL1b with IL1R1.)
Interleukin 1 Beta, Active Protein (Cat# AAA150094)
Full Name
Active Interleukin 1 Beta (IL1b)
Gene Names
Il1b; IL-1F2
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
WB (Western Blot)
(Western Blot Sample: Recombinant PIIINP, Human;Antibody: Rabbit Anti-Human PIIINP Ab)
Procollagen III N-Terminal Propeptide, Active Protein (Cat# AAA150095)
Full Name
Active Procollagen III N-Terminal Propeptide (PIIINP)
Gene Names
COL3A1; EDS4A; EDSVASC; PMGEDSV
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>98%
Pricing
Bioactivity
(Myostatin (MSTN) also known as growth differentiation factor 8 (GDF-8) is a member of the TGF beta protein family. Myostatin is a secreted growth differentiation factor that produced and released by myocytes. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Besides, Bone Morphogenetic Protein 1 (BMP1) has been identified as an interactor of MSTN, thus a binding ELISA assay was conducted to detect the interaction of recombinant human MSTN and recombinant human BMP1. Briefly, MSTN were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to BMP1-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-MSTN pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of MSTN and BMP1 was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of MSTN with BMP1.)
Myostatin, Active Protein (Cat# AAA150112)
Full Name
Active Myostatin (MSTN)
Gene Names
MSTN; GDF8; MSLHP
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Application Data
(Semaphorin-3F (SEMA3F) is a member of semaphorins family. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues. Semaphorins not only guide axons in development, but also have major roles in immune function (classes 4, 6, and 7) and the development of bones. Class 3 semaphorins are one of the most versatile semaphorin classes, in which Sema3a is the most studied. Besides, SEMA3F is deleted or downregulated in many metastatic tumors. To test the effect of SEMA3F on inhibit cell proliferation, human lung carcinoma cells A549 were seeded into triplicate wells of 96-well plates at a density of 5,000 cells/well and allowed to attach, replaced with serum-free overnight, then the medium was replaced with 2% serum standard DMEM prior to the addition of various concentrations of recombinant human SEMA3F. After incubated for 48h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37. Proliferation of A549 cells after incubation with SEMA3F for 48h observed by inverted microscope was shown in Figure 1. Cell viability was assessed by CCK-8 assay after incubation with recombinant SEMA3F for 48h. The result was shown in Figure 2. It was obvious that SEMA3F significantly increased cell viability of A549 cells. (A) A549 cells cultured in DMEM, stimulated with 100ng/mL SEMA3F for 48h; (B) Unstimulated A549 cells cultured in DMEM for 48h.Figure. Cell proliferation of A549 cells inhibtion by stimulating with SEMA3F.)
Semaphorin 3F, Active Protein (Cat# AAA150147)
Full Name
Active Semaphorin 3F (SEMA3F)
Gene Names
SEMA3F; SEMA4; SEMAK; SEMA-IV
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
SDS-PAGE
(Figure. SDS-PAGE)
Fibroblast Growth Factor 10 (FGF10), Active Protein (Cat# AAA150560)
Full Name
Active Fibroblast Growth Factor 10 (FGF10)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.
All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Learn more in our guide “How active proteins work”.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.