Application Data
CXCL1 active protein
Recombinant Human CXCL1
Gene Names
CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
Purity
>95% as determined by SDS-PAGE
Synonyms
CXCL1; N/A; Recombinant Human CXCL1; Growth Regulated Protein; Melanoma Growth Stimulatory Activity; GRO-alpha; MGSA-alpha; NAP-3; GRO1; C-X-C motif chemokine 1; GRO-alpha(1-73); Recombinant Human Growth Regulated Alpha Protein (CXCL1); CXCL1 active protein
Host
E Coli
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from a 0.2 um filtered solution in 40 mM NaCl and PB, pH 7.0
Sequence Length
107
Bioactivity
Determined by the ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/mL
Endotoxin Level
<1.0 EU/ug of recombinant protein as determined by the LAL method
Species
Human (Homo sapiens)
Reconstitution
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Preparation and Storage
Store at -70°C. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid multiple freeze/thaw cycles.
Application Data
Application Data
Related Product Information for CXCL1 active protein
A chemokine, the growth regulated oncogene-alpha is identical with MGSA (melanoma growth stimulatory activity) with its new designation being CXCL1. The expression of GRO can be induced by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
8 kDa
NCBI Official Full Name
growth-regulated alpha protein
NCBI Official Synonym Full Names
C-X-C motif chemokine ligand 1
NCBI Official Symbol
CXCL1
NCBI Official Synonym Symbols
FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
NCBI Protein Information
growth-regulated alpha protein
UniProt Protein Name
Growth-regulated alpha protein
UniProt Gene Name
CXCL1
UniProt Synonym Gene Names
GRO; GRO1; GROA; MGSA; SCYB1; MGSA; NAP-3
UniProt Entry Name
GROA_HUMAN
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Product Notes
The CXCL1 cxcl1 (Catalog #AAA214223) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CXCL1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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