Human Alpha-1-Antichymotrypsin, SERPINA3 ELISA Kit | SERPINA3 elisa kit
Human Alpha-1-Antichymotrypsin, SERPINA3 Primacu ELISA Kit
Gene Names
SERPINA3; ACT; AACT; GIG24; GIG25
Reactivity
Human
Synonyms
Alpha-1-Antichymotrypsin, SERPINA3; N/A; Human Alpha-1-Antichymotrypsin, SERPINA3 Primacu ELISA Kit; Alpha-1-antichymotrypsin; SerpinA3; AACT; SERPINA3 elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
47-3000pg/mL
Sensitivity
13.47pg/mL
Standard Solution
30ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Related Product Information for SERPINA3 elisa kit
SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has been demonstrated to inhibit the activity of certain serine proteases, such as cathepsin G found in neutrophils, and chymases present in mast cells, by inducing a major conformational rearrangement, and thus protects some tissues from damage caused by proteolytic enzymes. This enzyme is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease, and mutations of this gene have been observed in patients with Parkinson disease and chronic obstructive pulmonary disease. Besides, ACT gene polymorphism has been implicated with Alzheimer's disease (AD), cerebral amyloid angiopathy (CAA), as well as stroke, since SerpinA3 is a major constituent of the plaques in AD and an inhibitor of amyloid beta peptide degradation.
Product Categories/Family for SERPINA3 elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
423
NCBI Official Full Name
Alpha-1-antichymotrypsin
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
NCBI Official Symbol
SERPINA3
NCBI Official Synonym Symbols
ACT; AACT; GIG24; GIG25
NCBI Protein Information
alpha-1-antichymotrypsin; serpin A3; growth-inhibiting protein 24; growth-inhibiting protein 25; cell growth-inhibiting gene 24/25 protein; serine (or cysteine) proteinase inhibitor, clade A, member 3
UniProt Protein Name
Alpha-1-antichymotrypsin
UniProt Gene Name
SERPINA3
UniProt Synonym Gene Names
AACT; ACT
UniProt Entry Name
AACT_HUMAN
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Product Notes
The Human SERPINA3 serpina3 (Catalog #AAA124201) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124201 ELISA Kit recognizes Human SERPINA3. It is sometimes possible for the material contained within the vial of "Alpha-1-Antichymotrypsin, SERPINA3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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