IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human liver stained with Alpha-1-Antichymotrypsin Mouse Monoclonal Antibody (SERPINA3/4190).)
Mouse anti-Human Alpha-1-Antichymotrypsin (SERPINA3) Monoclonal Antibody | anti-SERPINA3 antibody
Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) Mouse Monoclonal Antibody [Clone SERPINA3/4190]
Gene Names
SERPINA3; ACT; AACT; GIG24; GIG25
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
Alpha-1-Antichymotrypsin (SERPINA3), Antibody; Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) Mouse Monoclonal Antibody [Clone SERPINA3/4190]; Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker); AACT; ACT; Alpha-1-antichymotrypsin; Cell growth-inhibiting gene 24/25 protein; GIG24; GIG25; Growth inhibiting protein 24; Growth inhibiting protein 25; Serine (or cysteine) proteinase inhibitor clade A member 3; Serpin A3; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3; anti-SERPINA3 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG2b, kappa
Clone Number
SERPINA3/4190
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-SERPINA3 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant human Antichymotrypsin (AACT) protein fragment (around aa 49-187) (exact sequence is proprietary)
Cellular Localization
Cytoplasm
Positive Control
HeLa cells. Human tonsil, pancreas or histiocytoma.
Hu-chromosome Location
14q32.1
Unigene
534293; 710488
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human liver stained with Alpha-1-Antichymotrypsin Mouse Monoclonal Antibody (SERPINA3/4190).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human liver stained with Alpha-1-Antichymotrypsin Mouse Monoclonal Antibody (SERPINA3/4190).)
Related Product Information for anti-SERPINA3 antibody
It recognizes a protein of 65-76kDa, which is identified antichymotrypsin (AACT). AACT is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of alpha 1-antitrypsin (AAT), with which it shares nucleic acid and protein sequence homology. Both are major acute phase reactants; their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the identification of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACT antibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
423
NCBI Official Full Name
Alpha-1-antichymotrypsin
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
NCBI Official Symbol
SERPINA3
NCBI Official Synonym Symbols
ACT; AACT; GIG24; GIG25
NCBI Protein Information
alpha-1-antichymotrypsin; serpin A3; growth-inhibiting protein 24; growth-inhibiting protein 25; cell growth-inhibiting gene 24/25 protein; serine (or cysteine) proteinase inhibitor, clade A, member 3
UniProt Protein Name
Alpha-1-antichymotrypsin
UniProt Gene Name
SERPINA3
UniProt Synonym Gene Names
AACT; ACT
UniProt Entry Name
AACT_HUMAN
Similar Products
Product Notes
The SERPINA3 serpina3 (Catalog #AAA215562) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) Mouse Monoclonal Antibody [Clone SERPINA3/4190] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Alpha-1-Antichymotrypsin (SERPINA3) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the SERPINA3 serpina3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Alpha-1-Antichymotrypsin (SERPINA3), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.