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Alpha-1 AntiChymotrypsin Native Protein | SERPINA3 native protein

Human Alpha-1 AntiChymotrypsin

Gene Names
SERPINA3; ACT; AACT; GIG24; GIG25
Purity
Greater than 99.0%.
Synonyms
Alpha-1 AntiChymotrypsin; N/A; Human Alpha-1 AntiChymotrypsin; SERPINA3 Human; Alpha-1 AntiChymotrypsin Human; Alpha-1-antichymotrypsin; ACT; Cell growth-inhibiting gene 24/25 protein; SERPINA3; AACT; A1ACT; GIG24; GIG25; MGC88254; SERPINA3 native protein
Ordering
Host
Human Serum
Purity/Purification
Greater than 99.0%.
Form/Format
Lyophilized from 0.02M NH4HCO3.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence Length
423
Solubility
It is recommended to reconstitute the lyophilized human A1ACT in phosphate buffer pH > 7.0 containing 0.15M NaCl.
Human Virus Test
Starting material tested and found negative for HIV I & II antibodies, Hepatitis B surface antigen, and Hepatitis C antibodies.
Preparation and Storage
Human SERPINA3 although stable at room temperature for 3 weeks, should be stored between 2-8 degree C.
Related Product Information for SERPINA3 native protein
Description: Human Alpha-1 AntiChymotrypsin produced from normal human serum having a molecular mass of 68kDa.

Introduction: Alpha 1 ACT is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1- ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain.Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
Product Categories/Family for SERPINA3 native protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
12
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10,717 Da
NCBI Official Full Name
alpha-1-antichymotrypsin
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
NCBI Official Symbol
SERPINA3
NCBI Official Synonym Symbols
ACT; AACT; GIG24; GIG25
NCBI Protein Information
alpha-1-antichymotrypsin; cell growth-inhibiting gene 24/25 protein; growth-inhibiting protein 24; growth-inhibiting protein 25; serine (or cysteine) proteinase inhibitor, clade A, member 3; serpin A3
UniProt Protein Name
Alpha-1-antichymotrypsin
UniProt Gene Name
SERPINA3
UniProt Synonym Gene Names
AACT; ACT
UniProt Entry Name
AACT_HUMAN

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Product Notes

The SERPINA3 serpina3 (Catalog #AAA38462) is a Native Protein produced from Human Serum and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Alpha-1 AntiChymotrypsin, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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