IF (Immunofluorescence)
(Immunofluorescence analysis of Human stomach cancer tissue using Catenin-beta Monoclonal Antibody at dilution of 1:200.)
Mouse Catenin-beta Monoclonal Antibody | anti-CTNNB1 antibody
Catenin-beta Monoclonal Antibody
Gene Names
CTNNB1; EVR7; CTNNB; MRD19; armadillo
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Protein A Purification
Synonyms
Catenin-beta, Antibody; Catenin-beta Monoclonal Antibody; anti-CTNNB1 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
2E4
Purity/Purification
Protein A Purification
Concentration
1mg/mL (varies by lot)
Sequence Length
781
Applicable Applications for anti-CTNNB1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant Protein
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.4
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence analysis of Human stomach cancer tissue using Catenin-beta Monoclonal Antibody at dilution of 1:200.)
IF (Immunofluorescence)
(Immunofluorescence analysis of Human stomach cancer tissue using Catenin-beta Monoclonal Antibody at dilution of 1:200.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Mouse kidney tissue using Catenin-beta Monoclonal Antibody at dilution of 1:200.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Mouse kidney tissue using Catenin-beta Monoclonal Antibody at dilution of 1:200.)
WB (Western Blot)
(Western Blot analysis of 1) Hela, 2) 293T, 3) Mouse liver, 4) Rat liver with Catenin-beta Monoclonal Antibody.)
WB (Western Blot)
(Western Blot analysis of 1) Hela, 2) 293T, 3) Mouse liver, 4) Rat liver with Catenin-beta Monoclonal Antibody.)
Related Product Information for anti-CTNNB1 antibody
Key dowstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes.Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
Product Categories/Family for anti-CTNNB1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
92kDa
NCBI Official Full Name
Catenin beta-1
NCBI Official Synonym Full Names
catenin beta 1
NCBI Official Symbol
CTNNB1
NCBI Official Synonym Symbols
EVR7; CTNNB; MRD19; armadillo
NCBI Protein Information
catenin beta-1
UniProt Protein Name
Catenin beta-1
UniProt Gene Name
CTNNB1
UniProt Synonym Gene Names
CTNNB
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Product Notes
The CTNNB1 ctnnb1 (Catalog #AAA173651) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Catenin-beta Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Catenin-beta can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CTNNB1 ctnnb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Catenin-beta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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