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product-image-AAA215420_IHC13.jpg IHC (Immunohiostchemistry) (Formalin-fixed, paraffin-embedded human tonsil stained with Collagen IV Recombinant Rabbit Monoclonal Antibody (COL4/4241R).)

Rabbit anti-Human Collagen IV Monoclonal Antibody | anti-COL4A antibody

Collagen IV

Reactivity
Human
Applications
Immunohistochemistry
Purity
Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Synonyms
Collagen IV, Antibody; Collagen IV; Arresten; BSVD; COL4A1; COL4A1 NC1 domain; COL4A2; COL4A3; COL4A4; COL4A5; collagen alpha-1(IV) chain; Collagen IV Alpha 1 Polypeptide; Collagen IV Alpha 2 Polypeptide; Collagen Type IV Alpha 2; Collagen Type IV Alpha 3; Collagen Type IV Alpha 4; Collagen Type IV Alpha 5; RATOR; anti-COL4A antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
COL4/4241R
Specificity
Collagen Type IV is a major component of the basement membrane and plays an important role in cell adhesion, migration, differentiation and growth. Collagen Type IV express at the basement membranes in a variety of tissues including kidney, muscle, lymph nodes, lung, tendon and spleen. Collagen Type IV has been shown to be useful in differentiating microinvasive from in situ ductal carcinomas of the breast. Other Collagen Type IV studies include use in pancreatic adenocarcinoma and chronic pancreatitis, nephrosclerosis and other kidney diseases, oral squamous cell carcinoma, laryngeal cancers, ovarian cancers and cervical cancers.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
1669
Applicable Applications for anti-COL4A antibody
IHC (Immunohistochemistry)
Immunogen
Purified Human placental extract
Cellular Localization
Secreted Extracellular Matrix
Antibody Type
Recombinant Antibody
Hu-chromosome Location
13q34 (COL4A1 COL4A2); 2q36.3 (COL4A3 COL4A4); Xq22.3 (COL4A5)
Positive Control
Human placenta or Tonsil.
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohiostchemistry)

(Formalin-fixed, paraffin-embedded human tonsil stained with Collagen IV Recombinant Rabbit Monoclonal Antibody (COL4/4241R).)

product-image-AAA215420_IHC13.jpg IHC (Immunohiostchemistry) (Formalin-fixed, paraffin-embedded human tonsil stained with Collagen IV Recombinant Rabbit Monoclonal Antibody (COL4/4241R).)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human tonsil stained with Collagen IV Recombinant Rabbit Monoclonal Antibody (COL4/4241R).)

product-image-AAA215420_IHC15.jpg IHC (Immunohistochemistry) (Formalin-fixed, paraffin-embedded human tonsil stained with Collagen IV Recombinant Rabbit Monoclonal Antibody (COL4/4241R).)
References
Smrkolj S et al. Eur J Gynaecol Oncol. 2010; 31(4):380- 5.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
161kDa
NCBI Official Full Name
collagen alpha-1(IV) chain preproprotein
UniProt Protein Name
Collagen alpha-1(IV) chain
UniProt Gene Name
COL4A1
UniProt Entry Name
CO4A1_HUMAN

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Product Notes

The COL4A col4a1 (Catalog #AAA215420) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Collagen IV reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Collagen IV can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the COL4A col4a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Collagen IV, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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