Mouse anti-Human DR3 Monoclonal Antibody | anti-DR3 antibody
DR3 antibody
Gene Names
TNFRSF25; DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12
Reactivity
Human
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
DR3 antibody was purified by affinity chromatography.
Synonyms
DR3, Antibody; DR3 antibody; Monoclonal DR3; Anti-DR3; Apo-3; Tyrosine-rich acidic matrix protein; TRAIL Receptor family; DR 3; DR-3; DR3; TRAMP; anti-DR3 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
JD3
Specificity
Human
Purity/Purification
DR3 antibody was purified by affinity chromatography.
Form/Format
Affinity purified supplied as liquid in PBS, pH 7.2, with 0.09% NaN3
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
417
Applicable Applications for anti-DR3 antibody
IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry)
Biological Significance
The JD3 monoclonal antibody reacts with human DR3, also known as Apo-3, WSL-1, TRAMP, LARD, DDR3, and TR3. DR3, a novel death receptor is expressed at low level by monocytes and granulocytes. Interaction of DR3 with its ligand activates NF-kappaB pathway and induces apoptosis. Initially, DR3 was thought to be a receptor for TWEAK, but further studies have shown that TWEAK could induce apoptosis via receptors distinct from DR3. JD3 has been reported for use in flow cytometric analysis.
Preparation and Storage
Store at 4°C. Do not freeze. Protect from light.
Related Product Information for anti-DR3 antibody
Mouse monoclonal DR3 antibody
Product Categories/Family for anti-DR3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
29,111 Da
NCBI Official Full Name
DR3
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 25
NCBI Official Symbol
TNFRSF25
NCBI Official Synonym Symbols
DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12
NCBI Protein Information
tumor necrosis factor receptor superfamily member 25
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 25
UniProt Gene Name
TNFRSF25
UniProt Synonym Gene Names
APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; LARD
UniProt Entry Name
TNR25_HUMAN
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Product Notes
The DR3 tnfrsf25 (Catalog #AAA107527) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The DR3 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DR3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the DR3 tnfrsf25 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DR3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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