Application Data
(FFPE human glioblastomawith IDH1-R132H mutationstained with IDH1-R132HRecombinant Rabbit Monoclonal Antibody (IDH1/6806R).)
Rabbit anti-Human IDH1-R132H Monoclonal Antibody | anti-IDH1 antibody
IDH1-R132H (Isocitrate Dehydrogenase) Recombinant Rabbit Monoclonal Antibody [Clone IDH1/6806R]
Gene Names
IDH1; IDH; IDP; IDCD; IDPC; PICD; HEL-216; HEL-S-26
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
IDH1-R132H, Antibody; IDH1-R132H (Isocitrate Dehydrogenase) Recombinant Rabbit Monoclonal Antibody [Clone IDH1/6806R]; IDH1-R132H (Isocitrate Dehydrogenase); Cytosolic NADP-isocitrate dehydrogenase; Epididymis luminal protein 216; Epididymis secretory protein Li 26; HEL-216; HEL-S-26; ICDH; IDCD; IDH1; IDP; IDPC; Isocitrate dehydrogenase 1 (NADP+) soluble; NADP dependent isocitrate dehydrogenase peroxisomal; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; PICD; anti-IDH1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit/IgG, kappa
Clone Number
IDH1/6806R
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-IDH1 antibody
IHC (Immunohistochemistry)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant fragment of human IDH1 protein (around aa 281-414) (exact sequence is proprietary)
Cellular Localization
Cytoplasm, Nucleus
Positive Control
HepG2, HeLa, HT29 or MCF7cells. Humanbreast, colon or prostate carcinoma.
Hu-chromosome Location
2q33.3
Unigene
593422
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Application Data
(FFPE human glioblastomawith IDH1-R132H mutationstained with IDH1-R132HRecombinant Rabbit Monoclonal Antibody (IDH1/6806R).)
Application Data
(FFPE human glioblastomawith IDH1-R132H mutationstained with IDH1-R132HRecombinant Rabbit Monoclonal Antibody (IDH1/6806R).)
Related Product Information for anti-IDH1 antibody
IDH1 R132H antibody binds to IDH1-mutated protein, but does not bind the wild-type IDH1 protein. IDH1 R132H point mutations are frequently seen in World Health Organization grade II and III gliomas and are believed to constitute an early step in tumorigenesis. IDH1 R132H can be used as a test marker to help differentiate infiltrating gliomas from gliosis, and as a prognostic marker for gliomas and secondary glioblastoma multiforme. IDH1 R132H antibody shows strong cytoplasmic staining and weaker nuclear staining in tumor cells with the R132H-mutated peptide. Diffuse staining of the fibrillary tumor matrix is also seen.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
46,659 Da
NCBI Official Full Name
isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_b
NCBI Official Synonym Full Names
isocitrate dehydrogenase 1 (NADP+), soluble
NCBI Official Symbol
IDH1
NCBI Official Synonym Symbols
IDH; IDP; IDCD; IDPC; PICD; HEL-216; HEL-S-26
NCBI Protein Information
isocitrate dehydrogenase [NADP] cytoplasmic; isocitrate dehydrogenase [NADP] cytoplasmic; NADP(+)-specific ICDH; oxalosuccinate decarboxylase; epididymis luminal protein 216; epididymis secretory protein Li 26; NADP-dependent isocitrate dehydrogenase, cyt
UniProt Protein Name
Isocitrate dehydrogenase [NADP] cytoplasmic
UniProt Gene Name
IDH1
UniProt Synonym Gene Names
PICD; IDH
UniProt Entry Name
IDHC_HUMAN
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Product Notes
The IDH1 idh1 (Catalog #AAA215723) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IDH1-R132H (Isocitrate Dehydrogenase) Recombinant Rabbit Monoclonal Antibody [Clone IDH1/6806R] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IDH1-R132H can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the IDH1 idh1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IDH1-R132H, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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