Application Data
(Formalin fixed, paraffin embedded normal colon and colon adenocarcinoma stained with Mouse anti Human IRF5 following heat mediated antigen retrieval using 0.1M citrate buffer (pH6.0))
Mouse IRF5 Monoclonal Antibody | anti-IRF5 antibody
MOUSE ANTI HUMAN IRF5
Gene Names
IRF5; SLEB10
Applications
Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA
Synonyms
IRF5, Antibody; MOUSE ANTI HUMAN IRF5; anti-IRF5 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10T1
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0mg/ml (varies by lot)
Sequence Length
498
Applicable Applications for anti-IRF5 antibody
WB (Western Blot), IHC (Immunohistochemistry), IP (Immunoprecipitation), ELISA
Perservative Stabilisers
0.1% Sodium Azide (NaN3)
Preparation
Preparation
Histology Positive Control Tissue
Human Colon
Buffer Solution
Buffer Solution
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Application Data
(Formalin fixed, paraffin embedded normal colon and colon adenocarcinoma stained with Mouse anti Human IRF5 following heat mediated antigen retrieval using 0.1M citrate buffer (pH6.0))
Application Data
(Formalin fixed, paraffin embedded normal colon and colon adenocarcinoma stained with Mouse anti Human IRF5 following heat mediated antigen retrieval using 0.1M citrate buffer (pH6.0))
Application Data
(Western blot analysis of IRF5 expression in a range of cell lines using Mouse anti Human IRF5)
Application Data
(Western blot analysis of IRF5 expression in a range of cell lines using Mouse anti Human IRF5)
Related Product Information for anti-IRF5 antibody
Mouse anti Human IRF5, clone 10T1 recognises human interferon regulatory factor 5 (IRF5), a 58kDa member of the IRF family which acts as a key regulator of interferon gene transcription, and is expressed in B cells and dendritic cells, and is inducible by type I interferon (IFN) in most lymphoid cells. The role of IRF3 and IRF7 as transcriptional mediators of virus- and IFN-induced signaling pathways is well documented. Studies have shown that IRF5 can also regulate IFN gene transcription, but appears to be more restricted in its cellular expression and range of viral stimuli, and has the ability to induce a wide range of chemokines involved in T-lymphocyte recruitment, including RANTES, MCP-1 and IP-10 (Barnes et al. 2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17,020 Da
NCBI Official Full Name
interferon regulatory factor 5 isoform b
NCBI Official Synonym Full Names
interferon regulatory factor 5
NCBI Official Symbol
IRF5
NCBI Official Synonym Symbols
SLEB10
NCBI Protein Information
interferon regulatory factor 5
UniProt Protein Name
Interferon regulatory factor 5
UniProt Gene Name
IRF5
UniProt Synonym Gene Names
IRF-5
UniProt Entry Name
IRF5_HUMAN
Similar Products
Product Notes
The IRF5 irf5 (Catalog #AAA49539) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IRF5 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IP (Immunoprecipitation), ELISA. Researchers should empirically determine the suitability of the IRF5 irf5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IRF5, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.