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product-image-AAA314255_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of RAB8A in paraffin-embedded Human colon cancer tissue using RAB8A Rabbit mAb at dilution 1/1)

Rab8A Monoclonal Antibody | anti-Rab8A antibody

Rab8A Rabbit mAb

Gene Names
RAB8A; MEL; RAB8
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
Rab8A, Antibody; Rab8A Rabbit mAb; RAB8A, member RAS oncogene family; MEL; RAB8; anti-Rab8A antibody
Ordering
Host
Recombinant Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
S06-8A7
Purity/Purification
Affinity Purified
Form/Format
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration
0.3mg/ml (varies by lot)
Applicable Applications for anti-Rab8A antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide of human RAB8A
Conjugation
Unconjugated
Modification
Unmodification
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.

IHC (Immunohistochemisry)

(Immunohistochemistry of RAB8A in paraffin-embedded Human colon cancer tissue using RAB8A Rabbit mAb at dilution 1/1)

product-image-AAA314255_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of RAB8A in paraffin-embedded Human colon cancer tissue using RAB8A Rabbit mAb at dilution 1/1)

IF (Immunofluorescence)

(Immunofluorescence of Rab8A(green) in Hela cells using Rab8A Rabbit mAb at dilution 1/200, and DAPI(blue))

product-image-AAA314255_IF13.jpg IF (Immunofluorescence) (Immunofluorescence of Rab8A(green) in Hela cells using Rab8A Rabbit mAb at dilution 1/200, and DAPI(blue))

WB (Western Blot)

(Western blot detection of RAB8A in K562,C6,3T3,Hela cell lysates using RAB8A Rabbit mAb(1:1000 diluted).Predicted band size:24kDa.Observed band size:24kDa.)

product-image-AAA314255_WB15.jpg WB (Western Blot) (Western blot detection of RAB8A in K562,C6,3T3,Hela cell lysates using RAB8A Rabbit mAb(1:1000 diluted).Predicted band size:24kDa.Observed band size:24kDa.)
Related Product Information for anti-Rab8A antibody
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (PubMed:20890297).
Product Categories/Family for anti-Rab8A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
207
NCBI Official Full Name
Ras-related protein Rab-8A
NCBI Official Synonym Full Names
RAB8A, member RAS oncogene family
NCBI Official Symbol
RAB8A
NCBI Official Synonym Symbols
MEL; RAB8
NCBI Protein Information
ras-related protein Rab-8A; oncogene c-mel; ras-associated protein RAB8; mel transforming oncogene (RAB8 homolog); mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog
UniProt Protein Name
Ras-related protein Rab-8A
UniProt Gene Name
RAB8A
UniProt Synonym Gene Names
MEL; RAB8
UniProt Entry Name
RAB8A_HUMAN

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Product Notes

The Rab8A rab8a (Catalog #AAA314255) is an Antibody produced from Recombinant Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rab8A Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Rab8A can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Rab8A rab8a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rab8A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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