Mouse SIRT1 Monoclonal Antibody | anti-SIRT1 antibody

SIRT1 Monoclonal Antibody

Cat. Num. AAA320225

• Gene Names: SIRT1; SIR2L1
• Reactivity: Human, Monkey
• Applications: ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Affinity purification
• Synonyms: SIRT1, Antibody; SIRT1 Monoclonal Antibody; NAD-dependent deacetylase sirtuin-1; SIRT1; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2; anti-SIRT1 antibody

• Host: Mouse
• Reactivity: Human, Monkey
• Clonality: Monoclonal
• Specificity: SIRT1 Monoclonal Antibody detects endogenous levels of SIRT1 protein.
• Purity/Purification: Affinity purification
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applicable Applications for anti-SIRT1 antibody: ELISA, FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Purified recombinant fragment of human SIRT1 expressed in E coli.
• Modification: Unmodified/Total
• Preparation and Storage: Store at -20 degree C/1 year

FCM/FACS (Flow Cytometry)

(Flow cytometric analysis of K562 cells using SIRT1 Monoclonal Antibody (green) and negative control (purple).)

IF (Immunofluorescence)

(Immunofluorescence analysis of NTERA-2 cells using SIRT1 Monoclonal Antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)

IHC (Immunohiostchemistry)

(Immunohistochemistry analysis of paraffin-embedded lung cancer tissues (left) and kidney cancer tissues (right) with DAB staining using SIRT1 Monoclonal Antibody.)

WB (Western Blot)

(Western Blot analysis using SIRT1 Monoclonal Antibody against MCF-7 (1). Jurkat (2). HeLa (3). HEK293 (4) and A549 (5) cell lysate.)

Related Product Information for anti-SIRT1 antibody

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Product Categories/Family for anti-SIRT1 antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 215982798
• NCBI GeneID: 23411
• NCBI Accession #: NP_001135970.1
• NCBI GenBank Nucleotide #: NM_001142498.1
• UniProt Accession #: Q96EB6; Q2XNF6; Q5JVQ0; Q9GZR9; Q9Y6F0
• Molecular Weight: 81,681 Da
• NCBI Official Full Name: NAD-dependent protein deacetylase sirtuin-1 isoform b
• NCBI Official Synonym Full Names: sirtuin 1
• NCBI Official Symbol: SIRT1
• NCBI Official Synonym Symbols: SIR2L1
• NCBI Protein Information: NAD-dependent protein deacetylase sirtuin-1; hSIR2; hSIRT1; SIR2alpha; sir2-like 1; sirtuin type 1; SIR2-like protein 1; regulatory protein SIR2 homolog 1; NAD-dependent deacetylase sirtuin-1
• UniProt Protein Name: NAD-dependent protein deacetylase sirtuin-1
• UniProt Gene Name: SIRT1
• UniProt Synonym Gene Names: SIR2L1; hSIRT1; hSIR2; 75SirT1
• UniProt Entry Name: SIR1_HUMAN