Rabbit ARID1A Polyclonal Antibody | anti-ARID1A antibody

ARID1A Antibody

Cat. Num. AAA40742

• Gene Names: ARID1A; ELD; B120; OSA1; P270; hELD; BM029; MRD14; hOSA1; BAF250; C1orf4; BAF250a; SMARCF1
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
• Purity: ARID1A antibody is affinity chromatography purified via peptide column.
• Synonyms: ARID1A, Antibody; ARID1A Antibody; AT rich interactive domain 1A (SWI-like); RP1-50O24.1; B120; BAF250; BAF250a; BM029; C1orf4; ELD; hELD; MRD14; OSA1; hOSA1; P270; SMARCF1; anti-ARID1A antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: ARID1A antibody is human, mouse and rat reactive. Multiple isoforms of ARID1A protein are known to exist.
• Purity/Purification: ARID1A antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 2285

• Applicable Applications for anti-ARID1A antibody: IHC (Immunohistochemistry), IF (Immunofluorescence), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: ARID1A antibody was raised against an 18 amino acid peptide near the amino terminus of human ARID1A.
• Buffer: ARID1A antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: ARID1A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

IF (Immunofluorescence)

(Immunofluorescence of ARID1A in mouse brain tissue with ARID1A antibody at 20 μg/ml.)

IF (Immunofluorescence)

(Immunofluorescence of ARID1A in mouse brain tissue with ARID1A antibody at 20 μg/ml.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of ARID1A in mouse brain tissue with ARID1A antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of ARID1A in SK-N-SH cell lysate with ARID1A antibody at (A) 1 and (B) 2 μg/ml.)

Related Product Information for anti-ARID1A antibody

The ARID1A protein is a member of the SWI/SNF family, whose members are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. ARID1A is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin (1). It possesses a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. The C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that ARID1A confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions (2).

NCBI and Uniprot Product Information

• NCBI GI #: 21264565
• NCBI GeneID: 8289
• NCBI Accession #: NP_006006
• NCBI GenBank Nucleotide #: NM_006015.4
• UniProt Accession #: O14497; Q53FK9; Q5T0W1; Q5T0W2; Q5T0W3; Q8NFD6; Q96T89; Q9BY33; Q9HBJ5; Q9UPZ1; D3DPL1
• Molecular Weight: Predicted: 133; 227; 251 kDa; ; Observed: 130; 260 kDa
• NCBI Official Full Name: AT-rich interactive domain-containing protein 1A isoform a
• NCBI Official Synonym Full Names: AT rich interactive domain 1A (SWI-like)
• NCBI Official Symbol: ARID1A
• NCBI Official Synonym Symbols: ELD; B120; OSA1; P270; hELD; BM029; MRD14; hOSA1; BAF250; C1orf4; BAF250a; SMARCF1
• NCBI Protein Information: AT-rich interactive domain-containing protein 1A; osa homolog 1; SWI-like protein; brain protein 120; OSA1 nuclear protein; BRG1-associated factor 250a; SWI/SNF complex protein p270; chromatin remodeling factor p250; ARID domain-containing protein 1A; SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1
• UniProt Protein Name: AT-rich interactive domain-containing protein 1A
• UniProt Gene Name: ARID1A
• UniProt Synonym Gene Names: BAF250; BAF250A; C1orf4; OSA1; SMARCF1; ARID domain-containing protein 1A; BAF250; BAF250A; hOSA1
• UniProt Entry Name: ARI1A_HUMAN