WB (Western Blot)
(Western blot analysis of 30 ug of whole cell lysate (A: MOLT4) using a 10 % SDS PAGE gel and DNase I antibody at a dilution of 1:1000)
Rabbit DNase I Polyclonal Antibody | anti-DNase I antibody
DNase I antibody
Applications
Western Blot, Immunocytochemistry, Immunofluorescence
Purity
DNase I antibody was purified by antigen-affinity chromatography
Synonyms
DNase I, Antibody; DNase I antibody; Polyclonal DNase I; Anti-DNase I; Dornase alfa; FLJ44902; deoxyribonuclease I; DNL1; FLJ38093; deoxyribonuclease-1; DNase I lysosomal; DRNI; human urine deoxyribonuclease I; DKFZp686H0155; DNASE1; anti-DNase I antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
DNase I antibody was purified by antigen-affinity chromatography
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
1 mg/ml (varies by lot)
Sequence Length
282
Applicable Applications for anti-DNase I antibody
WB (Western Blot), ICC (Immunocytochemistry), IF (Immunofluorescence)
Biological Significance
This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus, an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity.
Cross-Reactivity
Human
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
WB (Western Blot)
(Western blot analysis of 30 ug of whole cell lysate (A: MOLT4) using a 10 % SDS PAGE gel and DNase I antibody at a dilution of 1:1000)
WB (Western Blot)
(Western blot analysis of 30 ug of whole cell lysate (A: MOLT4) using a 10 % SDS PAGE gel and DNase I antibody at a dilution of 1:1000)
IF (Immunofluorescence)
(Immunofluorescence analysis of methanol-fixed HeLa, using DNase I antibody at 1:200 dilution.)
IF (Immunofluorescence)
(Immunofluorescence analysis of methanol-fixed HeLa, using DNase I antibody at 1:200 dilution.)
Related Product Information for anti-DNase I antibody
Affinity purified Rabbit polyclonal DNase I antibody
Product Categories/Family for anti-DNase I antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
31 kDa
NCBI Official Full Name
DNase I
UniProt Protein Name
Deoxyribonuclease-1
UniProt Gene Name
DNASE1
UniProt Synonym Gene Names
DNL1; DRNI; DNase I
UniProt Entry Name
DNAS1_HUMAN
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Product Notes
The DNase I dnase1 (Catalog #AAA107798) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DNase I can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ICC (Immunocytochemistry), IF (Immunofluorescence). Researchers should empirically determine the suitability of the DNase I dnase1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNase I, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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