IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using Nhe-1 antibody at 2.5 ug/mL.)
Rabbit Nhe-1 Polyclonal Antibody | anti-Nhe-1 antibody
Nhe-1 Antibody
Gene Names
SLC9A1; APNH; NHE1; LIKNS; NHE-1; PPP1R143
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Nhe-1, Antibody; Nhe-1 Antibody; Sodium-hydrogen exchanger 1, solute carrier family 9 member 1, SLC9A1, Na+, H+ antiporter; anti-Nhe-1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
815
Applicable Applications for anti-Nhe-1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 20 amino acid peptide near the carboxy terminus of the human Nhe-1.
Target Name
Nhe-1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using Nhe-1 antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using Nhe-1 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of Nhe-1 in rat kidney tissue lysate with in with Nhe-1 antibody at (A) 1 and (B) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of Nhe-1 in rat kidney tissue lysate with in with Nhe-1 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-Nhe-1 antibody
The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thought that Nhe-1 play a role in hypertension. At least two isoforms of Nhe-1 are known to exist.
Product Categories/Family for anti-Nhe-1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
61,013 Da
NCBI Official Full Name
sodium/hydrogen exchanger 1
NCBI Official Synonym Full Names
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
NCBI Official Symbol
SLC9A1
NCBI Official Synonym Symbols
APNH; NHE1; LIKNS; NHE-1; PPP1R143
NCBI Protein Information
sodium/hydrogen exchanger 1
UniProt Protein Name
Sodium/hydrogen exchanger 1
UniProt Gene Name
SLC9A1
UniProt Synonym Gene Names
APNH1; NHE1; NHE-1
UniProt Entry Name
SL9A1_HUMAN
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Product Notes
The Nhe-1 slc9a1 (Catalog #AAA308168) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Nhe-1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Nhe-1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Nhe-1 slc9a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nhe-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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