IHC (Immunohiostchemistry)
(STIM1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STIM1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit STIM1 Polyclonal Antibody | anti-STIM1 antibody
STIM1 Antibody (C-term)
Gene Names
STIM1; GOK; TAM; TAM1; IMD10; STRMK; D11S4896E
Reactivity
Human (Predicted Reactivity: Mouse)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
STIM1, Antibody; STIM1 Antibody (C-term); Stromal interaction molecule 1; STIM1; GOK; anti-STIM1 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This STIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 509-538 amino acids from the C-terminal region of human STIM1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
509-538
Sequence Length
540
Applicable Applications for anti-STIM1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(STIM1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STIM1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(STIM1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STIM1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(STIM1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the STIM1 antibody detected the STIM1 protein (arrow).)
WB (Western Blot)
(STIM1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the STIM1 antibody detected the STIM1 protein (arrow).)
Related Product Information for anti-STIM1 antibody
This gene encodes a type 1 transmembrane protein that
mediates Ca2+ influx after depletion of intracellular Ca2+ stores
by gating of store-operated Ca2+ influx channels (SOCs). It is one
of several genes located in the imprinted gene domain of 11p15.5,
an important tumor-suppressor gene region. Alterations in this
region have been associated with the Beckwith-Wiedemann syndrome,
Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung,
ovarian, and breast cancer. This gene may play a role in
malignancies and disease that involve this region, as well as early
hematopoiesis, by mediating attachment to stromal cells. This gene
is oriented in a head-to-tail configuration with the ribonucleotide
reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6
kb from the 5' end of the RRM1 gene.
mediates Ca2+ influx after depletion of intracellular Ca2+ stores
by gating of store-operated Ca2+ influx channels (SOCs). It is one
of several genes located in the imprinted gene domain of 11p15.5,
an important tumor-suppressor gene region. Alterations in this
region have been associated with the Beckwith-Wiedemann syndrome,
Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung,
ovarian, and breast cancer. This gene may play a role in
malignancies and disease that involve this region, as well as early
hematopoiesis, by mediating attachment to stromal cells. This gene
is oriented in a head-to-tail configuration with the ribonucleotide
reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6
kb from the 5' end of the RRM1 gene.
Product Categories/Family for anti-STIM1 antibody
References
Byun, M., et al. J. Exp. Med. 207(11):2307-2312(2010)
Park, C.Y., et al. Science 330(6000):101-105(2010)
Walsh, C.M., et al. Biochem. J. 430(3):453-460(2010)
Hawkins, B.J., et al. J. Cell Biol. 190(3):391-405(2010)
Woodward, O.M., et al. PLoS ONE 5 (8), E12305 (2010) :
Park, C.Y., et al. Science 330(6000):101-105(2010)
Walsh, C.M., et al. Biochem. J. 430(3):453-460(2010)
Hawkins, B.J., et al. J. Cell Biol. 190(3):391-405(2010)
Woodward, O.M., et al. PLoS ONE 5 (8), E12305 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
77423
NCBI Official Full Name
stromal interaction molecule 1 isoform 3
NCBI Official Synonym Full Names
stromal interaction molecule 1
NCBI Official Symbol
STIM1
NCBI Official Synonym Symbols
GOK; TAM; TAM1; IMD10; STRMK; D11S4896E
NCBI Protein Information
stromal interaction molecule 1
UniProt Protein Name
Stromal interaction molecule 1
UniProt Gene Name
STIM1
UniProt Synonym Gene Names
GOK
UniProt Entry Name
STIM1_HUMAN
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Product Notes
The STIM1 stim1 (Catalog #AAA288560) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 509-538. The STIM1 Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's STIM1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the STIM1 stim1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STIM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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