IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using TRIM24 antibody.)
Rabbit anti-Human, Mouse TRIM24 Polyclonal Antibody | anti-TRIM24 antibody
TRIM24 Antibody
Gene Names
TRIM24; PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
TRIM24, Antibody; TRIM24 Antibody; TIF1; TIF1A; TRIM24; Transcription intermediary factor 1-alpha; Tripartite motif protein 24; anti-TRIM24 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total TRIM24 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
1016
Applicable Applications for anti-TRIM24 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from C-terminal of human TRIM24.
Target Name
TRIM24
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using TRIM24 antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using TRIM24 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from COLO cells, using TRIM24 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from COLO cells, using TRIM24 antibody.)
Related Product Information for anti-TRIM24 antibody
Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes By similarity.Thenot S., J. Biol. Chem. 272:12062-12068(1997).Venturini L., Oncogene 18:1209-1217(1999).Hellal-Levy C., Mol. Endocrinol. 14:1210-1221(2000).
Product Categories/Family for anti-TRIM24 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
113,018 Da
NCBI Official Full Name
transcription intermediary factor 1-alpha isoform b
NCBI Official Synonym Full Names
tripartite motif containing 24
NCBI Official Symbol
TRIM24
NCBI Official Synonym Symbols
PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA
NCBI Protein Information
transcription intermediary factor 1-alpha
UniProt Protein Name
Transcription intermediary factor 1-alpha
UniProt Gene Name
TRIM24
UniProt Synonym Gene Names
RNF82; TIF1; TIF1A; TIF1-alpha
UniProt Entry Name
TIF1A_HUMAN
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Product Notes
The TRIM24 trim24 (Catalog #AAA306735) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRIM24 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TRIM24 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TRIM24 trim24 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRIM24, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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