IHC (Immunohiostchemistry)
(Immunohistochemistry of XEDAR in human skin tissue with XEDAR antibody at 10 ug/mL.)
Rabbit anti-Human XEDAR Polyclonal Antibody | anti-XEDAR antibody
XEDAR Antibody
Gene Names
EDA2R; XEDAR; EDAA2R; EDA-A2R; TNFRSF27
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
XEDAR, Antibody; XEDAR Antibody; X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, TNFRSF27; anti-XEDAR antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
297
Applicable Applications for anti-XEDAR antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Recombinant protein
Immunogen Description
Raised against recombinant human XEDAR.
Target Name
XEDAR
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of XEDAR in human skin tissue with XEDAR antibody at 10 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of XEDAR in human skin tissue with XEDAR antibody at 10 ug/mL.)
WB (Western Blot)
(Western blot analysis of XEDAR in 293 cell lysate with XEDAR antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of XEDAR in 293 cell lysate with XEDAR antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.)
Related Product Information for anti-XEDAR antibody
X-linked ectodysplasin-A2 receptor (XEDAR) is a recently isolated member of the tumor necrosis factor receptor family that is highly expressed during embryonic development and binds to ectodysplatin-A2 (EDA-A2). Two predominantly expressed isoforms, XEDAR-s and XEDAR-L, differ by only a 21-amino region at the juxtamembrane region of the cytoplasmic domain. Neither isoform possesses a death domain and both have been shown to act mainly through TRAF3 and TRAF6 to activate the NF-kB and JNK pathways. Cells transfected with XEDAR and treated with EDA-A2 cause the assembly of a secondary complex containing FADD, caspase-8 and caspase-10, leading to the activation caspase-8 and caspase-3, and finally apoptosis. The EDA-A2-induced apoptosis is dependent on caspase-9 activation, as various pharmacological and genetic inhibitors of caspase-8 blocked apoptosis following EDA-A2 treatment.
Product Categories/Family for anti-XEDAR antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
32,959 Da
NCBI Official Full Name
XEDAR
NCBI Official Synonym Full Names
ectodysplasin A2 receptor
NCBI Official Symbol
EDA2R
NCBI Official Synonym Symbols
XEDAR; EDAA2R; EDA-A2R; TNFRSF27
NCBI Protein Information
tumor necrosis factor receptor superfamily member 27
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 27
UniProt Gene Name
EDA2R
UniProt Synonym Gene Names
TNFRSF27; XEDAR; EDA-A2 receptor
UniProt Entry Name
TNR27_HUMAN
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Product Notes
The XEDAR eda2r (Catalog #AAA300961) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XEDAR Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's XEDAR can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the XEDAR eda2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "XEDAR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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