Filters
▼Clonality
▼Type
▼Reactivity
▼Gene Name
▼Isotype
▼Host
▼Application
▼Clone
▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 200-250 of 2567 product results
Bioactivity
(Interleukin 9, also known as IL-9, is a pleiotropic cytokine belonging to the group of interleukins. IL-9 secreted by CD4 helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins namely STAT1, STAT3 and STAT5 and thus connects this cytokine to various biological processes. Besides, Interleukin 9 Receptor (IL9R) has been identified as an interactor of IL-9, thus a binding ELISA assay was conducted to detect the interaction of recombinant human IL-9 and recombinant human IL9R. Briefly, IL-9 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to IL9R-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-IL-9 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of IL-9 and IL9R was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of IL-9 with IL9R)
Interleukin 9, Active Protein (Cat# AAA150065)
Full Name
Active Interleukin 9 (IL9)
Gene Names
IL9; P40; HP40; IL-9
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Application Data
(Tissue Factor Pathway Inhibitor 2 (TFPI2) takes part in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. TFPI2 doesn’t have any influence on thrombin. TFPI2 also can inhibit MMP activity, which can hydrolyze gelatin under certain conditions. Thus, the activity of TFPI2 can be measured by inhibit MMP-2 hydrolyze gelatin. Gelatin zymography is mainly used for the detection of the gelatinases, 2g/mL was denatured by SDS loading buffer, electrophoresed through sodium dodecylsulphate–polyacrylamide gel (SDS–PAGE; 8% gels) containing gelatin (1mg/mL) with nonreducing conditions. After renaturation, incubate with various concentrations of recombinant mouse TFPI2, then staining with coomassie brilliant blue G250, active MMP-2 would hydrolyze gelatin nearby, which was indicated by the white binds on the gel; if the activity of MMP-2 inhibit by TFPI2, there was none white binds on the gel.The result was shown in figure 1.As the figure 1 shown, MMP-2 can be inhibited by recombinant mouse TFPI2 at least 2.5g/mL.)
Tissue Factor Pathway Inhibitor 2, Active Protein (Cat# AAA150120)
Full Name
Active Tissue Factor Pathway Inhibitor 2 (TFPI2)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Bioactivity
(Figure. The binding activity of SIRT3 with IDH2.)
Sirtuin 3, Active Protein (Cat# AAA150138)
Full Name
Active Sirtuin 3 (SIRT3)
Gene Names
SIRT3; SIR2L3
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Sequence
Interleukin 12B (IL12B), Active Protein (Cat# AAA150970)
Full Name
Active Interleukin 12B (IL12B)
Gene Names
IL12B; CLMF; NKSF; CLMF2; NKSF2; IL-12B
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Myeloid cell surface antigen CD33 (CD33), Active Protein (Cat# AAA114015)
Full Name
Recombinant Human Myeloid cell surface antigen CD33 (CD33), partial
Gene Names
CD33; p67; SIGLEC3; SIGLEC-3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
SDS-PAGE
C-C motif chemokine 3 protein (Ccl3), Active Protein (Cat# AAA114236)
Full Name
Recombinant Rat C-C motif chemokine 3 protein (Ccl3) (Active)
Gene Names
Ccl3; Scya3; MIP-1a
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
SDS-PAGE
Fibroblast growth factor 23 protein (FGF23), Active Protein (Cat# AAA114242)
Full Name
Recombinant Human Fibroblast growth factor 23 protein (FGF23) (Active)
Gene Names
FGF23; ADHR; FGFN; HYPF; HPDR2; PHPTC
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Application Data
FGF1, Active Protein (Cat# AAA214210)
Full Name
Recombinant Human FGF1
Gene Names
FGF1; AFGF; ECGF; FGFA; ECGFA; ECGFB; FGF-1; HBGF1; HBGF-1; GLIO703; ECGF-beta; FGF-alpha
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
BAFF-R (TNFRSF13C), Active Protein (Cat# AAA214211)
Full Name
Recombinant Human BAFF-R (TNFRSF13C)
Gene Names
TNFRSF13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
Beta-Defensin 3 (DEFB103A), Active Protein (Cat# AAA214214)
Full Name
Recombinant Human Beta-Defensin 3 (DEFB103A)
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
EGF, Active Protein (Cat# AAA214216)
Full Name
Recombinant Human EGF
Gene Names
EGF; URG; HOMG4
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
Eotaxin (CCL11), Active Protein (Cat# AAA214217)
Full Name
Recombinant Human Eotaxin (CCL11)
Gene Names
CCL11; SCYA11
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
CCL21, Active Protein (Cat# AAA214218)
Full Name
Recombinant Human CCL21
Gene Names
CCL21; ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
GH1, Active Protein (Cat# AAA214221)
Full Name
Recombinant Human GH1
Gene Names
GH1; GH; GHN; GH-N; GHB5; IGHD2; hGH-N; IGHD1A; IGHD1B
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
CXCL1, Active Protein (Cat# AAA214223)
Full Name
Recombinant Human CXCL1
Gene Names
CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
HCC-2 (CCL15), Active Protein (Cat# AAA214226)
Full Name
Recombinant Human HCC-2 (CCL15)
Gene Names
CCL15; LKN1; NCC3; SY15; HCC-2; LKN-1; MIP-5; NCC-3; SCYL3; MIP-1D; MRP-2B; SCYA15; HMRP-2B; MIP-1 delta
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
FGF4, Active Protein (Cat# AAA214307)
Full Name
Recombinant Human FGF4
Gene Names
FGF4; HST; KFGF; FGF-4; HST-1; HSTF1; K-FGF; HBGF-4; HSTF-1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
PlGF, Active Protein (Cat# AAA214308)
Full Name
Recombinant Human PlGF
Gene Names
PGF; PGFL; PIGF; PLGF; PlGF-2; D12S1900; SHGC-10760
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
FGF1, Active Protein (Cat# AAA214309)
Full Name
Recombinant Mouse FGF1
Gene Names
Fgf1; Fam; Fgfa; Dffrx; Fgf-1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
IL13, Active Protein (Cat# AAA214322)
Full Name
Recombinant Mouse IL13
Gene Names
Il13; Il-13
Purity
>95% as determined by SDS-PAGE
Pricing
Beta-Defensin 2 (DEFB2), Active Protein (Cat# AAA214326)
Full Name
Recombinant Mouse Beta-Defensin 2 (DEFB2)
Gene Names
Defb2; BD-2
Reactivity
Mouse (M. musculus)
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
CXCL1, Active Protein (Cat# AAA214328)
Full Name
Recombinant Mouse CXCL1
Gene Names
Cxcl1; KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
VEGF, Active Protein (Cat# AAA214333)
Full Name
Recombinant Mouse VEGF (164aa)
Gene Names
Vegfa; Vpf; Vegf
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
TNF, Active Protein (Cat# AAA214338)
Full Name
Recombinant Rat TNF
Gene Names
Tnf; Tnfa; RATTNF; TNF-alpha
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
IL1B, Active Protein (Cat# AAA214339)
Full Name
Recombinant Rat IL1B
Gene Names
Il1b; IL-1F2
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
CXCL1, Active Protein (Cat# AAA214340)
Full Name
Recombinant Rat CXCL1
Gene Names
Cxcl1; Gro1; CINC-1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
GRO gamma (CXCL3), Active Protein (Cat# AAA214342)
Full Name
Recombinant Rat GRO gamma (CXCL3)
Gene Names
Cxcl3; Cinc2; Cinc-2; Gm1960
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
IL2, Active Protein (Cat# AAA214344)
Full Name
Recombinant Rat IL2
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
IL15, Active Protein (Cat# AAA214232)
Full Name
Recombinant Human IL15
Gene Names
IL15; IL-15
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
IL3, Active Protein (Cat# AAA214236)
Full Name
Recombinant Human IL3
Gene Names
IL3; IL-3; MCGF; MULTI-CSF
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
CXCL11, Active Protein (Cat# AAA214238)
Full Name
Recombinant Human CXCL11
Gene Names
CXCL11; IP9; H174; IP-9; b-R1; I-TAC; SCYB11; SCYB9B
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
CCL2, Active Protein (Cat# AAA214242)
Full Name
Recombinant Human CCL2
Gene Names
CCL2; HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
RANTES (CCL5), Active Protein (Cat# AAA214251)
Full Name
Recombinant Human RANTES (CCL5)
Gene Names
CCL5; SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
Resistin (RETN), Active Protein (Cat# AAA214252)
Full Name
Recombinant Human Resistin (RETN)
Gene Names
RETN; ADSF; RSTN; XCP1; FIZZ3; RETN1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
TNF, Active Protein (Cat# AAA214253)
Full Name
Recombinant Human TNF
Gene Names
TNF; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
VEGF, Active Protein (Cat# AAA214255)
Full Name
Recombinant Human VEGF (165aa)
Gene Names
VEGFA; VPF; VEGF; MVCD1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
CNTF, Active Protein (Cat# AAA214258)
Full Name
Recombinant Human CNTF
Gene Names
CNTF; HCNTF
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
B-Cell Maturation (TNFRSF17), Active Protein (Cat# AAA214266)
Full Name
Recombinant Human B-Cell Maturation Protein (TNFRSF17)
Gene Names
TNFRSF17; BCM; BCMA; CD269; TNFRSF13A
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
TFF3, Active Protein (Cat# AAA214283)
Full Name
Recombinant Human TFF3
Gene Names
TFF3; ITF; P1B; TFI
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
Prolactin (PRL), Active Protein (Cat# AAA214290)
Full Name
Recombinant Human Prolactin (PRL)
Gene Names
PRL; GHA1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
HB-EGF (Heparin Binding EGF), Active Protein (Cat# AAA214291)
Full Name
Recombinant Human HB-EGF (Heparin Binding EGF)
Gene Names
HBEGF; DTR; DTS; DTSF; HEGFL
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
IL36G, Active Protein (Cat# AAA214293)
Full Name
Recombinant Human IL36G
Gene Names
IL36G; IL1E; IL1F9; IL1H1; IL-1F9; IL-1H1; IL1RP2; IL-1RP2
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
IFNA4, Active Protein (Cat# AAA214301)
Full Name
Recombinant Human IFNA4
Gene Names
IFNA4; INFA4; IFN-alpha4a
Purity
>95% as determined by SDS-PAGE
Pricing
Bioactivity
(Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the Transforming Growth Factor beta (TGF-beta ) superfamily. Human GDF-15 shares 66% and 68% amino acid sequence identity with the ra)
Growth Differentiation Factor 15 (GDF15), Active Protein (Cat# AAA153111)
Full Name
Active Growth Differentiation Factor 15 (GDF15)
Gene Names
GDF15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Fibroblast growth factor 21 (FGF21) is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family which possess broad mitogenic and cell survival activities, and are in)
Fibroblast Growth Factor 21 (FGF21), Active Protein (Cat# AAA153123)
Full Name
Active Fibroblast Growth Factor 21 (FGF21)
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Interleukin 37, also known as Interleukin 1 Zeta (IL1z), is an anti-inflammatory cytokine. Interleukines are cytokines that make an important part of immune signaling. It belongs to the interleukin-1 family. IL-37 plays a role in protecting the body again)
Interleukin 1 Zeta (IL1z), Active Protein (Cat# AAA153127)
Full Name
Active Interleukin 1 Zeta (IL1z)
Gene Names
IL37; FIL1; FIL1Z; IL-1H; IL-37; IL1F7; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1; FIL1(ZETA)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
Bioactivity
(PECAM-1 (platelet-endothelial cell adhesion molecule-1; also known as CD31) is a 130 kDa type I transmembrane glycoprotein adhesion molecule in the immunoglobulin superfamily. Expression is restricted to cells involved in circulation, especially endotheli)
Platelet/Endothelial Cell Adhesion Molecule (PECAM1), Active Protein (Cat# AAA153034)
Full Name
Active Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
Gene Names
PECAM1; CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Interleukin 1 beta (IL-1beta) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a member of the interleukin 1 family of cytokines. This cytokine is an important medi)
Interleukin 1 Beta (IL1b), Active Protein (Cat# AAA153040)
Full Name
Active Interleukin 1 Beta (IL1b)
Gene Names
IL1B; IL-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
Bioactivity
(PLA2G-VII which is also known as Lp-PLA2, is a plasma enzyme bound to lipoproteins: 80% bound to LDL, 15%-20% to HDL, and the remainder to VLDL. It is produced in major by mature macrophages and activated platelets. In contrast to other classical sPLA2s,)
Phospholipase A2 Group VII (LpPLA2), Active Protein (Cat# AAA153065)
Full Name
Active Phospholipase A2 Group VII (LpPLA2)
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Neurosecretory protein VGF is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. Human VGF precursor is 615 amino acids (aa) in length. It contains an 22 aa signal sequence plus a 593 aa mature re)
VGF Nerve Growth Factor Inducible (VGF), Active Protein (Cat# AAA153074)
Full Name
Active VGF Nerve Growth Factor Inducible (VGF)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.