Mouse STIM1 Monoclonal Antibody | anti-STIM1 antibody
Anti-STIM1 Purified
Gene Names
STIM1; GOK; TAM; TAM1; IMD10; STRMK; D11S4896E
Reactivity
Rat, Human, Mouse
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Immunoprecipitation
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
STIM1, Antibody; Anti-STIM1 Purified; stromal interaction molecule 1; GOK; TAM1; STRMK; anti-STIM1 antibody
Host
Mouse
Reactivity
Rat, Human, Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
CDN3H4
Specificity
The mouse monoclonal antibody CDN3H4 reacts with a cytoplasmic epitope of human and rodent STIM1, a 84 kDa essential and conserved regulator of store-operated Ca2+ channel function.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Applicable Applications for anti-STIM1 antibody
ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot), IP (Immunoprecipitation)
Immunogen
Synthetized peptide (C-terminal cytoplasmic part of STIM1).
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-STIM1 antibody
STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet. Many questions also remain to be solved around STIM1 functional distribution. It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.
NCBI and Uniprot Product Information
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Product Notes
The STIM1 (Catalog #AAA128492) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-STIM1 Purified reacts with Rat, Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's STIM1 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the STIM1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STIM1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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