IHC (Immunohistochemisry)
(Anti-Hamartin antibody, AAA45371, IHC(P)IHC(P): Rat Brain Tissue)
Rabbit Hamartin Polyclonal Antibody | anti-TSC1 antibody
Anti-Hamartin antibody
Gene Names
TSC1; LAM; TSC
Reactivity
Reacts with : Human, RatPredicted to work with : Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Hamartin, Antibody; Anti-Hamartin antibody; Hamartin; tuberous sclerosis 1; Hamartin antibody; kiaa0243 antibody; LAM antibody; TSC antibody; TSC1 antibody; Tsc1 gene antibody; TSC1_HUMAN antibody; Tuberous sclerosis 1 antibody; Tuberous sclerosis 1 protein antibody; anti-TSC1 antibody
Host
Rabbit
Reactivity
Reacts with : Human, Rat
Predicted to work with : Mouse
Predicted to work with : Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
1164
Applicable Applications for anti-TSC1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Hamartin, identical to the related rat sequence, and different from the related mouse sequence by one amino acid
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Recommended Detection Systems
MBS recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (please inquire) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (please inquire) for IHC(P).
Preparation and Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemisry)
(Anti-Hamartin antibody, AAA45371, IHC(P)IHC(P): Rat Brain Tissue)
IHC (Immunohistochemisry)
(Anti-Hamartin antibody, AAA45371, IHC(P)IHC(P): Rat Brain Tissue)
IHC (Immunohiostchemistry)
(Anti-Hamartin antibody, AAA45371, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-Hamartin antibody, AAA45371, IHC(P)IHC(P): Human Mammary Cancer Tissue)
WB (Western Blot)
(Anti-Hamartin antibody, AAA45371, Western blottingAll lanes: Anti Hamartin (AAA45371) at 0.5ug/mlLane 1: Rat Skeletal Muscle Tissue Lysate at 50ugLane 2: Rat Heart Tissue Lysate at 50ugLane 3: Rat Brain Tissue Lysate at 50ugLane 4: Rat Lung Tissue Lysate at 50ugLane 5: 293T Whole Cell Lysate at 40ugLane 6: HELA Whole Cell Lysate at 40ugLane 7: HT1080 Whole Cell Lysate at 40ugLane 8: SMMC Whole Cell Lysate at 40ugPredicted bind size: 130KDObserved bind size: 160KD)
WB (Western Blot)
(Anti-Hamartin antibody, AAA45371, Western blottingAll lanes: Anti Hamartin (AAA45371) at 0.5ug/mlLane 1: Rat Skeletal Muscle Tissue Lysate at 50ugLane 2: Rat Heart Tissue Lysate at 50ugLane 3: Rat Brain Tissue Lysate at 50ugLane 4: Rat Lung Tissue Lysate at 50ugLane 5: 293T Whole Cell Lysate at 40ugLane 6: HELA Whole Cell Lysate at 40ugLane 7: HT1080 Whole Cell Lysate at 40ugLane 8: SMMC Whole Cell Lysate at 40ugPredicted bind size: 130KDObserved bind size: 160KD)
Related Product Information for anti-TSC1 antibody
Background: TSC1(Tuberous Sclerosis 1), also called HAMARTIN or TSC, is a human protein and gene. As part of a comprehensive strategy to identify the gene mutant in tuberous sclerosis-1, van Slegtenhorst et al.(1997) developed an overlapping contig of clones from the 1.4-Mb TSC1 region on chromosome 9. Benvenuto et al.(2000) showed that overexpression of the TSC1 gene in rat fibroblasts inhibits growth and causes changes in cell morphology. Van Slegtenhorst et al.(1998) showed that hamartin and tuberin associate physically in vivo, however, and that the interaction is mediated by predicted coiled-coil domains.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
124,015 Da
NCBI Official Full Name
Hamartin
NCBI Official Synonym Full Names
tuberous sclerosis 1
NCBI Official Symbol
TSC1
NCBI Official Synonym Symbols
LAM; TSC
NCBI Protein Information
hamartin; tumor suppressor; tuberous sclerosis 1 protein
UniProt Protein Name
Hamartin
UniProt Gene Name
TSC1
UniProt Synonym Gene Names
KIAA0243; TSC
UniProt Entry Name
TSC1_HUMAN
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Product Notes
The TSC1 tsc1 (Catalog #AAA45371) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Hamartin antibody reacts with Reacts with : Human, Rat Predicted to work with : Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Hamartin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TSC1 tsc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hamartin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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