WB (Western Blot)
( )
Rabbit TNK2 / ACK1 Polyclonal Antibody | anti-TNK2 antibody
Rabbit Polyclonal (IgG) to Human TNK2 / ACK1
Gene Names
TNK2; ACK; ACK1; ACK-1; p21cdc42Hs
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified
Synonyms
TNK2 / ACK1, Antibody; Rabbit Polyclonal (IgG) to Human TNK2 / ACK1; Anti-TNK2 / ACK1 Antibody (aa278-289) IHC-plus; TNK2; ACK; Activated p21cdc42Hs kinase; Ack kinase; ACK-1; ACK1; Activated CDC42 kinase 1; p21cdc42Hs; Human TNK2; anti-TNK2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Not tested with other proteins.
Purity/Purification
Purified
Form/Format
PBS, pH 7.4, 0.05% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
1038
Applicable Applications for anti-TNK2 antibody
ELISA, WB (Western Blot), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic peptide
Immunogen Type
Synthetic peptide
Antigen Modification
aa278-289
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
WB (Western Blot)
( )
WB (Western Blot)
( )
IHC (Immunohistochemistry)
(Anti-TNK2 / ACK1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 1.25 ug/ml.)
IHC (Immunohistochemistry)
(Anti-TNK2 / ACK1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 1.25 ug/ml.)
Related Product Information for anti-TNK2 antibody
ACK encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation pathway.
Product Categories/Family for anti-TNK2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
119,349 Da
NCBI Official Full Name
activated CDC42 kinase 1 isoform 1
NCBI Official Synonym Full Names
tyrosine kinase, non-receptor, 2
NCBI Official Symbol
TNK2
NCBI Official Synonym Symbols
ACK; ACK1; ACK-1; p21cdc42Hs
NCBI Protein Information
activated CDC42 kinase 1; activated p21cdc42Hs kinase; activated Cdc42-associated kinase 1; tyrosine kinase non-receptor protein 2
UniProt Protein Name
Activated CDC42 kinase 1
UniProt Gene Name
TNK2
UniProt Synonym Gene Names
ACK1; ACK-1
UniProt Entry Name
ACK1_HUMAN
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Product Notes
The TNK2 tnk2 (Catalog #AAA52272) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human TNK2 / ACK1 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TNK2 / ACK1 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TNK2 tnk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNK2 / ACK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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