Filters
▼Clonality
▼Type
▼Reactivity
▼Gene Name
▼Isotype
▼Host
▼Application
▼Clone
▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 1000-1050 of 2583 product results
IGF-1 LR3, Active Protein (Cat# AAA79323)
Full Name
Human IGF-1 LR3
Gene Names
IGF1; MGF; IGFI; IGF-I
Reactivity
Human
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing
FGFR-1/Fc Chimera, soluble, Active Protein (Cat# AAA79237)
Full Name
Human FGFR-1/Fc Chimera, soluble
Gene Names
FGFR1; CEK; FLG; HH2; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
Application Data
(Inhibition of the basic FGF-induced proliferation of HUVE cells by recombinant human sFGFR-1-Fc. HUVECs were stimulated with 10 ng/ml bFGF, the soluble receptor was added with a 50 - 200X excess)
FGFR-1/Fc Chimera, soluble, Active Protein (Cat# AAA79238)
Full Name
Human FGFR-1/Fc Chimera, soluble
Gene Names
FGFR1; CEK; FLG; HH2; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
Application Data
SCF, Active Protein (Cat# AAA79243)
Full Name
Mouse SCF
Gene Names
Kitl; Gb; SF; Sl; Clo; Con; Mgf; SCF; SLF; blz; Kitlg; contrasted
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
GDNF, Active Protein (Cat# AAA79245)
Full Name
Mouse GDNF
Gene Names
Gdnf; AI385739
Reactivity
Mouse
Purity
> 98% by SDS-PAGE and HPLC analyses
Pricing
Application Data
VEGF164, Active Protein (Cat# AAA79250)
Full Name
Mouse VEGF164
Gene Names
Vegfa; Vpf; Vegf
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Application Data
VEGFR-1/Flt-1 (D3), soluble, Active Protein (Cat# AAA79257)
Full Name
Human VEGFR-1/Flt-1 (D3), soluble
Gene Names
FLT1; FLT; FLT-1; VEGFR1; VEGFR-1
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
TGF-beta1, Active Protein (Cat# AAA79258)
Full Name
LTBP1
Gene Names
TGFB1; CED; LAP; DPD1; TGFB; TGFbeta
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analyses
Pricing
IGF-BP2, Active Protein (Cat# AAA79281)
Full Name
Human IGF-BP2
Gene Names
IGFBP2; IBP2; IGF-BP53
Reactivity
Human
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing
Application Data
LIF, Active Protein (Cat# AAA79285)
Full Name
Mouse LIF
Reactivity
Mouse
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Enterokinase, Active Protein (Cat# AAA79292)
Full Name
Human Enterokinase
Gene Names
TMPRSS15; ENTK; PRSS7
Purity
>90% by SDS-PAGE & HPLC analyses
Pricing
Application Data
VEGF164, Active Protein (Cat# AAA79293)
Full Name
Rat VEGF164
Gene Names
Vegfa; VPF; Vegf; VEGF-A; VEGF164
Reactivity
Rat
Purity
>95%, by SDS-PAGE and silver stain
Pricing
PAI2, Active Protein (Cat# AAA75570)
Full Name
PAI2 protein
Gene Names
SERPINB2; PAI; PAI2; PAI-2; PLANH2; HsT1201
Purity
> 95% pure
Pricing
PDGF CC, Active Protein (Cat# AAA75572)
Full Name
PDGF CC protein
Gene Names
PDGFC; SCDGF; FALLOTEIN
Purity
> 98% pure
Pricing
sFRP1, Active Protein (Cat# AAA75573)
Full Name
sFRP1 protein
Gene Names
SFRP1; FRP; FRP1; FrzA; FRP-1; SARP2
Purity
> or = 97% by SDS-PAGE and HPLC
Pricing
sDLL4, Active Protein (Cat# AAA75582)
Full Name
sDLL4 protein
Gene Names
DLL4; hdelta2
Purity
> 95% pure
Pricing
ELISA
(SARS COV2 S B.1.1.529 trimer ACE functional binding ELISA assay2019-ncov S B.1.1.529 trimer(coating at 0.1ug-well) binding with Human ACE2-Fc.The linear range was found to be 23 ng/ml)
SARS COV2 Spike protein S B.1.1.529 (omicron) Trimer, Active Protein (Cat# AAA76382)
Full Name
SARS COV2 Spike protein S B.1.1.529 (omicron) Trimer Recombinant
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
Application Data
(Polarized membrane extensions mediate osteoclast fusion.(D, top) Immunoblot analysis of lysates of RAW264.7 macrophages stimulated with RANKL for the indicated times with antibodies to Ser473-phosphorylated (p) or total forms of Akt.)
Soluble RANK ligand, Active Protein (Cat# AAA76383)
Full Name
Human Soluble RANK ligand Recombinant
Gene Names
TNFSF11; ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TRANCE; hRANKL2
Purity
>98%, as determined by SDS-PAGE and HPLC
Pricing
Application Data
((A) Nitrite production by HT-29 cells following 48 h of treatment with cytokines.Effect of 0–50 ng/ml TNF-? on nitrite production induced by 100 U/ml IFN-? and 10 ng/ml IL-1? in HT-29 cells following 48 h of treatment.)
Interferon-beta 1b, Active Protein (Cat# AAA76387)
Full Name
Human Interferon-beta 1b Recombinant
Gene Names
IFNB1; IFB; IFF; IFNB
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
Application Data
(Effects of ACM from Olig2PC-Astros and NPC-Astros on neurons.(h and i) RT-PCR analysis of the expression of the antioxidant defense-related genes, GCLC and NFE2L2 (n=3), and the neurotrophic growth factor genes, BDNF, GDNF and NT-3 (n=3).)
Glial-Derived Neurotrophic Factor, Active Protein (Cat# AAA76397)
Full Name
Mouse Glial-Derived Neurotrophic Factor Recombinant
Gene Names
Gdnf; AI385739
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
IL-13 alpha 2 receptor (IL13RA2), Active Protein (Cat# AAA76103)
Full Name
Human IL-13 alpha 2 receptor Recombinant (IL13RA2)
Purity
>98%, as determined by SDS-PAGE and HPLC
Pricing
CD200 (MOX1), Active Protein (Cat# AAA76111)
Full Name
Mouse CD200 Recombinant (MOX1)
Purity
>98%, as determined by SDS-PAGE and HPLC
Pricing
Bioactivity
(The activity was determined by immobilized Spike Protein S1 binding with human ACE2 in a functional ELISA assay, the ED50 was determined to be 3.8nM.2019-ncov S1-his tagged (coating at 0.5ug-well) binding with Human ACE2-Fc (cat. The linear range was found to be 0.1-5 ug/ml)
COVID 19 Spike S1 Coronavirus, Active Protein (Cat# AAA76120)
Full Name
2019 nCoV/COVID19 Spike protein S1 Recombinant-His
Purity
> 90% by SDS-PAGE.
Pricing
Pepsinogen I, Active Protein (Cat# AAA75592)
Full Name
Pepsinogen I protein
Purity
> 90% by SDS-PAGE
Pricing
IL21, Active Protein (Cat# AAA75599)
Full Name
IL21 protein
Gene Names
IL21; Za11; IL-21; CVID11
Purity
> 95.0% by SDS-PAGE
Pricing
Application Data
(Fig. 2: Dose-dependent stimulation of cell proliferation in NFS60 cells by recombinant human M-CSF. Values are the means (±SD) of triplicate determinations and expressed as percentage of control.)
M-CSF, Active Protein (Cat# AAA79123)
Full Name
Human M-CSF
Gene Names
CSF1; MCSF; CSF-1
Reactivity
Human
Purity
> 95% by SDS-PAGE
Pricing
ELISA
(Figure 2.Functional ELISA: Recombinant human PlGF-2 was coated with 0.5ug/ml and increasing amounts of recombinant human sFlt-1(5) was added as standard . The monoclonal mouse anti-human VEGFR1/Flt-1 antibody in combination with a goat anti-mouse Biotin antibody was used for detection.)
PlGF-2, Active Protein (Cat# AAA79127)
Full Name
Human PlGF-2
Gene Names
PGF; PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Application Data
GM-CSF, Active Protein (Cat# AAA79128)
Full Name
Human GM-CSF
Gene Names
CSF2; GMCSF
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Application Data
VEGFR-2/KDR (native), soluble, Active Protein (Cat# AAA79129)
Full Name
Human VEGFR-2/KDR (native), soluble
Gene Names
KDR; FLK1; CD309; VEGFR; VEGFR2
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Glu-C, Active Protein (Cat# AAA79131)
Full Name
Staphylococcus Glu-C
Reactivity
Staphylococcus
Purity
> 98% by SDS-PAGE & HPLC analysis
Pricing
Application Data
VEGF188, Active Protein (Cat# AAA79133)
Full Name
Mouse VEGF188
Gene Names
Vegfa; Vpf; Vegf
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
BioLISA
(Fig 2: Binding of sEGFRto recombinant human EGF in a functional ELISA. EGF [AAA79134] was coated with 200ng/well to a 96-well plate and sEGFR was added with increasing concentrations up to 4000ng/ml. Detection was performed using a polyclonal rabbit anti-human EGFR [] (1 ug/ml, 100 ul/well) and a goat anti-rabbit Biotin conjugated secondary antibody.)
EGFR, soluble, Active Protein (Cat# AAA79134)
Full Name
Human EGFR, soluble
Gene Names
EGFR; ERBB; HER1; mENA; ERBB1; PIG61
Reactivity
Human
Purity
> 90% by SDS-PAGE
Pricing
Application Data
VEGF165, Active Protein (Cat# AAA79135)
Full Name
Human VEGF165
Gene Names
VEGFA; VPF; VEGF; MVCD1
Reactivity
Human
Purity
> 95% by SDS-PAGE & visualized by silver stain
Pricing
Application Data
PlGF, Active Protein (Cat# AAA79139)
Full Name
Rat PlGF
Gene Names
Pgf; Plgf
Reactivity
Rat
Purity
> 95% by SDS-PAGE & silver stain
Pricing
CYR61, Active Protein (Cat# AAA79141)
Full Name
Human CYR61
Gene Names
CYR61; CCN1; GIG1; IGFBP10
Reactivity
Human
Purity
> 95% by SDS-PAGE and HPLC analysis
Pricing
Maltase Dehydrogenase, Active Protein (Cat# AAA78969)
Full Name
Maltase Dehydrogenase (Thermostable) (r-MDH)
Pricing
Application Data
SCF, Active Protein (Cat# AAA79148)
Full Name
Human SCF
Gene Names
KITLG; SF; MGF; SCF; FPH2; KL-1; Kitl; SHEP7
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Bioactivity
Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33L3, Active Protein (Cat# AAA177973)
Full Name
Recombinant Cynomolgus Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33L3 (C-6His)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Bioactivity
Thymic Stromal Lymphopoietin/TSLP, Active Protein (Cat# AAA177974)
Full Name
Recombinant Cynomolgus Thymic Stromal Lymphopoietin/TSLP (C-6His)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Application Data
TFF1, Active Protein (Cat# AAA214281)
Full Name
Recombinant Human TFF1
Gene Names
TFF1; pS2; BCEI; HPS2; HP1.A; pNR-2; D21S21
Purity
>95% as determined by SDS-PAGE
Pricing
STREPTOLYSIN-O, Active Protein (Cat# AAA50417)
Full Name
RECOMBINANT STREPTOLYSIN-O
Applications
ELISA
Pricing
WB (Western Blot)
(Western BlotSample: Recombinant FGF18, Human;Antibody: Rabbit Anti- Human FGF18 Ab)
Fibroblast Growth Factor 18 (FGF18), Active Protein (Cat# AAA150332)
Full Name
Active Fibroblast Growth Factor 18 (FGF18)
Applications
Activity Assay, Cell Culture
Purity
>98%
Pricing
SDS-PAGE
(SDS-PAGE)
Acid Sphingomyelinase (ASM), Active Protein (Cat# AAA152332)
Full Name
Active Acid Sphingomyelinase (ASM)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. Cell proliferation of TF-1 cells after stimulated with IL4.)
Interleukin 4 (IL4), Active Protein (Cat# AAA152970)
Full Name
Active Interleukin 4 (IL4)
Gene Names
IL4; IL-4; BSF-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
Growth Differentiation Factor 15 (hGDF15), Active Protein (Cat# AAA60569)
Full Name
Recombinant Mouse Growth Differentiation Factor 15 (hGDF15)
Purity
>95%, determined by SDS-PAGE
Pricing
Bioactivity
(HTRF assay for NEK2 activity 1 uM STK S3 substrate was incubated with different concentrations of NEK2 protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT, and 100 uM ATP for 1 hour. Then 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
Microtubule-associated tau (MAPT), Active Protein (Cat# AAA244040)
Full Name
Recombinant Human Microtubule-associated protein tau (MAPT)
Gene Names
MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
COVID 19 Spike Protein (S) D614G Coronavirus, Active Protein (Cat# AAA243741)
Full Name
Recombinant Human Novel Coronavirus Spike glycoprotein(S) (D614G), partial (Active)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized mouse EphA6 at 1 ug/ml (100 ul/well) can bind human EphrinA3 / Fc Chimera. The EC50 of human EphrinA3 is 299.2 ng/mL.)
Ephrin A3, Active Protein (Cat# AAA257840)
Full Name
Ephrin A3 Protein, Human, Recombinant (hFc Tag)
Gene Names
EFNA3; EFL2; EPLG3; LERK3; Ehk1-L
Purity
>95% as determined by SDS-PAGE
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.