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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 850-900 of 2567 product results
Glutathione S-Transferase, Active Protein (Cat# AAA38680)
Full Name
Recombinant Glutathione S-Transferase
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing
Thioredoxin Reductase 1, Active Protein (Cat# AAA38824)
Full Name
Recombinant Human Thioredoxin Reductase 1
Gene Names
TXNRD1; TR; TR1; TXNR; TRXR1; GRIM-12
Purity
Greater than 90% as determined by SDS-PAGE.
Pricing
ANGPTL-7, Active Protein (Cat# AAA76054)
Full Name
ANGPTL-7
Gene Names
ANGPTL7; AngX; CDT6; dJ647M16.1
Purity
>98%
IL2RA (CD25), Active Protein (Cat# AAA76070)
Full Name
Human IL2RA Recombinant (CD25)
Purity
>97%, as determined by SDS-PAGE and HPLC
Pricing
CD32b (FcgR2b), Active Protein (Cat# AAA76086)
Full Name
Human CD32b Recombinant (FcgR2b)
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
EGFL7, Active Protein (Cat# AAA76105)
Full Name
Human EGFL7 Recombinant
Purity
>90%, as determined by SDS-PAGE
Pricing
Application Data
(KRAS G12V (HLA-A*03:01) Tetramer SPRSPR image shows curve for KRAS G12V(HLA-A*03:01) and immobilized Antibody binding, with a calculated affinity constant of 42nM)
HLA-A*03:01 KRAS G12V, Active Protein (Cat# AAA76371)
Full Name
HLA-A*03:01 KRAS G12V peptide Tetramer
Purity
purity was determined to be >95% by nonreducing PAGE and HPLC
Pricing
Application Data
(Polarized membrane extensions mediate osteoclast fusion.(D, top) Immunoblot analysis of lysates of RAW264.7 macrophages stimulated with RANKL for the indicated times with antibodies to Ser473-phosphorylated (p) or total forms of Akt.)
Soluble RANK ligand, Active Protein (Cat# AAA76384)
Full Name
Mouse Soluble RANK ligand Recombinant
Gene Names
Tnfsf11; ODF; OPG; OPGL; RANKL; Ly109l; Trance
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
Application Data
(Generation of conditional TAK1-deficient mice.Colony formation by BM cells from Map3k7)
Granulocyte Colony Stimulating Factor, Active Protein (Cat# AAA76390)
Full Name
Mouse Granulocyte Colony Stimulating Factor Recombinant
Gene Names
Csf3; Csfg; G-CSF; MGI-IG
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
Application Data
(Expression of programmed death-1 (PD-1) in macrophages/microglia after spinal cord injury (SCI) in mice.Immunohistochemistry in macrophages/microglia 14 days postinjury (dpi) in wild-type mice for (c) PD-1, (d) it’s ligand, PD-L1, and (e) PD-1 in M1 cells [inducible nitric oxide synthase (iNOS)+]; (f) PD-1 in M2 cells [arginase 1 (Arg1+)]; (g) PD-L1 in M1 cells (iNOS+); and (h) PD-L1 in M2 cells (Arg1+).)
PD-L1 (B7-H1), Active Protein (Cat# AAA76402)
Full Name
Human PD-L1 (B7-H1) Recombinant
Gene Names
Cd274; B7h1; Pdl1; Pdcd1l1; Pdcd1lg1; A530045L16Rik
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
Application Data
LIF, Active Protein (Cat# AAA79124)
Full Name
Human LIF
Gene Names
LIF; CDF; DIA; HILDA; MLPLI
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
IL-4, Active Protein (Cat# AAA79151)
Full Name
Mouse IL-4
Gene Names
Il4; Il-4; BSF-1
Reactivity
Mouse
Purity
> 98% (SDS-PAGE; HPLC)
Pricing
TLR3, Active Protein (Cat# AAA75594)
Full Name
TLR3 protein
Purity
>95% by SDS-PAGE gel and HPLC analysis
Pricing
Sonic Hedgehog, Active Protein (Cat# AAA75584)
Full Name
Sonic Hedgehog protein
Gene Names
Shh; Hx; Dsh; Hhg1; Hxl3; M100081; 9530036O11Rik
Purity
> 98% pure
Pricing
BD4, Active Protein (Cat# AAA75586)
Full Name
BD4 protein
Gene Names
DEFB104A; BD-4; DEFB4; hBD-4; DEFB-4; DEFB104
Purity
> 98% pure
Pricing
Application Data
IL-2, Active Protein (Cat# AAA79197)
Full Name
Human IL-2
Gene Names
IL2; IL-2; TCGF; lymphokine
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
FGFR-2/Fc Chimera, soluble, Active Protein (Cat# AAA79217)
Full Name
Human FGFR-2/Fc Chimera, soluble
Gene Names
FGFR2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
Application Data
VEGF-F (Bothrops insularis), Active Protein (Cat# AAA79229)
Full Name
Snake VEGF-F (Bothrops insularis)
Reactivity
Snake
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Application Data
FGF-2 (basic), Active Protein (Cat# AAA79309)
Full Name
Rat FGF-2 (basic)
Gene Names
Fgf2; bFGF; Fgf-2
Reactivity
Rat
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Application Data
(Binding of recombinant human Wnt5a to recombinant human sROR2 in a functional ELISA. sROR2 was coated with 2ug/ml (100ug/well) and increasing amounts of Wnt5a was added. Detection was performed using a polyclonal rabbit anti-human Wnt5a and a goat anti-rabbit Biotin conjugated secondary antibody.)
ROR2, Active Protein (Cat# AAA79320)
Full Name
Human ROR2, soluble
Gene Names
ROR2; BDB; BDB1; NTRKR2
Reactivity
Human
Purity
> 98% by SDS-PAGE & Coomassie stain
Pricing
Application Data
VEGF144, Active Protein (Cat# AAA79241)
Full Name
Mouse VEGF144
Gene Names
Vegfa; Vpf; Vegf
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Application Data
VEGF121, Active Protein (Cat# AAA79263)
Full Name
Human VEGF121
Gene Names
VEGFA; VPF; VEGF; MVCD1
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Endostatin, Active Protein (Cat# AAA79266)
Full Name
Human Endostatin
Gene Names
COL18A1; KS; KNO; KNO1
Reactivity
Human
Purity
98 % (SDS-PAGE, HPLC)
Pricing
Application Data
VEGF164, Active Protein (Cat# AAA79269)
Full Name
Mouse VEGF164
Gene Names
Vegfa; Vpf; Vegf
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Application Data
(In vitro: The proliferative response to recombinant rat VEGF-CC152S was assayed in VEGFR3-expressing porcine aortic endothelial (PAE) cells. Briefly, cells were plated in 12-well plates and incubated in DMEM medium supplemented with 1% fetal calf serum for cell cycle arrest 24h prior to stimulation of cell proliferation with recombinant VEGF-CC152S at the concentrations of 50 and 100 ng/mL. After 48h in culture, the cell proliferative response was assayed (WST-1 colorimetric assay), and the results expressed as % of control non-stimulated cells (mean + sem).)
VEGF-C152S, Active Protein (Cat# AAA79274)
Full Name
Rat VEGF-C152S
Reactivity
Rat
Purity
> 90% by SDS-PAGE & silver stain
Pricing
Application Data
FGF-4, Active Protein (Cat# AAA79291)
Full Name
Human FGF-4
Gene Names
FGF4; HST; KFGF; HST-1; HSTF1; K-FGF; HBGF-4
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
GALECTIN-1, Active Protein (Cat# AAA50540)
Full Name
RECOMBINANT HUMAN GALECTIN-1
Gene Names
LGALS1; GBP; GAL1
Applications
Western Blot, Functional Assay
Purity
>98% by SDS PAGE/HPLC analysis
Pricing
Sequence
Nerve Growth Factor (NGF), Active Protein (Cat# AAA150972)
Full Name
Active Nerve Growth Factor (NGF)
Gene Names
Ngf; Ngfb; beta-NGF
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Sequence
Angiotensin I Converting Enzyme 2 (ACE2), Active Protein (Cat# AAA150976)
Full Name
Active Angiotensin I Converting Enzyme 2 (ACE2)
Gene Names
ACE2; ACEH
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
SDS-PAGE
(Figure. SDS-PAGE)
C ReProtein (CRP), Active Protein (Cat# AAA153060)
Full Name
Active C Reactive Protein (CRP)
Gene Names
Crp; AI255847
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. The chemotactic effect of ENA-78 on THP-1 cells)
Epithelial Neutrophil Activating Peptide 78 (ENA78), Active Protein (Cat# AAA153063)
Full Name
Active Epithelial Neutrophil Activating Peptide 78 (ENA78)
Gene Names
CXCL5; SCYB5; ENA-78
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
Bioactivity
(CD40, also known as Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5), is a 45-50 kDa type I transmembrane glycoprotein member of the TNF receptor superfamily. Mature human CD40 consists of a 173 amino acid (aa) extracellular domain, a transm)
Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40), Active Protein (Cat# AAA153079)
Full Name
Active Tumor Necrosis Factor Receptor Superfamily, Member 5 (CD40)
Gene Names
CD40; p50; Bp50; CDW40; TNFRSF5
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Complement Component 3 (C3) is a vital component of the complement system that plays a central role in immune response and inflammation. C3 is a beta? globulin synthesized by the liver, whose structure consists of two polypeptide chains, alpha and beta, and is the most abundant complement component in serum. It's been identified that C3 can interact with Complement Factor B (CFB), thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human C3 and recombinant mouse CFB. Briefly, CFB was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to C3-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-CFB pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. When Recombinant C3 is immobilized at 2 ug/mL (100 uL/well), the concentration of CFB that produces 50% optimal binding response is found to be approximately 5.96 ug/mL.)
Complement Component 3 (C3), Active Protein (Cat# AAA161793)
Full Name
Active Complement Component 3 (C3)
Gene Names
C3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a beta-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM). The activity of recombinant mouse RBP4 was measured by its ability to bind all-trans retinoic acid. The binding of retinoic acid results in the quenching of Trp fluorescence in RBP4. RBP4 was diluted to 50 ug/ml in 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, pH 7.5 (assay buffer) and the retinoic acid was diluted to 800, 400, 200, 100, 30, 10, 3, 1, 0.5 and 0.1 uM in 95% ethanol. Mixing 112.5 uL of 50 ug/mL rmRBP4 and 12.5 uL of retinoic acid serial dilutions in microtubes and a blank containing 112.5 uL of 50 ug/mL rmRBP4 and 12.5 uL of 95% ethanol, then incubate at room temperature for 30 minutes. Loading 100 ul of the reaction mixtures and blank and read at excitation and emission wavelengths of 280 nm and 340 nm (top read), respectively, in endpoint mode. The result was shown in figure 1, the 50% binding concentration (BC50) is > 4.6 uM.)
Retinol Binding Protein 4 (RBP4), Active Protein (Cat# AAA161806)
Full Name
Active Retinol Binding Protein 4 (RBP4)
Gene Names
Rbp4; Rbp-4
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Kallikrein 3, commonly known as prostate specific antigen (PSA), is a serine protease of the human tissue Kallikrein gene family. PSA is synthesized in the ductal and acinar epithelium of the prostate gland and secreted into the seminal plasma in high concentrations (0.5 - 2 g/L). A small portion of PSA "leaks" into the systemic circulation, the levels of which increase significantly (30-fold) from prostate cancer tissue than normal prostate tissue. PSA has become a well established tumor marker that aids the identification, staging, and follow up of prostate cancer. The activity of recombinant human KLK3 is measured by its ability to cleave a colorimetric peptide substrate Suc-Arg-Pro-Tyr-pNa in the assay buffer 50 mM Tris, 1 M NaCl, pH 8.0. The rhKLK3 is diluted to 200 ug/ml in activation buffer 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, 0.05% Brij-35, pH 7.5, then activated with a final concentration of 1 ug/ml Thermolysin at 37 degree C for 5min. Adding a final concentration of 10 mM 1,10 Phenanthroline to stop the activation. The activated rhKLK3 is diluted to 50 ug/mL in assay buffer. Loading into a clear well plate 50 uL of 50 ug/mL rhKLK3 and start the reaction by adding 50 uL of 2 mM substrate, with a substrate blank containing 50 uL assay buffer, 50 uL substrate, and no rhKLK3. Then read at 405 nm in kinetic mode for 5 minutes. The specific activity of recombinant human KLK3 is > 400 pmol/min/ug.)
Prostate Specific Antigen (PSA), Active Protein (Cat# AAA161711)
Full Name
Active Prostate Specific Antigen (PSA)
Gene Names
KLK3; APS; PSA; hK3; KLK2A1
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Annexin V (ANXA5) is a multifunctional protein that is highly expressed on the apical surfaces of syncytiotrophoblasts, and plays an important role in haemostatic regulations, maintaining blood fluidity of the placenta. Lower ANXA5 levels have been observed in M2/ANXA5 haplotype carrying chorion. The association found between the maternal carriage of the M2/ANXA5 haplotype and an elevated risk of IUGR and/or PE supports the hypothesis that carrier status of this haplotype and the consequently reduced placental ANXA5 expression might be responsible, at least partially, for the onset of these gestational vascular complications. Annexin V is a calcium-dependent phospholipid binding protein that can be used to bind Phosphatidylserine (PS) during an early apoptosis event where the PS becomes exposed at the cell surface. Jurkat cells were treated with 10 uM camptothecin for 4h, 2*105 cells which were resuspended in binding buffer were stained with 5 ug recombinant human Annexin V-GFP and 10 ul Propidium iodide (PI) for 20min in dark room temperature. The flow cytometry was used to detect the early apoptotic and late apoptotic of camptothecin-treated Jurkat cells (Figure 1), the combination of Annexin V-GFP and propidium iodide allows for the distinction between early apoptotic cells (Annexin V-FITC positive and propidium iodide negative), late apoptotic and/or necrotic cells (Annexin V-FITC and propidium iodide positive), and viable cells (unstained). Thus, the recombinant human Annexin V-GFP can bind Phosphatidylserine (PS) at early apoptosis of Jurkat.)
Annexin V (ANXA5), Active Protein (Cat# AAA161724)
Full Name
Active Annexin V (ANXA5)
Gene Names
ANXA5; PP4; ANX5; ENX2; RPRGL3; HEL-S-7
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Fas ligand (FasL) is a 40 kDa type II membrane protein belonging to the TNF family. In the new TNF super family nomenclature, FasL is referred to as TNFSF6. The specific receptor for FasL is Fas (CD95, Apo-1), a 45 kDa type I transmembrane protein that is a member of the TNF receptor family. FasL is predominantly expressed on activated T cells and NK cells, while Fas is expressed on various types of cells. The Fas/FasL system plays a crucial role in modulating immune response by inducing cell apoptosis to maintain homeostasis, self-tolerance of lymphocytes, and immune privilege. FasL was reported to be a potent chemoattractant for neutrophils, suggesting a novel proinflammatory function of this molecule. A functional ELISA assay was conducted to detect the interaction of recombinant human FASL and recombinant human FAS. Briefly, FASL was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to FAS-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-FASL pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630nm immediately. The binding activity of recombinant human FASL and recombinant human FAS was shown in Figure 1, the EC50 for this effect is 0.044 ug/mL.)
Factor Related Apoptosis Ligand (FASL), Active Protein (Cat# AAA161660)
Full Name
Active Factor Related Apoptosis Ligand (FASL)
Gene Names
FASLG; APTL; FASL; CD178; CD95L; ALPS1B; CD95-L; TNFSF6; APT1LG1
Applications
Activity Assay, Cell Culture
Purity
Greater than 80% by SDS-PAGE
Pricing
Bioactivity
Peptidase M20 Domain-containing Protein 1 (mPM20D1), Active Protein (Cat# AAA60568)
Full Name
Recombinant Mouse Peptidase M20 Domain-containing Protein 1 (mPM20D1)
Purity
>95%, determined by SDS-PAGE
Pricing
interleukin 22 receptor antagonist, Active Protein (Cat# AAA60572)
Full Name
Human interleukin 22 receptor antagonist (Y51A)
Gene Names
IL22; TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; TIFIL-23
Purity
Greater than 98.0% as determined by:
(a) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
(b) Gel filtration chromatography under non-denaturing conditions.
(a) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
(b) Gel filtration chromatography under non-denaturing conditions.
Bovine Type I Collagen Substrate, Active Protein (Cat# AAA60516)
Full Name
Bovine Type I Collagen Substrate, FITC Conjugate
Purity
Purified protein
Pricing
Granulocyte-Colony Stimulating Factor, Active Protein (Cat# AAA38114)
Full Name
Recombinant Human Granulocyte-Colony Stimulating Factor
Gene Names
CSF3; GCSF; CSF3OS; C17orf33
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Interleukin-2, Active Protein (Cat# AAA38188)
Full Name
Recombinant Porcine Interleukin-2
Gene Names
IL2; IL-2; TCGF; POIL2
Purity
Greater than 96.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing
Neuregulin-1/Heregulin-b2, Active Protein (Cat# AAA38192)
Full Name
Recombinant Human Neuregulin-1/Heregulin-b2
Gene Names
NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2
Purity
Greater than 96.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
BD2, Active Protein (Cat# AAA75442)
Full Name
BD2 protein
Gene Names
DEFB4A; BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102
Purity
> 98% pure
Pricing
Cathepsin G, Active Protein (Cat# AAA75222)
Full Name
Cathepsin G protein
Gene Names
CTSG; CG; CATG
Purity
>95% pure by SDS-PAGE
Pricing
Interleukin-3, Active Protein (Cat# AAA38782)
Full Name
Recombinant Canine Interleukin-3
Gene Names
IL3; IL-3; MCGF
Purity
Greater than 97.0% as determined by: (a) Analysis by HPLC. (b) Analysis by SDS-PAGE.
Pricing
Zebrafish Growth Hormone, Active Protein (Cat# AAA38832)
Full Name
Recombinant Zebrafish Growth Hormone
Purity
Greater than 99.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Interleukin-11, Active Protein (Cat# AAA38774)
Full Name
Recombinant Mouse Interleukin-11
Gene Names
Il11; IL-11
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Fibroblast Growth Factor-9, Active Protein (Cat# AAA38196)
Full Name
Recombinant Human Fibroblast Growth Factor-9
Gene Names
FGF9; GAF; FGF-9; SYNS3; HBFG-9; HBGF-9
Purity
Greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.