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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 950-1000 of 2875 product results
Application Data
FGF-4, Active Protein (Cat# AAA79206)
Full Name
Mouse FGF-4
Gene Names
Fgf4; KS3; hst; Fgfk; Hst1; kFGF; Fgf-4; hst-1; Hstf-1
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
WB (Western Blot)
(Western Blot: NP HIS Tag detected with Covid-19 positive patient serum)
COVID 19 Nucleocapsid (NP) Coronavirus, Active Protein (Cat# AAA58642)
Full Name
Recombinant Human SARS-CoV-2 Nucleoprotein (HEK)
Purity
Affinity chromatography. Purity: >95% by SDS PAGE
Pricing
Carboxylesterase 1D, Active Protein (Cat# AAA39142)
Full Name
Recombinant Mouse Carboxylesterase 1D
Gene Names
Ces1d; TGH; Ces3
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing
Beta Defensin -3, Active Protein (Cat# AAA38981)
Full Name
Recombinant Mouse Beta Defensin -3
Gene Names
Defb3; BD-3
Purity
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing
Bioactivity
(Figure. The binding activity of Hepc with FPN.Hepcidin (Hepc) is a regulator of iron metabolism. Hepcidin inhibits iron transport by binding to the iron export channel ferroportin which is located on the basolateral surface of gut enterocytes and the plasma membrane of reticuloendothelial cells (macrophages). Hepcidin ultimately breaks down the transporter protein in the lysosome. Inhibiting ferroportin prevents iron from being exported and the iron is sequestered in the cells. Besides, Ferroportin (FPN) has been identified as an interactor of Hepc, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Hepc and recombinant human FPN. Briefly, Hepc were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to FPN-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-Hepc pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of Hepc and FPN was shown in Figure 1, and this effect was in a dose dependent manner.)
Hepcidin, Active Protein (Cat# AAA150123)
Full Name
Active Hepcidin (Hepc)
Gene Names
HAMP; HEPC; PLTR; HFE2B; LEAP1
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
WB (Western Blot)
(Sample: Recombinant RNASEP, Rat;Antibody: Rabbit Anti-Rat RNASEP Ab)
Ribonuclease P (RNASEP), Active Protein (Cat# AAA148167)
Full Name
Active Ribonuclease P (RNASEP)
Reactivity
Rattus norvegicus (Rat)
Applications
Activity Assay, Cell Culture
Purity
>98%
Pricing
SDS-PAGE
Interleukin 25 (IL25), Active Protein (Cat# AAA148228)
Full Name
Active Interleukin 25 (IL25)
Gene Names
IL25; IL17E
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Bioactivity
(Carbonic anhydrase catalyzes the reversible reaction of CO2 H2O = HCO3- H, which is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Carbonic Anhydrase VII encoded by the CA7 gene is a cytosolic protein predominantly expressed in the salivary gland. CA7 may have additional tissue distributions and functions. For example, studies with CA inhibitors provide evidence that human CA7 is the CA isozyme responsible for the anticonvulsant/antiepileptic activity of sulfonamides and sulfamates. In fact, CA7 has been shown in a rat model to act as a developmental switch in GABAergic signaling in neurons. The activity of recombinant mouse CA7 was measured by its ability to hydrolyze 4-Nitrophenyl acetate (4-NPA) to 4-Nitrophenol. The reaction was performed in 12.5 mM Tris, 75 mM NaCl, pH 7.5 (assay buffer), initiated by addition 50 uL of various concentrations of CA7 (diluted by assay buffer) to 50 uL of 2 mM substrate 4-NPA (100 mM stock in Acetone, diluted by assay buffer). Incubated at 37 degree C for 5min, then read at a wavelength of 400 nm.)
Carbonic Anhydrase VII (CA7), Active Protein (Cat# AAA161904)
Full Name
Active Carbonic Anhydrase VII (CA7)
Gene Names
Car7; Ca7; AV343731
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(IFNgamma R2 (Interferon gamma receptor 2; also called IFN gamma R beta IFN gamma RII, or AF1) is a 6064 kDa type I transmembrane glycoprotein that is a member of the class II cytokine receptor family of molecule). It is highly expressed on the surfaces of myeloid cells, moderately expressed on B cells, and poorly expressed on the surfaces of T cells. IFNgammaR2 is a cell-surface receptor that is required for interferon-gamma signalling and therefore plays a critical immunoregulatory role in innate and adaptive immunity against viral and also bacterial and protozoal infections. IFNgR2 have been confirmed to mediate down-stream JAK-STAT signaling pathway in mammals. It is widely expressed as part of a preassembled cell surface multimeric complex. In the absence of IFNgamma, the complex contains two each of IFNgamma R1, R2 and Jak1 molecules. Binding of IFNgamma to IFNgamma R1 recruits Jak2 to IFN-gamma R2 and initiates phosphorylation, STAT1 binding, conformational changes and transcriptional regulation, which mainly inhibits proliferation and/or promotes apoptosis. A functional binding ELISA assay was conducted to detect the interaction of recombinant human IFNgR2 and recombinant rat JAK2. Briefly, biotin-linked IFNgR2 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to JAK2-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST 3 times and incubation with Streptavidin-HRP for 30min, then wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 ul stop solution to the wells and read at 450 nm immediately. The binding activity of IFNgR2 and JAK2 was shown in Figure 1, the EC50 for this effect is 1.02 ug/mL.)
Interferon Gamma Receptor 2 (IFNgR2), Active Protein (Cat# AAA161936)
Full Name
Active Interferon Gamma Receptor 2 (IFNgR2)
Gene Names
IFNGR2; AF-1; IFGR2; IFNGT1
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
SDS-PAGE
(SDS-PAGE of ~14 kDa Active Human Recombinant Alpha Synuclein Protein Aggregate. Lane 1: Molecular Weight Ladder (MW). Lane 2: Active Alpha Synuclein Protein Aggregate.)
Alpha Synuclein, Active Protein (Cat# AAA253923)
Full Name
Alpha Synuclein Protein
Gene Names
SNCA; PD1; NACP; PARK1; PARK4
Applications
Western Blot
Purity
>95%
Ion-exchange Purified
Ion-exchange Purified
Pricing
Application Data
(Measured by its ability to inhibit NGF-induced proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.2-0.8 ug/ml in the presence of 10 ng/mL of Recombinant human NGF.)
TrkA, Active Protein (Cat# AAA257961)
Full Name
TrkA Protein, Human, Recombinant (aa 285-413, His Tag)
Gene Names
NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
Purity
>97% as determined by SDS-PAGE
Pricing
Interleukin-27 p28, Active Protein (Cat# AAA39117)
Full Name
Recombinant Human Interleukin-27 p28
Gene Names
IL27; p28; IL30; IL-27; IL27A; IL-27A; IL27p28
Purity
Greater than 90% as determined by analysis by SDS-PAGE.
Pricing
prolactin receptor antagonist, Active Protein (Cat# AAA39185)
Full Name
Human prolactin receptor antagonist - SUPER ACTIVE
Purity
Greater than 97.0% as determined by: (a) Gel filtration analysis (size exclusion chromtography). (b) Analysis by reducing and non-reducing SDS-PAGE gel.
Pricing
Interleukin-21, Active Protein (Cat# AAA38193)
Full Name
Recombinant Human Interleukin-21
Gene Names
IL21; Za11; IL-21; CVID11
Purity
Greater than 97.0% as determined by SDS-PAGE.
Pricing
BLeptin, Active Protein (Cat# AAA38233)
Full Name
Recombinant Bovine Leptin
Gene Names
LEP; ob
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Application Data
VEGF164, Active Protein (Cat# AAA79312)
Full Name
Mouse VEGF164
Gene Names
Vegfa; Vpf; Vegf
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
SDS-PAGE
Interleukin-3, Active Protein (Cat# AAA48476)
Full Name
Interleukin-3, 20-152aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
IL3; IL-3; MCGF; MULTI-CSF
Applications
SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing
Bioactivity
(CD200 Subunit is coated at 10 ug/ml (100 ul/well) can bind Human CD200R1 (CAT# ATGP3809) in a Functional ELISA assay.)
CD200, Active Protein (Cat# AAA48391)
Full Name
Recombinant human CD200 protein
Gene Names
CD200; MRC; MOX1; MOX2; OX-2
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
Bioactivity
CD28/TP44, Active Protein (Cat# AAA177933)
Full Name
Recombinant Human/Cynomolgus CD28/TP44 (N-His)
Gene Names
CD28; Tp44
Purity
>95% as determined by reducing SDS-PAGE
Pricing
SDS-PAGE
ADAM15 / MDC15, Active Protein (Cat# AAA173583)
Full Name
Recombinant Mouse ADAM15 / MDC15 Protein (His tag)
Gene Names
Adam15; AD56; MDC15
Purity
> 90 % as determined by SDS-PAGE
Pricing
Bioactivity
(Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP-1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by keratinocytes, monocytes, macrophages and PMN leukocytes. MMP-9 is present in most cases of inflammatory responses. The activity of recombinant human MMP9 is measured by its ability to cleave a fluorogenic peptide substrate MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 in the assay buffer 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, 0.05% (w/v) Brij-35, pH 7.5. The rhMMP9 is diluted to 100 ug/ml in assay buffer, then activated by p-aminophenylmercuric acetate (APMA) in a final concentration of 1 mM incubated at 37 degree C for 1 hours. The activated rhMMP9 is diluted to 0.2 ug/mL in assay buffer. Loading into a black well plate 50 uL of 0.2 ug/mL rhMMP9 and start the reaction by adding 50 uL of 20 uM substrate, with a substrate blank containing 50 uL assay buffer, 50 uL substrate, and no rhMMP9. Then read at excitiation and emission wavelengths of 320 nm and 405 nm, respectively, in kinetic mode for 5 minutes. The specific activity of recombinant human MMP9 is > 3000 pmol/min/ug.)
Matrix Metalloproteinase 9 (MMP9), Active Protein (Cat# AAA161746)
Full Name
Active Matrix Metalloproteinase 9 (MMP9)
Gene Names
MMP9; GELB; CLG4B; MMP-9; MANDP2
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Tryptase is a serine protease with trypsin-like activity, which is sometimes also referred to as Mast Cell Protease 7. It is stored in the secretory granules of mouse mast cells. It exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of the diverse array of protease inhibitors in plasma. The activity of recombinant human TPS is measured by its ability to cleave a fluorogenic peptide substrate Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(Dnp)-NH2 in the assay buffer 50 mM Tris, pH 8.5. The rhTPS is diluted to 200 ug/ml in 50 mM Tris, 150 mM NaCl, 10 mM CaCl2, 0.05% (w/v) Brij-35, pH 7.5, then activated with 0.1 ug/ml Thermolysin at 37 degree C for 15min followed by adding 10 mM 1, 10 phenanthroline to stop activation. The activated rhTPS is diluted to 50 ug/mL in heparin incubation buffer of 100 ug/mL heparin, 50 mM MES, pH 5.5 and incubated at room temperature for 2 hours. Then the rhTPS was diluted to 12.5 ug/ml in assay buffer and load into a black well plate 50 uL and start the reaction by adding 50 uL of 20 uM substrate, with a substrate blank containing 50 uL assay buffer, 50 uL substrate, and no rhTPS. Then read at excitiation and emission wavelengths of 320 nm and 405 nm, respectively, in kinetic mode for 5 minutes. The specific activity of recombinant human TPS is > 25 pmol/min/ug.)
Tryptase (TPS), Active Protein (Cat# AAA161828)
Full Name
Active Tryptase (TPS)
Gene Names
TPSAB1; TPS1; TPS2; TPSB1
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(IL-2(Interleukin-2) is a cytokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2 is a type of signaling molecule in the immune system, that is required for both T-cell and B-cell proliferation and other activities crucial to r)
Interleukin 2 (IL2), Active Protein (Cat# AAA152967)
Full Name
Active Interleukin 2 (IL2)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. The hemagglutination assay of GAL9 in V- bottom shaped 96-well microtiter plate.)
Galectin 9 (GAL9), Active Protein (Cat# AAA153024)
Full Name
Active Galectin 9 (GAL9)
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human CD55 at 2 ug/ml (100 ul/well) can bind human CD97 with a linear ranger of 1.28-32 ng/ml.)
CD97, Active Protein (Cat# AAA257973)
Full Name
CD97 Protein, Human, Recombinant (hFc Tag)
Gene Names
ADGRE5; CD97; TM7LN1
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
FGF10, Active Protein (Cat# AAA214219)
Full Name
Recombinant Human FGF10
Purity
>95% as determined by SDS-PAGE
Pricing
Bioactivity
(Figure 1. The binding activity of FABP4 with ACTb)
Fatty Acid Binding Protein 4, Active Protein (Cat# AAA150114)
Full Name
Active Fatty Acid Binding Protein 4 (FABP4)
Gene Names
FABP4; aP2; ALBP; AFABP; A-FABP; HEL-S-104
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Procalcitonin, Active Protein (Cat# AAA38672)
Full Name
Recombinant Human Procalcitonin
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
Interleukin 1 Family, Active Protein (Cat# AAA38915)
Full Name
Recombinant Human Interleukin 1 Family, Member 10
Gene Names
IL1F10; IL-38; FKSG75; IL1HY2; IL-1HY2; IL1-theta; FIL1-theta
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Galectin-1, Active Protein (Cat# AAA38590)
Full Name
Recombinant Human Galectin-1
Gene Names
LGALS1; GBP; GAL1
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Fibroblast Growth Factor-basic, Active Protein (Cat# AAA38184)
Full Name
Recombinant Mouse Fibroblast Growth Factor-basic
Gene Names
Fgf2; Fgfb; bFGF; Fgf-2
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Bioactivity
(Human CD40 Ligand/TNFSF5 is coated at 5 ug/ml (100 ul/well) can bind Human CD40/TNFRSF5 (CAT# ATGP4007) in a Functional ELISA assay.)
CD40 Ligand/TNFSF5, Active Protein (Cat# AAA48396)
Full Name
Recombinant human CD40 Ligand/TNFSF5 protein
Gene Names
CD40LG; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
SDS-PAGE
Prdx1, Active Protein (Cat# AAA48922)
Full Name
Prdx1, 1-199aa, Mouse, His tag, Baculovirus (Bioactivity Validated)
Gene Names
Prdx1; PAG; OSF3; Paga; PrxI; TDX2; TPxA; prx1; MSP23; NkefA; OSF-3; PrdxI; Tdpx2
Applications
Enzyme Activity, SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.)
Eno1, Active Protein (Cat# AAA48970)
Full Name
Eno1, 1-434aa, Mouse, His-tag, E Coli (Bioactivity Validated)
Gene Names
Eno1; Eno-1; MBP-1; AL022784; 0610008I15
Applications
Enzyme Activity, SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing
Neurturin, Active Protein (Cat# AAA79278)
Full Name
Human Neurturin
Gene Names
NRTN; NTN
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analysis
Pricing
NNT-1/BCSF-3, Active Protein (Cat# AAA79298)
Full Name
Human NNT-1/BCSF-3
Gene Names
CLCF1; CLC; NR6; BSF3; NNT1; BSF-3; CISS2; NNT-1
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analysis
Pricing
Growth Hormone, Active Protein (Cat# AAA38106)
Full Name
Recombinant Human Growth Hormone
Gene Names
GH1; GH; GHN; GH-N; hGH-N; IGHD1B
Purity
Greater than 96.0% as determined by SDS-PAGE.
Pricing
Fibroblast Growth Factor Receptor-2, Active Protein (Cat# AAA38396)
Full Name
Recombinant Human Fibroblast Growth Factor Receptor-2
Gene Names
FGFR2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
Purity
Greater than 90.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
SDS-PAGE
GSTM1, Active Protein (Cat# AAA48521)
Full Name
GSTM1, 1-218aa, Mouse, E Coli (Bioactivity Validated)
Gene Names
Gstm1; Gstb1; Gstb-1
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
SDS-PAGE
MDH1, Active Protein (Cat# AAA48570)
Full Name
MDH1, 1-334aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
MDH1; MDHA; MOR2; MDH-s; HEL-S-32; MGC:1375
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Bioactivity
(Carbonic Anhydrase (CA) catalyzes the reversible reaction of CO2 H2O = HCO3- H, which is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. CA8, also called CArelated protein (CARP), is a cytosolic protein without CA activity (i.e., the reversible hydration of CO2) due to point mutations in the zinc-binding site. CA8 is expressed exclusively in Purkinje cells of the cerebellum, where it binds inositol 1,4,5-triphosphate receptor type 1. CA8 overexpression in human colorectal cancer and non-small cell lung cancer indicates that it plays a role in the process of invasion in these types of malignancy. The activity of recombinant human CA8 was measured by its ability to hydrolyze 4-Nitrophenyl acetate (4-NPA) to 4-Nitrophenol. The reaction was performed in 12.5 mM Tris, 75 mM NaCl, pH 7.5 (assay buffer), initiated by addition 50 uL of various concentrations of CA8 (diluted by assay buffer) to 50 uL of 2 mM substrate 4-NPA (100 mM stock in Acetone, diluted by assay buffer). Incubated at 37 degree C for 5min, then read at a wavelength of 400 nm.)
Carbonic Anhydrase VIII (CA8), Active Protein (Cat# AAA161905)
Full Name
Active Carbonic Anhydrase VIII (CA8)
Gene Names
CA8; CALS; CARP; CAMRQ3; CA-VIII
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
WB (Western Blot)
(Load: 3 ug)
Streptolysin O, Active Protein (Cat# AAA224745)
Full Name
Purified recombinant Streptolysin O protein
Purity
99% by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human HHLA2h at 10 ug/mL (100 uL/well) can bind human TMIGD2-Fc3, the EC50 of human TMIGD2-Fc3 is 50-200 ng/mL.)
TMIGD2, Active Protein (Cat# AAA258027)
Full Name
TMIGD2 Protein, Human, Recombinant (ECD, hFc Tag)
Gene Names
TMIGD2; CD28H; IGPR1; IGPR-1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured in a cytotoxicity assay using L929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 1-5 ng/mL.)
TNF-alpha, Active Protein (Cat# AAA257901)
Full Name
TNF-alpha Protein, Human, Recombinant (hFc Tag)
Gene Names
TNF; DIF; TNFA; TNFSF2; TNF-alpha
Purity
>90% as determined by SDS-PAGE
Pricing
Growth and Differentiation factor 7, Active Protein (Cat# AAA37990)
Full Name
Recombinant Human Growth and Differentiation factor 7
Gene Names
GDF7; BMP12
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
Noggin, Active Protein (Cat# AAA38222)
Full Name
Recombinant Human Noggin
Gene Names
NOG; SYM1; SYNS1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
Endostatin, Active Protein (Cat# AAA38418)
Full Name
Recombinant Human Endostatin
Gene Names
COL18A1; KS; KNO; KNO1
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing
FGFR-2/Fc Chimera, soluble, Active Protein (Cat# AAA79161)
Full Name
Human FGFR-2/Fc Chimera, soluble
Gene Names
FGFR2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
Application Data
FGF-4, Active Protein (Cat# AAA79290)
Full Name
Human FGF-4
Gene Names
FGF4; HST; KFGF; HST-1; HSTF1; K-FGF; HBGF-4
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
SDS-PAGE
Pyrethroid hydrolase Ces2e, Active Protein (Cat# AAA48914)
Full Name
Pyrethroid hydrolase Ces2e, 27-559aa, Mouse, His tag, Baculovirus (Bioactivity Validated)
Gene Names
Ces2e; Ces5; 9030624L02Rik
Applications
Enzyme Activity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.
All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Learn more in our guide “How active proteins work”.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.