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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 950-1000 of 2583 product results


product-image-AAA161695_BIOACTIVITY13.jpg Bioactivity (Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the family, TIMP-1, TIMP-2, TIMP-3, and TIMP-4. TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes. TIMP-2 also has erythroidpotentiating and cell growth promoting activities. The activity of recombinant bovine TIMP2 was measured by its ability to inhibit rhMMP2 cleavage of a fluorogenic peptide substrate MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 in the assay buffer 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, 0.05% (w/v) Brij-35, pH 7.5. rhMMP2 was diluted to 100 ug/ml and activated with 1 mM APMA at 37 degree C for 1 hour and rbTIMP2 (MW: 51.75 KD) was diluted to different concentrations with the assay buffer. Mix 8 ul of rhTIMP2 curve dilutions, 12.8 ul of activated rbMMP-2, and 59.2 ul of assay buffer, including a control containing assay buffer and the diluted rhMMP-2 and incubate the reactions for 2 hours at 37 degree C. Loading 50 ul of the incubated mixtures which were diluted five-fold in assay buffer into empty wells of a plate, and start the reaction by adding 50 ul of 20 uM substrate. Include a substrate blank containing 50 ul of assay buffer and 50 ul of 20 uM substrate. Then read at excitiation and emission wavelengths of 320 nm and 405 nm, respectively, in kinetic mode for 5 minutes. The result was shown in Figure 1 and it was obvious that recombinant bovine TIMP2 significantly decreased rhMMP2 activity. The inhibition IC50 was )

Tissue Inhibitors Of Metalloproteinase 2 (TIMP2), Active Protein (Cat# AAA161695)

Full Name
Active Tissue Inhibitors Of Metalloproteinase 2 (TIMP2)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153011_BIOACTIVITY13.jpg Bioactivity (Annexin V (ANXA5) is a multifunctional protein that is highly expressed on the apical surfaces of syncytiotrophoblasts, and plays an important role in haemostatic regulations, maintaining blood fluidity of the placenta. Lower ANXA5 levels have been observ)

Annexin V (ANXA5), Active Protein (Cat# AAA153011)

Full Name
Active Annexin V (ANXA5)
Gene Names
Anxa5; Anx5; R74653
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153050_BIOACTIVITY13.jpg Bioactivity (Apolipoprotein A2 (APOA2) is a major protein component of serum HDL. It is produced by the liver and is involved in cholesteryl ester formation and cholesterol transport from tissues to the liver. Polymorphisms of APOA2 are associated with disorders of ch)

Apolipoprotein A2 (APOA2), Active Protein (Cat# AAA153050)

Full Name
Active Apolipoprotein A2 (APOA2)
Gene Names
APOA2; apoAII; Apo-AII; ApoA-II
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153078_BIOACTIVITY13.jpg Bioactivity (Aspartate transaminase(AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or glutamic oxaloacetic transaminase, is a pyridoxal phosphate-dependent transaminase enzyme AST catalyzes the reversible transfer of an alpha-amino group between aspa)

Aspartate Aminotransferase (AST), Active Protein (Cat# AAA153078)

Full Name
Active Aspartate Aminotransferase (AST)
Gene Names
Got1; cCAT; Got-1; cAspAT; AI789014
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA173583_SDS_PAGE15.jpg SDS-PAGE

ADAM15 / MDC15, Active Protein (Cat# AAA173583)

Full Name
Recombinant Mouse ADAM15 / MDC15 Protein (His tag)
Gene Names
Adam15; AD56; MDC15
Purity
> 90 % as determined by SDS-PAGE
Pricing
product-image-AAA177933_BIOACTIVITY13.jpg Bioactivity

CD28/TP44, Active Protein (Cat# AAA177933)

Full Name
Recombinant Human/Cynomolgus CD28/TP44 (N-His)
Gene Names
CD28; Tp44
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA177939_BIOACTIVITY13.jpg Bioactivity

Interleukin-36 alpha/IL-36 alpha, Active Protein (Cat# AAA177939)

Full Name
Recombinant Human Interleukin-36 alpha/IL-36 alpha
Gene Names
IL36A; FIL1; FIL1E; IL1F6; IL-1F6; IL1(EPSILON); FIL1(EPSILON)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA177975_BIOACTIVITY13.jpg Bioactivity

Signal-Regulatory Protein alpha-1/SIRPA/CD172a, Active Protein (Cat# AAA177975)

Full Name
Recombinant Cynomolgus Signal-Regulatory Protein alpha-1/SIRPA/CD172a (C-6His)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA177976_BIOACTIVITY13.jpg Bioactivity

Interleukin-17A/IL-17A, Active Protein (Cat# AAA177976)

Full Name
Recombinant Cynomolgus Interleukin-17A/IL-17A (C-6His)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA176991_WB15.jpg WB (Western Blot)

COVID 19 Spike S Protein (RBD) Coronavirus, Active Protein (Cat# AAA176991)

Full Name
Recombinant 2019-nCoV Spike S Protein (RBD, mFc Tag)
Purity
> 95 % as determined by reducing SDS-PAGE.
Pricing

PHOSPHORYLASE B, Active Protein (Cat# AAA50505)

Full Name
NATIVE RABBIT PHOSPHORYLASE B
Applications
ELISA
Purity
Protein: 95%
Pricing
product-image-AAA150068_AD11.png Application Data (Figure. The chemotactic effect of recombinant human MIP3b on Jurkat cells.)

Macrophage Inflammatory Protein 3 Beta, Active Protein (Cat# AAA150068)

Full Name
Active Macrophage Inflammatory Protein 3 Beta (MIP3b)
Gene Names
CCL19; ELC; CKb11; MIP3B; MIP-3b; SCYA19
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
product-image-AAA150071_BIOACTIVITY10.png Bioactivity (Figure. The binding activity of PK2 with PKR1)

Prokineticin 2, Active Protein (Cat# AAA150071)

Full Name
Active Prokineticin 2 (PK2)
Gene Names
PROK2; BV8; HH4; PK2; KAL4; MIT1
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150082_BIOACTIVITY10.jpg Bioactivity (Ribonuclease P (RNASEP) is a type of ribonuclease which cleaves RNA. RNase P is unique from other RNases in that it is a ribozyme – a ribonucleic acid that acts as a catalyst in the same way that a protein based enzyme would. Its function is to cleave off an extra, or precursor, sequence of RNA on tRNA molecules. Besides, Methyl CpG Binding Protein 2 (MECP2) has been identified as an interactor of RNASEP, thus a binding ELISA assay was conducted to detect the interaction of recombinant human RNASEP and recombinant human MECP2. Briefly, RNASEP were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to MECP2-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-RNASEP pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of RNASEP and MECP2 was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of RNASEP with MECP2.)

Ribonuclease P, Active Protein (Cat# AAA150082)

Full Name
Active Ribonuclease P (RNASEP)
Gene Names
RPP40; RNASEP1; bA428J1.3
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
product-image-AAA150091_AD11.jpg Application Data (Figure. Cell proliferation of 3T3 cells after stimulated with EGF.)

Epidermal Growth Factor, Active Protein (Cat# AAA150091)

Full Name
Active Epidermal Growth Factor (EGF)
Gene Names
Egf; AI790464
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150115_BIOACTIVITY11.png Bioactivity (Figure. The binding activity of UGCG with LMP2.)

UDP Glucose Ceramide Glucosyltransferase, Active Protein (Cat# AAA150115)

Full Name
Active UDP Glucose Ceramide Glucosyltransferase (UGCG)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150130_WB13.png WB (Western Blot) (Figure. Western Blot)

Platelet Derived Growth Factor D, Active Protein (Cat# AAA150130)

Full Name
Active Platelet Derived Growth Factor D (PDGFD)
Gene Names
PDGFD; IEGF; SCDGFB; MSTP036; SCDGF-B
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
product-image-AAA150135_BIOACTIVITY10.jpg Bioactivity (Figure. The binding activity of GDNF with GFRa2.Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons. This protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. GDNF is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Besides, Glial Cell Line Derived Neurotrophic Factor Receptor Alpha 2 (GFRa2) has been identified as an interactor of GDNF, thus a binding ELISA assay was conducted to detect the interaction of recombinant human GDNF and recombinant human GFRa2. Briefly, GDNF were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to GFRa2-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-GDNF pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of GDNF and GFRa2 was shown in Figure 1, and this effect was in a dose dependent manner.)

Regenerating Islet Derived Protein 3 Alpha, Active Protein (Cat# AAA150135)

Full Name
Active Regenerating Islet Derived Protein 3 Alpha (REG3a)
Gene Names
REG3A; HIP; PAP; PAP1; REG3; INGAP; PAP-H; PBCGF; HIP/PAP; REG-III
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150146_BIOACTIVITY11.jpg Bioactivity (Growth arrest and DNA-damage-inducible protein GADD45 alpha (GADD45a) is a member of the GADD45 family. It may affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. Besides, Proliferating Cell Nuclear Antigen (PCNA) has been identified as an interactor of GADD45a, thus a binding ELISA assay was conducted to detect the interaction of recombinant rat GADD45a and recombinant rat PCNA. Briefly, GADD45a were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to PCNA-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-GADD45a pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of GADD45a and PCNA was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of GADD45a with PCNA.)

Growth Arrest And DNA Damage Inducible Protein Alpha, Active Protein (Cat# AAA150146)

Full Name
Active Growth Arrest And DNA Damage Inducible Protein Alpha (GADD45a)
Gene Names
Gadd45a; Ddit1; Gadd45
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150561_WB11.jpg WB (Western Blot) (WB Image)

Angiotensin I Converting Enzyme 2 (ACE2), Active Protein (Cat# AAA150561)

Full Name
Active Angiotensin I Converting Enzyme 2 (ACE2)
Gene Names
ACE2; ACEH
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA152129_SDS_PAGE13.jpg SDS-PAGE (SDS-PAGE)

Acid Sphingomyelinase (ASM), Active Protein (Cat# AAA152129)

Full Name
Active Acid Sphingomyelinase (ASM)
Gene Names
SMPD1; ASM; NPD; ASMASE
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA152060_WB8.jpg WB (Western Blot) (Sample: Active recombinant AST, Human)

Aspartate Aminotransferase (AST), Active Protein (Cat# AAA152060)

Full Name
Active Aspartate Aminotransferase (AST)
Gene Names
GOT1; cCAT; GIG18; cAspAT; ASTQTL1
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing

Interferon alpha-2b, Active Protein (Cat# AAA62203)

Full Name
Human Interferon alpha-2b (INF alpha-2b), yeast
Purity
> 97% (by SDS-PAGE and HPLC)
Pricing

Creatine Kinase MB (CK-MB) Type II, Recombinant, Active Protein (Cat# AAA58330)

Full Name
CK-MB Type II, Recombinant
Purity
SDS-PAGE followed by Coomassie staining must demostrate a doublet band migrating at ~47 kDa.
Testing Result: Pass
Pricing
product-image-AAA48391_BIOACTIVITY13.jpg Bioactivity (CD200 Subunit is coated at 10 ug/ml (100 ul/well) can bind Human CD200R1 (CAT# ATGP3809) in a Functional ELISA assay.)

CD200, Active Protein (Cat# AAA48391)

Full Name
Recombinant human CD200 protein
Gene Names
CD200; MRC; MOX1; MOX2; OX-2
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
product-image-AAA48394_BIOACTIVITY13.jpg Bioactivity (Human TL1A/TNFSF15 (CAT# ATGP1049) is coated at 10 ug/ml (100 ul/well) can bind Human DR3/TNFRSF25. The ED50 range )

DR3/TNFRSF25, Active Protein (Cat# AAA48394)

Full Name
Recombinant human DR3/TNFRSF25 protein
Gene Names
TNFRSF25; DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
product-image-AAA48404_BIOACTIVITY13.jpg Bioactivity (Human EPHB1 is coated at 2 ug/ml (100 ul/well) can bind Human EFNB1 (CAT# ATGP3800) in a Functional ELISA assay.)

EphB1, Active Protein (Cat# AAA48404)

Full Name
Recombinant human EphB1 protein
Gene Names
EPHB1; ELK; NET; Hek6; EPHT2
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
product-image-AAA48410_BIOACTIVITY13.jpg Bioactivity (Mouse SPP1 stimulates cell adhesion of the HEK293 human embryonic kidney cells. The ED50 range )

Osteopontin/OPN, Active Protein (Cat# AAA48410)

Full Name
Recombinant mouse Osteopontin/OPN protein
Applications
Bioactivity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
product-image-AAA48459_BIOACTIVITY13.jpg Bioactivity (Human IL-2 (C145S) stimulates cell proliferation of the CTLL2 mouse cytotoxic T cells. The ED50 range ≥0.65 ng/ml)

Interleukin-2, Active Protein (Cat# AAA48459)

Full Name
Interleukin-2 (C145S), 22-153 aa, Human, E Coli (Bioactivity Validated)
Gene Names
IL2; IL-2; TCGF; lymphokine
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
product-image-AAA48322_BIOACTIVITY13.jpg Bioactivity (Human IL-9 stimulates cell proliferation of the MO7e human megakaryocytic leukemic cells. The ED50 range )

IL-9, Active Protein (Cat# AAA48322)

Full Name
Recombinant IL-9
Gene Names
IL9; P40; HP40; IL-9
Applications
Bioactivity, SDS-PAGE
Purity
> 85% by SDS - PAGE
Pricing
product-image-AAA48476_SDS_PAGE15.jpg SDS-PAGE

Interleukin-3, Active Protein (Cat# AAA48476)

Full Name
Interleukin-3, 20-152aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
IL3; IL-3; MCGF; MULTI-CSF
Applications
SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing
product-image-AAA48526_SDS_PAGE15.jpg SDS-PAGE

SOD1, Active Protein (Cat# AAA48526)

Full Name
SOD1, 1-154aa, Human, E Coli (Bioactivity Validated)
Gene Names
SOD1; ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing

TGF-beta RII, Active Protein (Cat# AAA48997)

Full Name
Recombinant human TGF-beta RII protein
Gene Names
TGFBR2; AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing

Transforming Growth Factor-Beta 3, Active Protein (Cat# AAA76535)

Full Name
Transforming Growth Factor-Beta 3, Recombinant Protein
Gene Names
TGFB3; ARVD; LDS5; RNHF; ARVD1; TGF-beta3
Purity
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing

Caspase-5, Active Protein (Cat# AAA77045)

Full Name
Caspase-5 (human), (recombinant)
Gene Names
CASP5; ICH-3; ICEREL-III; ICE(rel)III
Purity
>80% (SDS-PAGE)
Pricing

HDAC2, Active Protein (Cat# AAA77050)

Full Name
HDAC2 (full-length) (human), (recombinant)
Purity
Partially purified by single-step affinity chromatography and gel filtration
Pricing

IGF-1, Active Protein (Cat# AAA79164)

Full Name
Human IGF-1
Gene Names
IGF1; IGFI; IGF-I; IGF1A
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing

VE-Statin/EGFL-7, Active Protein (Cat# AAA79165)

Full Name
Human VE-Statin/EGFL7
Gene Names
EGFL7; NEU1; ZNEU1; VE-STATIN; RP11-251M1.2
Reactivity
Human
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing

RELM alpha, Active Protein (Cat# AAA79173)

Full Name
Mouse RELM alpha
Gene Names
Retnla; HIMF; Xcp2; Fizz1; RELMa; Fizz-1; RELMalpha; RELM-alpha; 1810019L16Rik
Reactivity
Mouse
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing
product-image-AAA79174_AD13.jpg Application Data

VEGFR-1/Flt-1 (D5), soluble, Active Protein (Cat# AAA79174)

Full Name
Human VEGFR-1/Flt-1 (D5), soluble
Gene Names
FLT1; FLT; FLT-1; VEGFR1; VEGFR-1
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
product-image-AAA79179_AD11.jpg Application Data

VEGF189, Active Protein (Cat# AAA79179)

Full Name
Human VEGF189
Gene Names
VEGFA; VPF; VEGF; MVCD1
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
product-image-AAA79181_SDS_PAGE15.jpg SDS-PAGE (SDS-PAGE analysis of recombinant human soluble TIE-2/Fc produced from insect cells. Sample was loaded in 10% SDS-polyacrylamide gel under reducing condition and stained with Coomassie blue.)

TIE-2/Fc Chimera, soluble, Active Protein (Cat# AAA79181)

Full Name
Human TIE-2/Fc Chimera, soluble
Gene Names
TEK; TIE2; VMCM; TIE-2; VMCM1; CD202B
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
product-image-AAA79187_AD13.jpg Application Data

BMP-2, Active Protein (Cat# AAA79187)

Full Name
Human BMP-2
Gene Names
BMP2; BDA2; BMP2A
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing

GDF-11, Active Protein (Cat# AAA79190)

Full Name
Human GDF-11
Gene Names
GDF11; BMP11; BMP-11
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analysis
Pricing
product-image-AAA79193_AD13.jpg Application Data

IL-3, Active Protein (Cat# AAA79193)

Full Name
Human IL-3
Gene Names
IL3; IL-3; MCGF; MULTI-CSF
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
product-image-AAA79214_AD13.jpg Application Data

GM-CSF, Active Protein (Cat# AAA79214)

Full Name
Human GM-CSF
Gene Names
CSF2; GMCSF
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
product-image-AAA79220_AD13.jpg Application Data

VEGF165, Active Protein (Cat# AAA79220)

Full Name
Human VEGF165
Gene Names
VEGFA; VPF; VEGF; MVCD1
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
product-image-AAA79221_SDS_PAGE11.jpg SDS-PAGE

EGF, Active Protein (Cat# AAA79221)

Full Name
Human EGF
Gene Names
EGF; URG; HOMG4
Purity
> 95% by SDS-PAGE & silver stain
Pricing
product-image-AAA79306_AD15.jpg Application Data

CD105/Endoglin, soluble, Active Protein (Cat# AAA79306)

Full Name
Human CD105/Endoglin, soluble
Gene Names
ENG; END; HHT1; ORW1
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
product-image-AAA79308_AD13.jpg Application Data

VEGF120, Active Protein (Cat# AAA79308)

Full Name
Mouse VEGF120
Gene Names
Vegfa; Vpf; Vegf
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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