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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 950-1000 of 2567 product results


product-image-AAA79261_AD13.jpg Application Data

VEGF120, Active Protein (Cat# AAA79261)

No reviews yet
Full Name
Mouse VEGF120
Gene Names
Vegfa; Vpf; Vegf
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing

VEGFR-2/KDR-Fc Chimera, soluble, Active Protein (Cat# AAA79265)

No reviews yet
Full Name
Human VEGFR-2/KDR-Fc Chimera, soluble
Gene Names
KDR; FLK1; CD309; VEGFR; VEGFR2
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing

GRO-alpha/MGSA (CXCL1), Active Protein (Cat# AAA79276)

No reviews yet
Full Name
Human GRO-alpha/MGSA (CXCL1)
Gene Names
CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analyses
Pricing
product-image-AAA79286_AD15.jpg Application Data

PlGF, Active Protein (Cat# AAA79286)

No reviews yet
Full Name
Mouse PlGF
Gene Names
Pgf; PIGF; Plgf; AI854365
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing

NNT-1/BCSF-3, Active Protein (Cat# AAA79298)

No reviews yet
Full Name
Human NNT-1/BCSF-3
Gene Names
CLCF1; CLC; NR6; BSF3; NNT1; BSF-3; CISS2; NNT-1
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analysis
Pricing
product-image-AAA79301_AD13.jpg Application Data

CNTF, Active Protein (Cat# AAA79301)

No reviews yet
Full Name
Rat CNTF
Reactivity
Rat
Purity
> 98% by SDS-PAGE & silver stain
Pricing
product-image-AAA79317_AD13.jpg Application Data (Binding of Biotinylated VEGF165 to anti-human VEGF-A #3C5 in a functional ELISA. Anti-human VEGF-A antibody was coated with 0,5ug/ml (100ul/well) and Biotinylated VEGF165 was added starting with 3.125 ng/ml to 200 ng/ml.)

VEGF165, Active Protein (Cat# AAA79317)

No reviews yet
Full Name
Human VEGF165-Biotin
Gene Names
VEGFA; VPF; VEGF; MVCD1
Reactivity
Human
Purity
> 95% by SDS-PAGE & Coomassie stain
Pricing
product-image-AAA79318_AD13.jpg Application Data (Binding of Biotinylated VEGF165 to anti-human VEGF-A #3C5 in a functional ELISA. Anti-human VEGF-A antibody was coated with 0,5ug/ml (100ul/well) and Biotinylated VEGF165 was added starting with 3.125 ng/ml to 200 ng/ml.)

VEGF165, Active Protein (Cat# AAA79318)

No reviews yet
Full Name
Human VEGF165-Biotin
Gene Names
VEGFA; VPF; VEGF; MVCD1
Reactivity
Human
Purity
> 95% by SDS-PAGE & Coomassie stain
Pricing
product-image-AAA79319_AD13.jpg Application Data (VEGF-B167 BioLISA using recombinant human soluble Flt-1 for capturing and recombinant human VEGF-B167 as standard. A mouse anti-human VEGF-B antibody in combination with a goat anti-mouse Biotin-conjugated antibody was used for detection.)

VEGF-B167, Active Protein (Cat# AAA79319)

No reviews yet
Full Name
Human VEGF-B167
Gene Names
VEGFB; VRF; VEGFL
Reactivity
Human
Purity
> 98% by SDS-PAGE & Coomassie stain
Pricing

IL-6 receptor alpha, Active Protein (Cat# AAA79325)

No reviews yet
Full Name
Human IL-6 receptor alpha, soluble
Gene Names
IL6R; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1
Reactivity
Human
Purity
> 95% by SDS-PAGE & HPLC analyses
Pricing

VEGF120, Active Protein (Cat# AAA79185)

No reviews yet
Full Name
Mouse VEGF120
Gene Names
Vegfa; Vpf; Vegf
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
product-image-AAA79206_AD13.jpg Application Data

FGF-4, Active Protein (Cat# AAA79206)

No reviews yet
Full Name
Mouse FGF-4
Gene Names
Fgf4; KS3; hst; Fgfk; Hst1; kFGF; Fgf-4; hst-1; Hstf-1
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
product-image-AAA79208_AD13.jpg Application Data

IL-4, Active Protein (Cat# AAA79208)

No reviews yet
Full Name
Human IL-4
Gene Names
IL4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
product-image-AAA79226_AD11.jpg Application Data

VEGFR-2/KDR (native), soluble, Active Protein (Cat# AAA79226)

No reviews yet
Full Name
Human VEGFR-2/KDR (native), soluble
Gene Names
KDR; FLK1; CD309; VEGFR; VEGFR2
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing

Thioredoxin Reductase, Active Protein (Cat# AAA78970)

No reviews yet
Full Name
Thioredoxin Reductase (yeast) (rNTR (yeast))
Pricing
product-image-AAA79147_AD13.jpg Application Data

PlGF, Active Protein (Cat# AAA79147)

No reviews yet
Full Name
Rat PlGF
Gene Names
Pgf; Plgf
Reactivity
Rat
Purity
> 95% by SDS-PAGE & silver stain
Pricing

GM-CSF, Active Protein (Cat# AAA79155)

No reviews yet
Full Name
Mouse GM-CSF
Gene Names
Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing

Carboxypeptidase-B, Active Protein (Cat# AAA79118)

No reviews yet
Full Name
Rat Carboxypeptidase-B
Gene Names
Cpb1; Cpb
Purity
>95% by SDS-PAGE & HPLC analysis
Pricing

SDF-1 alpha (CXCL12), Active Protein (Cat# AAA79145)

No reviews yet
Full Name
Human SDF-1 alpha (CXCL12)
Gene Names
CXCL12; IRH; PBSF; SDF1; TLSF; TPAR1; SCYB12
Reactivity
Human
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing
product-image-AAA176990_SDS_PAGE15.jpg SDS-PAGE

COVID 19 Spike S Protein (RBD) Coronavirus, Active Protein (Cat# AAA176990)

No reviews yet
Full Name
Recombinant 2019-nCoV Spike S Protein (RBD, mFc Tag)
Purity
> 95 % as determined by reducing SDS-PAGE.
Pricing

Complement C4, Active Protein (Cat# AAA224701)

No reviews yet
Full Name
Purified native Human Complement C4 protein
Gene Names
C4a; C4; C4b; C4-1
Purity
> 95% by SDS-PAGE
Pricing
product-image-AAA177933_BIOACTIVITY13.jpg Bioactivity

CD28/TP44, Active Protein (Cat# AAA177933)

No reviews yet
Full Name
Recombinant Human/Cynomolgus CD28/TP44 (N-His)
Gene Names
CD28; Tp44
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA177939_BIOACTIVITY13.jpg Bioactivity

Interleukin-36 alpha/IL-36 alpha, Active Protein (Cat# AAA177939)

No reviews yet
Full Name
Recombinant Human Interleukin-36 alpha/IL-36 alpha
Gene Names
IL36A; FIL1; FIL1E; IL1F6; IL-1F6; IL1(EPSILON); FIL1(EPSILON)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA177975_BIOACTIVITY13.jpg Bioactivity

Signal-Regulatory Protein alpha-1/SIRPA/CD172a, Active Protein (Cat# AAA177975)

No reviews yet
Full Name
Recombinant Cynomolgus Signal-Regulatory Protein alpha-1/SIRPA/CD172a (C-6His)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA177976_BIOACTIVITY13.jpg Bioactivity

Interleukin-17A/IL-17A, Active Protein (Cat# AAA177976)

No reviews yet
Full Name
Recombinant Cynomolgus Interleukin-17A/IL-17A (C-6His)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA176991_WB15.jpg WB (Western Blot)

COVID 19 Spike S Protein (RBD) Coronavirus, Active Protein (Cat# AAA176991)

No reviews yet
Full Name
Recombinant 2019-nCoV Spike S Protein (RBD, mFc Tag)
Purity
> 95 % as determined by reducing SDS-PAGE.
Pricing
product-image-AAA173583_SDS_PAGE15.jpg SDS-PAGE

ADAM15 / MDC15, Active Protein (Cat# AAA173583)

No reviews yet
Full Name
Recombinant Mouse ADAM15 / MDC15 Protein (His tag)
Gene Names
Adam15; AD56; MDC15
Purity
> 90 % as determined by SDS-PAGE
Pricing

PHOSPHORYLASE B, Active Protein (Cat# AAA50505)

No reviews yet
Full Name
NATIVE RABBIT PHOSPHORYLASE B
Applications
ELISA
Purity
Protein: 95%
Pricing

Wnt1, Active Protein (Cat# AAA75438)

No reviews yet
Full Name
Wnt1 protein
Purity
> 98% by SDS-PAGE gel and HPLC analysis
Pricing

WISP1, Active Protein (Cat# AAA75458)

No reviews yet
Full Name
WISP1 protein
Gene Names
WISP1; CCN4; WISP1c; WISP1i; WISP1tc
Purity
> 98% pure
Pricing

Factor X, Active Protein (Cat# AAA71837)

No reviews yet
Full Name
Human Factor X
Gene Names
F10; fX; Cf10
Purity
>95% by SDS-PAGE analysis; Purified using a combination of conventional techniques and immunoaffinity chromatography.
Pricing

GST Yb2, Active Protein (Cat# AAA71846)

No reviews yet
Full Name
GST Yb2, Rat Liver
Applications
Western Blot
Purity
Homogeneous by SDS gel electrophoresis.
Pricing

sDLL4, Active Protein (Cat# AAA75582)

No reviews yet
Full Name
sDLL4 protein
Gene Names
DLL4; hdelta2
Purity
> 95% pure
Pricing

Pepsinogen I, Active Protein (Cat# AAA75592)

No reviews yet
Full Name
Pepsinogen I protein
Purity
> 90% by SDS-PAGE
Pricing

IL21, Active Protein (Cat# AAA75599)

No reviews yet
Full Name
IL21 protein
Gene Names
IL21; Za11; IL-21; CVID11
Purity
> 95.0% by SDS-PAGE
Pricing

IL-13 alpha 2 receptor (IL13RA2), Active Protein (Cat# AAA76103)

No reviews yet
Full Name
Human IL-13 alpha 2 receptor Recombinant (IL13RA2)
Purity
>98%, as determined by SDS-PAGE and HPLC
Pricing

CD200 (MOX1), Active Protein (Cat# AAA76111)

No reviews yet
Full Name
Mouse CD200 Recombinant (MOX1)
Purity
>98%, as determined by SDS-PAGE and HPLC
Pricing
product-image-AAA76120_BIOACTIVITY13.jpg Bioactivity (The activity was determined by immobilized Spike Protein S1 binding with human ACE2 in a functional ELISA assay, the ED50 was determined to be 3.8nM.2019-ncov S1-his tagged (coating at 0.5ug-well) binding with Human ACE2-Fc (cat. The linear range was found to be 0.1-5 ug/ml)

COVID 19 Spike S1 Coronavirus, Active Protein (Cat# AAA76120)

No reviews yet
Full Name
2019 nCoV/COVID19 Spike protein S1 Recombinant-His
Purity
> 90% by SDS-PAGE.
Pricing

PAI2, Active Protein (Cat# AAA75570)

No reviews yet
Full Name
PAI2 protein
Gene Names
SERPINB2; PAI; PAI2; PAI-2; PLANH2; HsT1201
Purity
> 95% pure
Pricing

PDGF CC, Active Protein (Cat# AAA75572)

No reviews yet
Full Name
PDGF CC protein
Gene Names
PDGFC; SCDGF; FALLOTEIN
Purity
> 98% pure
Pricing

sFRP1, Active Protein (Cat# AAA75573)

No reviews yet
Full Name
sFRP1 protein
Gene Names
SFRP1; FRP; FRP1; FrzA; FRP-1; SARP2
Purity
> or = 97% by SDS-PAGE and HPLC
Pricing

Klotho, Active Protein (Cat# AAA75575)

No reviews yet
Full Name
Klotho protein
Purity
> 98% pure
Pricing

Transforming Growth Factor-Beta 3, Active Protein (Cat# AAA76535)

No reviews yet
Full Name
Transforming Growth Factor-Beta 3, Recombinant Protein
Gene Names
TGFB3; ARVD; LDS5; RNHF; ARVD1; TGF-beta3
Purity
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing
product-image-AAA76382_ELISA13.jpg ELISA (SARS COV2 S B.1.1.529 trimer ACE functional binding ELISA assay2019-ncov S B.1.1.529 trimer(coating at 0.1ug-well) binding with Human ACE2-Fc.The linear range was found to be 23 ng/ml)

SARS COV2 Spike protein S B.1.1.529 (omicron) Trimer, Active Protein (Cat# AAA76382)

No reviews yet
Full Name
SARS COV2 Spike protein S B.1.1.529 (omicron) Trimer Recombinant
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
product-image-AAA76383_AD13.jpg Application Data (Polarized membrane extensions mediate osteoclast fusion.(D, top) Immunoblot analysis of lysates of RAW264.7 macrophages stimulated with RANKL for the indicated times with antibodies to Ser473-phosphorylated (p) or total forms of Akt.)

Soluble RANK ligand, Active Protein (Cat# AAA76383)

No reviews yet
Full Name
Human Soluble RANK ligand Recombinant
Gene Names
TNFSF11; ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TRANCE; hRANKL2
Purity
>98%, as determined by SDS-PAGE and HPLC
Pricing
product-image-AAA76387_AD13.jpg Application Data ((A) Nitrite production by HT-29 cells following 48 h of treatment with cytokines.Effect of 0–50 ng/ml TNF-? on nitrite production induced by 100 U/ml IFN-? and 10 ng/ml IL-1? in HT-29 cells following 48 h of treatment.)

Interferon-beta 1b, Active Protein (Cat# AAA76387)

No reviews yet
Full Name
Human Interferon-beta 1b Recombinant
Gene Names
IFNB1; IFB; IFF; IFNB
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
product-image-AAA76397_AD11.jpg Application Data (Effects of ACM from Olig2PC-Astros and NPC-Astros on neurons.(h and i) RT-PCR analysis of the expression of the antioxidant defense-related genes, GCLC and NFE2L2 (n=3), and the neurotrophic growth factor genes, BDNF, GDNF and NT-3 (n=3).)

Glial-Derived Neurotrophic Factor, Active Protein (Cat# AAA76397)

No reviews yet
Full Name
Mouse Glial-Derived Neurotrophic Factor Recombinant
Gene Names
Gdnf; AI385739
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
product-image-AAA79174_AD13.jpg Application Data

VEGFR-1/Flt-1 (D5), soluble, Active Protein (Cat# AAA79174)

No reviews yet
Full Name
Human VEGFR-1/Flt-1 (D5), soluble
Gene Names
FLT1; FLT; FLT-1; VEGFR1; VEGFR-1
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
product-image-AAA79179_AD11.jpg Application Data

VEGF189, Active Protein (Cat# AAA79179)

No reviews yet
Full Name
Human VEGF189
Gene Names
VEGFA; VPF; VEGF; MVCD1
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
product-image-AAA79181_SDS_PAGE15.jpg SDS-PAGE (SDS-PAGE analysis of recombinant human soluble TIE-2/Fc produced from insect cells. Sample was loaded in 10% SDS-polyacrylamide gel under reducing condition and stained with Coomassie blue.)

TIE-2/Fc Chimera, soluble, Active Protein (Cat# AAA79181)

No reviews yet
Full Name
Human TIE-2/Fc Chimera, soluble
Gene Names
TEK; TIE2; VMCM; TIE-2; VMCM1; CD202B
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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